Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/RelE-Phd |
Location | 3241517..3242042 | Replicon | chromosome |
Accession | NZ_CP086179 | ||
Organism | Streptomyces fungicidicus strain F1 |
Toxin (Protein)
Gene name | relE | Uniprot ID | - |
Locus tag | LLI13_RS14440 | Protein ID | WP_121546319.1 |
Coordinates | 3241776..3242042 (+) | Length | 89 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | A0A7H8J816 |
Locus tag | LLI13_RS14435 | Protein ID | WP_040908670.1 |
Coordinates | 3241517..3241783 (+) | Length | 89 a.a. |
Genomic Context
Location: 3236981..3237742 (762 bp)
Type: Others
Protein ID: WP_121546315.1
Type: Others
Protein ID: WP_121546315.1
Location: 3237730..3238500 (771 bp)
Type: Others
Protein ID: WP_121546316.1
Type: Others
Protein ID: WP_121546316.1
Location: 3238512..3238982 (471 bp)
Type: Others
Protein ID: WP_004930328.1
Type: Others
Protein ID: WP_004930328.1
Location: 3239040..3240260 (1221 bp)
Type: Others
Protein ID: WP_121546317.1
Type: Others
Protein ID: WP_121546317.1
Location: 3241517..3241783 (267 bp)
Type: Antitoxin
Protein ID: WP_040908670.1
Type: Antitoxin
Protein ID: WP_040908670.1
Location: 3241776..3242042 (267 bp)
Type: Toxin
Protein ID: WP_121546319.1
Type: Toxin
Protein ID: WP_121546319.1
Location: 3240261..3240536 (276 bp)
Type: Others
Protein ID: WP_121546318.1
Type: Others
Protein ID: WP_121546318.1
Location: 3240617..3241462 (846 bp)
Type: Others
Protein ID: WP_004930321.1
Type: Others
Protein ID: WP_004930321.1
Location: 3242149..3244356 (2208 bp)
Type: Others
Protein ID: WP_121546320.1
Type: Others
Protein ID: WP_121546320.1
Location: 3244457..3245056 (600 bp)
Type: Others
Protein ID: WP_004930314.1
Type: Others
Protein ID: WP_004930314.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
LLI13_RS14405 | 3236981..3237742 | + | 762 | WP_121546315.1 | cobalt ECF transporter T component CbiQ | - |
LLI13_RS14410 | 3237730..3238500 | + | 771 | WP_121546316.1 | ABC transporter ATP-binding protein | - |
LLI13_RS14415 | 3238512..3238982 | + | 471 | WP_004930328.1 | MarR family transcriptional regulator | - |
LLI13_RS14420 | 3239040..3240260 | + | 1221 | WP_121546317.1 | serine hydrolase domain-containing protein | - |
LLI13_RS14425 | 3240261..3240536 | - | 276 | WP_121546318.1 | DUF1876 domain-containing protein | - |
LLI13_RS14430 | 3240617..3241462 | - | 846 | WP_004930321.1 | DMT family transporter | - |
LLI13_RS14435 | 3241517..3241783 | + | 267 | WP_040908670.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
LLI13_RS14440 | 3241776..3242042 | + | 267 | WP_121546319.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
LLI13_RS14445 | 3242149..3244356 | - | 2208 | WP_121546320.1 | MMPL family transporter | - |
LLI13_RS14450 | 3244457..3245056 | - | 600 | WP_004930314.1 | TetR/AcrR family transcriptional regulator | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
No matching records found |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 89 a.a. Molecular weight: 10199.72 Da Isoelectric Point: 10.2960
>T222650 WP_121546319.1 NZ_CP086179:3241776-3242042 [Streptomyces fungicidicus]
VSSGYRTVFRPEAQAELRKIPRDMALRILVKLTELETDPLGFRTTALVSRPDRRRLRVGDYRVIYTIDNGELTVWVVHVG
HRSTVYDT
VSSGYRTVFRPEAQAELRKIPRDMALRILVKLTELETDPLGFRTTALVSRPDRRRLRVGDYRVIYTIDNGELTVWVVHVG
HRSTVYDT
Download Length: 267 bp
>T222650 NZ_CP117988:c1533373-1533083 [Vibrio campbellii]
ATGACCTATAAACTCGACTTTAAAAAGAGCGCACTCAAAGAGTGGAAAAAGCTTGGCTCTACTCTGCAACAACAATTTAA
GAAAAAGCTAATCGAGCGCTTAGATAATCCACATGTTCCAGCGTCAAAACTTTCTGGAGCTGACAACATGTATAAAATTA
AGTTGCGTCAGTCGGGCTACCGTCTCGTCTACAAAGTCGAAGACGATGTCATCATTGTAACCGTCTTAGCAGTCGGAAAA
CGAGAACGTAGCAATGTTTACCGTAAAGCCATGAAAAGGTTAGATGATTGA
ATGACCTATAAACTCGACTTTAAAAAGAGCGCACTCAAAGAGTGGAAAAAGCTTGGCTCTACTCTGCAACAACAATTTAA
GAAAAAGCTAATCGAGCGCTTAGATAATCCACATGTTCCAGCGTCAAAACTTTCTGGAGCTGACAACATGTATAAAATTA
AGTTGCGTCAGTCGGGCTACCGTCTCGTCTACAAAGTCGAAGACGATGTCATCATTGTAACCGTCTTAGCAGTCGGAAAA
CGAGAACGTAGCAATGTTTACCGTAAAGCCATGAAAAGGTTAGATGATTGA
Antitoxin
Download Length: 89 a.a. Molecular weight: 10218.61 Da Isoelectric Point: 4.5329
>AT222650 WP_040908670.1 NZ_CP086179:3241517-3241783 [Streptomyces fungicidicus]
MTEMPIESIRDVRAHLAEVVERADRDDTPTVITRRGKQVAAVVSMEVLRKYQEWEEREINRIIDERMANPAAGIPIEDVM
RETLERGE
MTEMPIESIRDVRAHLAEVVERADRDDTPTVITRRGKQVAAVVSMEVLRKYQEWEEREINRIIDERMANPAAGIPIEDVM
RETLERGE
Download Length: 267 bp
>AT222650 NZ_CP117988:c1533611-1533363 [Vibrio campbellii]
ATGACCACTAGAATTTTAGCTGATGTTGCTGCAAGCATTACCGAGTTGAAAGCTAACCCTATGAAAGTTGCAACTAGTGC
TTATGGCGAACCTGTTGCTGTATTAAACCGAAATGAGCCAGCATTTTATTGCGTACCTGCCGAAGCGTACGAAATGATGA
TGGACAGACTCGAAGATCTTGAACTACTAGCTATCGCTAAAGAGCGTGAATCTGAAGAGAGCATTTCGGTAAATATTGAT
GACCTATAA
ATGACCACTAGAATTTTAGCTGATGTTGCTGCAAGCATTACCGAGTTGAAAGCTAACCCTATGAAAGTTGCAACTAGTGC
TTATGGCGAACCTGTTGCTGTATTAAACCGAAATGAGCCAGCATTTTATTGCGTACCTGCCGAAGCGTACGAAATGATGA
TGGACAGACTCGAAGATCTTGAACTACTAGCTATCGCTAAAGAGCGTGAATCTGAAGAGAGCATTTCGGTAAATATTGAT
GACCTATAA
Structures
Toxin
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Source | ID | Structure |
---|---|---|
No matching records found |
Antitoxin
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Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A7H8J816 |