Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | EcnAB/- |
| Location | 1764051..1764401 | Replicon | chromosome |
| Accession | NZ_CP086180 | ||
| Organism | Xanthomonas oryzae strain PXO363 | ||
Toxin (Protein)
| Gene name | EcnB | Uniprot ID | G7TLC7 |
| Locus tag | LL927_RS08450 | Protein ID | WP_011257368.1 |
| Coordinates | 1764051..1764185 (-) | Length | 45 a.a. |
Antitoxin (Protein)
| Gene name | EcnA | Uniprot ID | G7TLC8 |
| Locus tag | LL927_RS08455 | Protein ID | WP_011407410.1 |
| Coordinates | 1764249..1764401 (-) | Length | 51 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LL927_RS08435 (LL927_08415) | 1761068..1762012 | - | 945 | WP_027704118.1 | MBL fold metallo-hydrolase | - |
| LL927_RS08440 (LL927_08420) | 1762143..1763432 | - | 1290 | WP_069959696.1 | tryptophan--tRNA ligase | - |
| LL927_RS08445 (LL927_08425) | 1763601..1763810 | - | 210 | WP_011407411.1 | CsbD family protein | - |
| LL927_RS08450 (LL927_08430) | 1764051..1764185 | - | 135 | WP_011257368.1 | entericidin A/B family lipoprotein | Toxin |
| LL927_RS08455 (LL927_08435) | 1764249..1764401 | - | 153 | WP_011407410.1 | entericidin A/B family lipoprotein | Antitoxin |
| LL927_RS08460 (LL927_08440) | 1764509..1765432 | - | 924 | WP_011407409.1 | arginase | - |
| LL927_RS08465 (LL927_08445) | 1765754..1765972 | + | 219 | Protein_1615 | hypothetical protein | - |
| LL927_RS08470 (LL927_08450) | 1765964..1766419 | + | 456 | Protein_1616 | hypothetical protein | - |
| LL927_RS08475 (LL927_08455) | 1766416..1766958 | + | 543 | Protein_1617 | GTPase | - |
| LL927_RS08480 (LL927_08460) | 1767438..1768121 | + | 684 | WP_011257363.1 | dTMP kinase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 45 a.a. Molecular weight: 4457.33 Da Isoelectric Point: 10.2040
>T222654 WP_011257368.1 NZ_CP086180:c1764185-1764051 [Xanthomonas oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK
Download Length: 135 bp
>T222654 NZ_CP117989:484281-485222 [Vibrio campbellii]
ATGAACACACTAAAACAACAGTTCCTTGAGGTTTCCGATGCGCTTGAGCTCGGAAACCCAGCCATTATTGAAAAAGATTA
CTGGGTCGTGGCTTTACTGGCTGAGCTAGCGAAAGTTTGTCCTGAGCATCATCAAATGGTCTTTTCTGGCGGCACGGCGT
TGGCGAAATCAAACGTTAAAATTCTAAGAATGTCGGAAGATGTGGATATAAAACTCATCCCCAACCCAGCATTTGATGAA
CTGAGTCGAGCGAAAAAGAAAGCCACGAGAAAGGCATGTGTTAACAAGATTGAACAGGCGCTCACCCAGTCAGGGCGATT
TAACGTTGAAACGCGTTCTGTGCGAGATGAGTACCGCTACGTCGAGTTTGAACTTAAATACCCGCAGCAGTTTAGTCAAG
CGCCCTGCCTGCGCCCCATCATCAAGTTAGAGTTAATCGAAACCATTCCATTACTGGATGTGGAGTCGCGCAGCATTCAA
TCTCTGGTAGCAGAGTTGTACCAACAACCACAAGAAGTGAGTGCATTTGATTGCGTCTCTATCCATGCCACATTGGTTGA
