Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/Fic(toxin)
Location 2966147..2966712 Replicon chromosome
Accession NZ_CP086177
Organism Streptomyces fungicidicus strain F7

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag LL040_RS13300 Protein ID WP_121546168.1
Coordinates 2966147..2966515 (-) Length 123 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag LL040_RS13305 Protein ID WP_121546169.1
Coordinates 2966515..2966712 (-) Length 66 a.a.

Genomic Context

LL040_RS13280LL040_RS13320LL040_RS13285LL040_RS13290LL040_RS13295LL040_RS13300LL040_RS13305LL040_RS13310LL040_RS13325
Location: 2961223..2962200 (978 bp)
Type: Others
Protein ID: WP_121546166.1
Location: 2968547..2969770 (1224 bp)
Type: Others
Protein ID: WP_228312966.1
Location: 2962197..2962988 (792 bp)
Type: Others
Protein ID: WP_121546167.1
Location: 2963297..2963938 (642 bp)
Type: Others
Protein ID: WP_040907076.1
Location: 2964223..2966022 (1800 bp)
Type: Others
Protein ID: WP_004930870.1
Location: 2966147..2966515 (369 bp)
Type: Toxin
Protein ID: WP_121546168.1
Location: 2966515..2966712 (198 bp)
Type: Antitoxin
Protein ID: WP_121546169.1
Location: 2966745..2968205 (1461 bp)
Type: Others
Protein ID: WP_121546170.1
Location: 2969787..2970965 (1179 bp)
Type: Others
Protein ID: WP_121546172.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
LL040_RS132802961223..2962200+978WP_121546166.1glycine betaine ABC transporter substrate-binding protein-
LL040_RS132852962197..2962988-792WP_121546167.1S16 family serine protease-
LL040_RS132902963297..2963938-642WP_040907076.1helix-turn-helix domain-containing protein-
LL040_RS132952964223..2966022-1800WP_004930870.1DEAD/DEAH box helicase-
LL040_RS133002966147..2966515-369WP_121546168.1Fic family proteinToxin
LL040_RS133052966515..2966712-198WP_121546169.1hypothetical proteinAntitoxin
LL040_RS133102966745..2968205-1461WP_121546170.1MFS transporter-
LL040_RS133202968547..2969770+1224WP_228312966.1hypothetical protein-
LL040_RS133252969787..2970965-1179WP_121546172.1SUKH-4 family immunity protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Fido domain

(4-80)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 123 a.a.        Molecular weight: 13745.67 Da        Isoelectric Point: 4.6413

>T222641 WP_121546168.1 NZ_CP086177:c2966515-2966147 [Streptomyces fungicidicus]
MYYLTLPELLNLAKRLGEDVVRDYGLLDSALARPQSSVFGQDAYPDVWQKAAALMESLARNHALVDGNKRLAWYATWVFL
HMNGHPLDPDFDVDEAEQFVLDVCQGALDVPKIAAQLPRFAR

Download         Length: 369 bp

>T222641 NZ_CP117979:c107227-106961 [Staphylococcus aureus]
ATGAGCAATTACACGGTTAAGATTAAAAATTCGGCGAAGTTAGATTTAAAGAAAATAAAACATCCTTATTTAAAGAAGAC
ATTTATAGAAATTGTTGAGACTTTAAAAAAAAATCCTTATAAAATAACACAATCCTTTGAAAAATTAGAACCTAAATATT
TAGAGCGATATTCAAGAAGAATTAACCTTCAGCACAGGGTCGTCTATACCATAGATGATCGAAATAAAGTAGTATTAATA
CTATCGGCATGGTCACATTATGATTAA

Antitoxin


Download         Length: 66 a.a.        Molecular weight: 7349.21 Da        Isoelectric Point: 5.5900

>AT222641 WP_121546169.1 NZ_CP086177:c2966712-2966515 [Streptomyces fungicidicus]
MAGLNLRFTDEELDALRERAAAEGRSMQTFAHDAVIKAINEHSRLFNEAADHVLRASEELNRRLA

Download         Length: 198 bp

>AT222641 NZ_CP117979:c107484-107227 [Staphylococcus aureus]
ATGATTATCACTAGCCCTACAGAAGCGAGAAAAGATTTTTATCAATTACTAAAAAATGTTAATAATAATCACGAACCAAT
TTATATTAGTGGTAATAATGCCGAAAATAATGCTGTGATTATAGGTTTAGAAGATTGGAAAAGTATACAAGAGACAATGT
ATCTTGTATCTACTGGTACAATGGACAAAGTAAGAGAAAGAGAAAAAGATAATAGTGGTACAACAAATATAGATGATATT
GATTGGGATAATCTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References