222653

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 1100831..1101576 Replicon chromosome
Accession NZ_CP086180
Organism Xanthomonas oryzae strain PXO363

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag LL927_RS05205 Protein ID WP_199285672.1
Coordinates 1100831..1101160 (+) Length 110 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag LL927_RS05210 Protein ID WP_011407754.1
Coordinates 1101157..1101576 (+) Length 140 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LL927_RS05175 (LL927_05160) 1095962..1096633 + 672 WP_011407759.1 class I SAM-dependent methyltransferase -
LL927_RS05185 (LL927_05170) 1096935..1097726 - 792 WP_011407758.1 polysaccharide deacetylase family protein -
LL927_RS05190 (LL927_05175) 1097772..1098698 + 927 WP_011257932.1 Grx4 family monothiol glutaredoxin -
LL927_RS05195 (LL927_05180) 1099030..1099365 + 336 WP_011407757.1 DarT ssDNA thymidine ADP-ribosyltransferase family protein -
LL927_RS05200 (LL927_05185) 1099409..1100728 - 1320 WP_155296575.1 IS701-like element ISXo15 family transposase -
LL927_RS05205 (LL927_05190) 1100831..1101160 + 330 WP_199285672.1 DUF4433 domain-containing protein Toxin
LL927_RS05210 (LL927_05195) 1101157..1101576 + 420 WP_011407754.1 macro domain-containing protein Antitoxin
LL927_RS05215 (LL927_05200) 1101628..1102596 + 969 WP_011258802.1 IS5-like element ISXo1 family transposase -
LL927_RS05220 (LL927_05205) 1102731..1103387 + 657 WP_075246166.1 phosphate phosphatase -
LL927_RS05225 (LL927_05210) 1103425..1104660 - 1236 WP_011257570.1 ISL3-like element ISXoo13 family transposase -
LL927_RS05230 (LL927_05215) 1104962..1105288 + 327 Protein_1006 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside IScluster/Tn - - 1099409..1104660 5251


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(3-108)

Antitoxin

Macro domain

(18-130)


Sequences

Toxin        


Download         Length: 110 a.a.        Molecular weight: 13145.86 Da        Isoelectric Point: 7.1160

>T222653 WP_199285672.1 NZ_CP086180:1100831-1101160 [Xanthomonas oryzae]
MHHVAERRWPFLFTDSHAYCQLASFYSDLSDLDKIDWPLLQARDFRRDPDDPAKFERYQAEALIHRHLPLDGLRGIVCHT
DGLKQTIERQLQERNLKLPVHTRTDWYFR

Download         Length: 330 bp

>T222653 NZ_CP117988:c1561208-1560918 [Vibrio campbellii]
ATGACCTATAAACTCGACTTTAAAAAGAGCGCACTCAAAGAGTGGAAAAAGCTTGGCTCTACTTTGCAACAACAATTTAA
GAAAAAGCTAATCGAGCGCTTAGATAACCCACATGTTCCAGCTTCAAAACTTTCTGGAGCTGACAACATGTATAAAATTA
AGTTGCGTCAATCGGGCTACCGTCTCGTTTACAAAGTTGAAGATGATGTCATCATTGTAACCGTCTTAGCAGTCGGAAAA
CGAGAACGTAGCGATGTTTACCGTAAAGCTATGAAAAGGTTAGATGATTGA

Antitoxin


Download         Length: 140 a.a.        Molecular weight: 15607.02 Da        Isoelectric Point: 6.4733

>AT222653 WP_011407754.1 NZ_CP086180:1101157-1101576 [Xanthomonas oryzae]
MITFTQGNLLESGAEALVNTVNTVGVMGKGIALMFKERFKENFLRYAAACKDNQVRIGKIFVTEVNELDGPRWIINFPTK
QHWRGDSRIEWITEGLQDLHRFLIENKVKSIAIPPLGAGNGGLDWAEVRPLIEEVLGNL

Download         Length: 420 bp

>AT222653 NZ_CP117988:c1561446-1561198 [Vibrio campbellii]
ATGACCACTAGAATTTTGGCTGATGTTGCTGCAAGCATTACTGAGTTGAAAGCTAACCCTATGAAAGTTGCAACTAGTGC
TTACGGCGAACCTGTTGCTGTATTAAACCGAAATGAACCAGCATTTTATTGCGTACCTGCCGAAGCGTACGAAATGATGA
TGGACAGACTCGAAGATCTTGAACTACTCGCTATCGCTAAAGAGCGTGAATCTGAAGAGAGCATTTCGGTAAATATTGAT
GACCTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References