Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 3241517..3242042 Replicon chromosome
Accession NZ_CP086179
Organism Streptomyces fungicidicus strain F1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LLI13_RS14440 Protein ID WP_121546319.1
Coordinates 3241776..3242042 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A7H8J816
Locus tag LLI13_RS14435 Protein ID WP_040908670.1
Coordinates 3241517..3241783 (+) Length 89 a.a.

Genomic Context


LLI13_RS14405LLI13_RS14410LLI13_RS14415LLI13_RS14420LLI13_RS14435LLI13_RS14440LLI13_RS14425LLI13_RS14430LLI13_RS14445LLI13_RS14450
Location: 3236981..3237742 (762 bp)
Type: Others
Protein ID: WP_121546315.1
Location: 3237730..3238500 (771 bp)
Type: Others
Protein ID: WP_121546316.1
Location: 3238512..3238982 (471 bp)
Type: Others
Protein ID: WP_004930328.1
Location: 3239040..3240260 (1221 bp)
Type: Others
Protein ID: WP_121546317.1
Location: 3241517..3241783 (267 bp)
Type: Antitoxin
Protein ID: WP_040908670.1
Location: 3241776..3242042 (267 bp)
Type: Toxin
Protein ID: WP_121546319.1
Location: 3240261..3240536 (276 bp)
Type: Others
Protein ID: WP_121546318.1
Location: 3240617..3241462 (846 bp)
Type: Others
Protein ID: WP_004930321.1
Location: 3242149..3244356 (2208 bp)
Type: Others
Protein ID: WP_121546320.1
Location: 3244457..3245056 (600 bp)
Type: Others
Protein ID: WP_004930314.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
LLI13_RS144053236981..3237742+762WP_121546315.1cobalt ECF transporter T component CbiQ-
LLI13_RS144103237730..3238500+771WP_121546316.1ABC transporter ATP-binding protein-
LLI13_RS144153238512..3238982+471WP_004930328.1MarR family transcriptional regulator-
LLI13_RS144203239040..3240260+1221WP_121546317.1serine hydrolase domain-containing protein-
LLI13_RS144253240261..3240536-276WP_121546318.1DUF1876 domain-containing protein-
LLI13_RS144303240617..3241462-846WP_004930321.1DMT family transporter-
LLI13_RS144353241517..3241783+267WP_040908670.1type II toxin-antitoxin system Phd/YefM family antitoxinAntitoxin
LLI13_RS144403241776..3242042+267WP_121546319.1type II toxin-antitoxin system RelE/ParE family toxinToxin
LLI13_RS144453242149..3244356-2208WP_121546320.1MMPL family transporter-
LLI13_RS144503244457..3245056-600WP_004930314.1TetR/AcrR family transcriptional regulator-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 89 a.a.        Molecular weight: 10199.72 Da        Isoelectric Point: 10.2960

>T222650 WP_121546319.1 NZ_CP086179:3241776-3242042 [Streptomyces fungicidicus]
VSSGYRTVFRPEAQAELRKIPRDMALRILVKLTELETDPLGFRTTALVSRPDRRRLRVGDYRVIYTIDNGELTVWVVHVG
HRSTVYDT

Download         Length: 267 bp

>T222650 NZ_CP117988:c1533373-1533083 [Vibrio campbellii]
ATGACCTATAAACTCGACTTTAAAAAGAGCGCACTCAAAGAGTGGAAAAAGCTTGGCTCTACTCTGCAACAACAATTTAA
GAAAAAGCTAATCGAGCGCTTAGATAATCCACATGTTCCAGCGTCAAAACTTTCTGGAGCTGACAACATGTATAAAATTA
AGTTGCGTCAGTCGGGCTACCGTCTCGTCTACAAAGTCGAAGACGATGTCATCATTGTAACCGTCTTAGCAGTCGGAAAA
CGAGAACGTAGCAATGTTTACCGTAAAGCCATGAAAAGGTTAGATGATTGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10218.61 Da        Isoelectric Point: 4.5329

>AT222650 WP_040908670.1 NZ_CP086179:3241517-3241783 [Streptomyces fungicidicus]
MTEMPIESIRDVRAHLAEVVERADRDDTPTVITRRGKQVAAVVSMEVLRKYQEWEEREINRIIDERMANPAAGIPIEDVM
RETLERGE

Download         Length: 267 bp

>AT222650 NZ_CP117988:c1533611-1533363 [Vibrio campbellii]
ATGACCACTAGAATTTTAGCTGATGTTGCTGCAAGCATTACCGAGTTGAAAGCTAACCCTATGAAAGTTGCAACTAGTGC
TTATGGCGAACCTGTTGCTGTATTAAACCGAAATGAGCCAGCATTTTATTGCGTACCTGCCGAAGCGTACGAAATGATGA
TGGACAGACTCGAAGATCTTGAACTACTAGCTATCGCTAAAGAGCGTGAATCTGAAGAGAGCATTTCGGTAAATATTGAT
GACCTATAA

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
No matching records found


Antitoxin

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Source
ID
Structure
AlphaFold DBA0A7H8J816

References