Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relB-parE/ParE-RHH |
| Location | 4232782..4233338 | Replicon | chromosome |
| Accession | NZ_CP086180 | ||
| Organism | Xanthomonas oryzae strain PXO363 | ||
Toxin (Protein)
| Gene name | parE | Uniprot ID | - |
| Locus tag | LL927_RS19945 | Protein ID | WP_229001948.1 |
| Coordinates | 4233087..4233338 (+) | Length | 84 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | A0A854CIX2 |
| Locus tag | LL927_RS19940 | Protein ID | WP_011408759.1 |
| Coordinates | 4232782..4233060 (+) | Length | 93 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LL927_RS19920 (LL927_19895) | 4227899..4228456 | - | 558 | WP_011259349.1 | DNA-3-methyladenine glycosylase | - |
| LL927_RS19925 (LL927_19900) | 4228606..4229571 | - | 966 | WP_109181928.1 | IS1595-like element ISXo5 family transposase | - |
| LL927_RS19930 (LL927_19905) | 4230152..4231336 | + | 1185 | WP_011408397.1 | IS256-like element IS1113 family transposase | - |
| LL927_RS19935 (LL927_19910) | 4232242..4232586 | + | 345 | WP_199285675.1 | hypothetical protein | - |
| LL927_RS19940 (LL927_19915) | 4232782..4233060 | + | 279 | WP_011408759.1 | CopG family ribbon-helix-helix protein | Antitoxin |
| LL927_RS19945 (LL927_19920) | 4233087..4233338 | + | 252 | WP_229001948.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| LL927_RS19950 (LL927_19925) | 4233599..4233796 | + | 198 | WP_004541336.1 | hypothetical protein | - |
| LL927_RS19955 (LL927_19930) | 4233865..4234119 | + | 255 | WP_223293127.1 | hypothetical protein | - |
| LL927_RS19960 (LL927_19935) | 4234336..4234455 | + | 120 | Protein_3819 | IS3 family transposase | - |
| LL927_RS19965 | 4234424..4234552 | + | 129 | WP_012444694.1 | hypothetical protein | - |
| LL927_RS19975 (LL927_19945) | 4234983..4235384 | - | 402 | WP_011259345.1 | H-NS family nucleoid-associated regulatory protein | - |
| LL927_RS19980 (LL927_19950) | 4235606..4235782 | + | 177 | Protein_3822 | DUF3606 domain-containing protein | - |
| LL927_RS19985 (LL927_19955) | 4236064..4236401 | + | 338 | Protein_3823 | ATP-dependent DNA ligase | - |
| LL927_RS19990 (LL927_19960) | 4236477..4237568 | - | 1092 | WP_041182166.1 | ribonuclease D | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 84 a.a. Molecular weight: 9603.92 Da Isoelectric Point: 9.9718
>T222657 WP_229001948.1 NZ_CP086180:4233087-4233338 [Xanthomonas oryzae]
MLRLREFLRPKNPDAARRAGEAIRRGVQALGAHPRMGRLIEDLSEQYREWLIDFGDSGYVARYRFDGDTVTILAVRHQKE
AGY
MLRLREFLRPKNPDAARRAGEAIRRGVQALGAHPRMGRLIEDLSEQYREWLIDFGDSGYVARYRFDGDTVTILAVRHQKE
AGY
Download Length: 252 bp
>T222657 NZ_CP117993:2172677-2173162 [Enterobacter hormaechei]
GTGGGACGTGTAACAGCACCAGAGCCCTTATCCAGCGTCCATCAACTGGCGGAGTTCGTCAGCGGAGAGGCCGTGCTTGA
CGAATGGCTAAAACAAAGAGGTCTGAAAAACCAGGCGCTCGGCGCAGCCCGAACGTTTGTCGTTTGTAAAACGGGCACGA
AGCAGGTCGCGGGATTTTACTCTCTGGCTACCGGCAGCGTTAACCATACGCAAGCGACAGGTAATCTGCGGCGTAACATG
CCGGATCCCATTCCCGTGATTATACTTGCCCGTCTGGCTGTGGATGTCTCGTTACGCGGAAACGGGTTGGGAGCCGATTT
ACTCCACGATGCGGTTTTACGCTGTTATCGGGTAGCTGAGAATATCGGGGTGCGAGCGATCATGGTTCATGCACTCACTG
AGGAAGCCAAAGCGTTTTATATCCACCATGGTTTTAAAGCATCGCAGACTCAGGAACGGACACTGTTTCTCAGGCTTCCT
CAGTAG
GTGGGACGTGTAACAGCACCAGAGCCCTTATCCAGCGTCCATCAACTGGCGGAGTTCGTCAGCGGAGAGGCCGTGCTTGA
CGAATGGCTAAAACAAAGAGGTCTGAAAAACCAGGCGCTCGGCGCAGCCCGAACGTTTGTCGTTTGTAAAACGGGCACGA
AGCAGGTCGCGGGATTTTACTCTCTGGCTACCGGCAGCGTTAACCATACGCAAGCGACAGGTAATCTGCGGCGTAACATG
CCGGATCCCATTCCCGTGATTATACTTGCCCGTCTGGCTGTGGATGTCTCGTTACGCGGAAACGGGTTGGGAGCCGATTT
ACTCCACGATGCGGTTTTACGCTGTTATCGGGTAGCTGAGAATATCGGGGTGCGAGCGATCATGGTTCATGCACTCACTG
AGGAAGCCAAAGCGTTTTATATCCACCATGGTTTTAAAGCATCGCAGACTCAGGAACGGACACTGTTTCTCAGGCTTCCT
CAGTAG
Antitoxin
Download Length: 93 a.a. Molecular weight: 10826.11 Da Isoelectric Point: 4.9736
>AT222657 WP_011408759.1 NZ_CP086180:4232782-4233060 [Xanthomonas oryzae]
MVTATSIKLDDELKGRVQHLAESRRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK
MVTATSIKLDDELKGRVQHLAESRRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK
Download Length: 279 bp
>AT222657 NZ_CP117993:2172423-2172689 [Enterobacter hormaechei]
ATGAAATCAGATGTTCAACTCAATCTCAGAGCCAAAGAATCCCAGCGGGCGCTTATCGATGCCGCCGCAGAGATCCTCCA
TAAATCACGCACGGACTTCATTCTGGAGATGGCCTGTCAGGCAGCCGAGAATGTGATCCTCGATCGACGTGTATTCAATT
TTAACGATGAACAGTACGCAGAGTTCATTGACATGCTCGATGCCCCGGTCGCGGACGATCCTGCCATAGAAAAACTGCTG
GCAAGGAAACCGCAGTGGGACGTGTAA
ATGAAATCAGATGTTCAACTCAATCTCAGAGCCAAAGAATCCCAGCGGGCGCTTATCGATGCCGCCGCAGAGATCCTCCA
TAAATCACGCACGGACTTCATTCTGGAGATGGCCTGTCAGGCAGCCGAGAATGTGATCCTCGATCGACGTGTATTCAATT
TTAACGATGAACAGTACGCAGAGTTCATTGACATGCTCGATGCCCCGGTCGCGGACGATCCTGCCATAGAAAAACTGCTG
GCAAGGAAACCGCAGTGGGACGTGTAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|