Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | phd-doc/Fic(toxin) |
Location | 2965714..2966279 | Replicon | chromosome |
Accession | NZ_CP086175 | ||
Organism | Streptomyces fungicidicus strain F9 |
Toxin (Protein)
Gene name | doc | Uniprot ID | - |
Locus tag | LL042_RS13300 | Protein ID | WP_121546168.1 |
Coordinates | 2965714..2966082 (-) | Length | 123 a.a. |
Antitoxin (Protein)
Gene name | phd | Uniprot ID | - |
Locus tag | LL042_RS13305 | Protein ID | WP_121546169.1 |
Coordinates | 2966082..2966279 (-) | Length | 66 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
LL042_RS13280 | 2960790..2961767 | + | 978 | WP_121546166.1 | glycine betaine ABC transporter substrate-binding protein | - |
LL042_RS13285 | 2961764..2962555 | - | 792 | WP_121546167.1 | S16 family serine protease | - |
LL042_RS13290 | 2962864..2963505 | - | 642 | WP_040907076.1 | helix-turn-helix domain-containing protein | - |
LL042_RS13295 | 2963790..2965589 | - | 1800 | WP_004930870.1 | DEAD/DEAH box helicase | - |
LL042_RS13300 | 2965714..2966082 | - | 369 | WP_121546168.1 | Fic family protein | Toxin |
LL042_RS13305 | 2966082..2966279 | - | 198 | WP_121546169.1 | hypothetical protein | Antitoxin |
LL042_RS13310 | 2966312..2967772 | - | 1461 | WP_121546170.1 | MFS transporter | - |
LL042_RS13320 | 2968114..2969337 | + | 1224 | WP_228312966.1 | hypothetical protein | - |
LL042_RS13325 | 2969354..2970532 | - | 1179 | WP_121546172.1 | SUKH-4 family immunity protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 123 a.a. Molecular weight: 13745.67 Da Isoelectric Point: 4.6413
>T222633 WP_121546168.1 NZ_CP086175:c2966082-2965714 [Streptomyces fungicidicus]
MYYLTLPELLNLAKRLGEDVVRDYGLLDSALARPQSSVFGQDAYPDVWQKAAALMESLARNHALVDGNKRLAWYATWVFL
HMNGHPLDPDFDVDEAEQFVLDVCQGALDVPKIAAQLPRFAR
MYYLTLPELLNLAKRLGEDVVRDYGLLDSALARPQSSVFGQDAYPDVWQKAAALMESLARNHALVDGNKRLAWYATWVFL
HMNGHPLDPDFDVDEAEQFVLDVCQGALDVPKIAAQLPRFAR
Download Length: 369 bp
>T222633 NZ_CP117976:c2509786-2509556 [Salmonella enterica]
ATGAAGGTGTATGGCAGCAATCTCGGAGAACCTCACACCAGCGCCTTTGGTGATGGGCTTTTTGAGCTTCGGATTAAAGG
TAGCGATGGCATCGCTCGCGTTTTTTACTGCACCCTGGCAGGGAAGCGCATCGTCATGCTGCACAGCTTTATAAAGAAGA
CGCAGAAAACCCCTGTAGCTGAACGCAAAAAGGCAGAAACCAGAATGAAGGAGGTTAAGCATGACTGGTAA
ATGAAGGTGTATGGCAGCAATCTCGGAGAACCTCACACCAGCGCCTTTGGTGATGGGCTTTTTGAGCTTCGGATTAAAGG
TAGCGATGGCATCGCTCGCGTTTTTTACTGCACCCTGGCAGGGAAGCGCATCGTCATGCTGCACAGCTTTATAAAGAAGA
CGCAGAAAACCCCTGTAGCTGAACGCAAAAAGGCAGAAACCAGAATGAAGGAGGTTAAGCATGACTGGTAA
Antitoxin
Download Length: 66 a.a. Molecular weight: 7349.21 Da Isoelectric Point: 5.5900
>AT222633 WP_121546169.1 NZ_CP086175:c2966279-2966082 [Streptomyces fungicidicus]
MAGLNLRFTDEELDALRERAAAEGRSMQTFAHDAVIKAINEHSRLFNEAADHVLRASEELNRRLA
MAGLNLRFTDEELDALRERAAAEGRSMQTFAHDAVIKAINEHSRLFNEAADHVLRASEELNRRLA
Download Length: 198 bp
>AT222633 NZ_CP117976:c2509566-2509258 [Salmonella enterica]
ATGACTGGTAAACGTAATGCGCCAACTATAACGCACGATGAAATGGCCGCTAAATGGATGGAAGACCCAGCGTTCAAAGC
TGAATATGACGCCATTGCTGATGAGTTCGCGTTGCTTGACGAAATGCTGGCCGCACGTAAAGAAGCAGGTCTCACCCAGG
CTGAAGTTGCTGAACGGATGGGAACAAAAGCCACTGCTATAACCAGAATGGAAAGCAACCTTGCTGCTGGCGTCAGCGGA
CCATCTTTTACTACGCTGAAAAAGTTCGCACAGGCAACCGGGAAAAAACTCCAGATCCGCTTCGTGTAA
ATGACTGGTAAACGTAATGCGCCAACTATAACGCACGATGAAATGGCCGCTAAATGGATGGAAGACCCAGCGTTCAAAGC
TGAATATGACGCCATTGCTGATGAGTTCGCGTTGCTTGACGAAATGCTGGCCGCACGTAAAGAAGCAGGTCTCACCCAGG
CTGAAGTTGCTGAACGGATGGGAACAAAAGCCACTGCTATAACCAGAATGGAAAGCAACCTTGCTGCTGGCGTCAGCGGA
CCATCTTTTACTACGCTGAAAAAGTTCGCACAGGCAACCGGGAAAAAACTCCAGATCCGCTTCGTGTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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