AAAAATTATTTCAATGCTGCGCCGTACCATGTCGGTAAAACGCAATACGGAGCGAAGCGATGATGTTGCTTTAGTTCGCC
ATATTTACGATGTGCACTGCATAACAAAACTCTCAATGCCAGAACTCGACTCGATTGACGGTCTATTCAAAGCGGTATTG
GCAGAAGATATTGCCCGCTTTGGCAATCAACATGCAGAGTTTGTTGCCAACCCCAAACAAGAGCTACAACTTGGCCTTAA
AGAGCTTGAGGAAAATGCAATATTCCGCCAACGCTTTCAGGAATTTGTCACGCCAATGGTGTTTAACACCGAACCCCATG
ATTTTGATACCTGCTTTGCCTCATTTAAACGCATTGCAGCATCGCTAATTGAAAAAATTTAA
ATGAACACACTAAAACAACAGTTCCTTGAGGTTTCCGATGCGCTTGAGCTCGGAAACCCAGCCATTATTGAAAAAGATTA
CTGGGTCGTGGCTTTACTGGCTGAGCTAGCGAAAGTTTGTCCTGAGCATCATCAAATGGTCTTTTCTGGCGGCACGGCGT
TGGCGAAATCAAACGTTAAAATTCTAAGAATGTCGGAAGATGTGGATATAAAACTCATCCCCAACCCAGCATTTGATGAA
CTGAGTCGAGCGAAAAAGAAAGCCACGAGAAAGGCATGTGTTAACAAGATTGAACAGGCGCTCACCCAGTCAGGGCGATT
TAACGTTGAAACGCGTTCTGTGCGAGATGAGTACCGCTACGTCGAGTTTGAACTTAAATACCCGCAGCAGTTTAGTCAAG
CGCCCTGCCTGCGCCCCATCATCAAGTTAGAGTTAATCGAAACCATTCCATTACTGGATGTGGAGTCGCGCAGCATTCAA
TCTCTGGTAGCAGAGTTGTACCAACAACCACAAGAAGTGAGTGCATTTGATTGCGTCTCTATCCATGCCACATTGGTTGA
AAAAATTATTTCAATGCTGCGCCGTACCATGTCGGTAAAACGCAATACGGAGCGAAGCGATGATGTTGCTTTAGTTCGCC
ATATTTACGATGTGCACTGCATAACAAAACTCTCAATGCCAGAACTCGACTCGATTGACGGTCTATTCAAAGCGGTATTG
GCAGAAGATATTGCCCGCTTTGGCAATCAACATGCAGAGTTTGTTGCCAACCCCAAACAAGAGCTACAACTTGGCCTTAA
AGAGCTTGAGGAAAATGCAATATTCCGCCAACGCTTTCAGGAATTTGTCACGCCAATGGTGTTTAACACCGAACCCCATG
ATTTTGATACCTGCTTTGCCTCATTTAAACGCATTGCAGCATCGCTAATTGAAAAAATTTAA
Antitoxin
Download Length: 51 a.a. Molecular weight: 5046.99 Da Isoelectric Point: 8.7942
>AT222654 WP_011407410.1 NZ_CP086180:c1764401-1764249 [Xanthomonas oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC
Download Length: 153 bp
>AT222654 NZ_CP117989:483875-484279 [Vibrio campbellii]
ATGACAGCAGTAGACCGCATTTGTCAAAAGATAAAGCGTTCAAGACGTTATGTATTTGAACGCAAAGACTTTGATGGATT
TGCAAGTTACGACCAAATAGGTCGGGCCCTGAGGCAGCTTGTGCAGCAAGGTGAGTTAATGAAGCTTGGCTATGGCTTGT
ATACCAAAGCAAGAATCAATAGCCTCACAGGTAAGCCTATGCCGACTAATCCGGGAGGGACCGATGCCCTTATGCGAGAA
ATTCTTAAAATGAAAGGCGTTGATTTTGAGATGGATAGTCTATCGCTACAAAGTCTTTCAGGTTCAAGCACCCAAATTCC
ATCTTCTATTCAGTATTCATGGGACCCAAAACAGTTTAATCGCAAACTGGTGGTCGGTAGCCGTGTGCTGAACTTACCAA
GTTAG
ATGACAGCAGTAGACCGCATTTGTCAAAAGATAAAGCGTTCAAGACGTTATGTATTTGAACGCAAAGACTTTGATGGATT
TGCAAGTTACGACCAAATAGGTCGGGCCCTGAGGCAGCTTGTGCAGCAAGGTGAGTTAATGAAGCTTGGCTATGGCTTGT
ATACCAAAGCAAGAATCAATAGCCTCACAGGTAAGCCTATGCCGACTAATCCGGGAGGGACCGATGCCCTTATGCGAGAA
ATTCTTAAAATGAAAGGCGTTGATTTTGAGATGGATAGTCTATCGCTACAAAGTCTTTCAGGTTCAAGCACCCAAATTCC
ATCTTCTATTCAGTATTCATGGGACCCAAAACAGTTTAATCGCAAACTGGTGGTCGGTAGCCGTGTGCTGAACTTACCAA
GTTAG
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A0C5UG40 |
Antitoxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A0C5V759 |