Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-Phd
Location 2766604..2767307 Replicon chromosome
Accession NZ_CP086136
Organism Bradyrhizobium barranii subsp. barranii strain 144S4

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag J4G43_RS13325 Protein ID WP_208085075.1
Coordinates 2766604..2767029 (-) Length 142 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag J4G43_RS13330 Protein ID WP_208085076.1
Coordinates 2767026..2767307 (-) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J4G43_RS13295 (J4G43_013335) 2762566..2762976 + 411 WP_085398536.1 acyl-CoA thioesterase -
J4G43_RS13300 (J4G43_013340) 2763197..2763388 + 192 WP_028134810.1 hypothetical protein -
J4G43_RS13305 (J4G43_013345) 2763627..2764022 - 396 WP_208085073.1 nuclear transport factor 2 family protein -
J4G43_RS13310 (J4G43_013350) 2764342..2764809 - 468 WP_085398540.1 nuclear transport factor 2 family protein -
J4G43_RS13315 (J4G43_013355) 2764964..2765662 + 699 WP_208085074.1 HAD-IA family hydrolase -
J4G43_RS13320 (J4G43_013360) 2765754..2766599 + 846 WP_014497447.1 DeoR/GlpR family DNA-binding transcription regulator -
J4G43_RS13325 (J4G43_013365) 2766604..2767029 - 426 WP_208085075.1 type II toxin-antitoxin system VapC family toxin Toxin
J4G43_RS13330 (J4G43_013370) 2767026..2767307 - 282 WP_208085076.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
J4G43_RS13335 (J4G43_013375) 2767537..2769087 + 1551 WP_208085077.1 glycerol-3-phosphate dehydrogenase -
J4G43_RS13340 (J4G43_013380) 2769084..2770160 + 1077 WP_208085078.1 ABC transporter ATP-binding protein -
J4G43_RS13345 (J4G43_013385) 2770175..2771260 + 1086 WP_208085079.1 ABC transporter ATP-binding protein -
J4G43_RS13350 (J4G43_013390) 2771260..2772234 + 975 WP_166350160.1 sugar ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-123)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(14-77)


Sequences

Toxin        


Download         Length: 142 a.a.        Molecular weight: 15359.68 Da        Isoelectric Point: 6.4615

>T222617 WP_208085075.1 NZ_CP086136:c2767029-2766604 [Bradyrhizobium barranii subsp. barranii]
VNLLLDTNVLSEVQRPAPSAKVLAWLDTVDEDRAFISVASIAELRCGIALLDDGRRRAALAAWLAHDLPARFAQRILPID
HVVAERWGDLMAQSRRNGVALSVMDGFFAATALANNLTLVTRNVKDFAAFGVPLLNPWSNA

Download         Length: 426 bp

>T222617 NZ_CP117974:701440-702195 [Pseudomonas aeruginosa]
GTGAGCGAGATCTGGCGACAGTGCAAGGGTGAGCGGCATATCCGACCGCTCCAGGGGCGCCTGGTGCGGTTGGTGGAGAG
CCAGGAGCAGGTGGCGACCCTGCAATTGGTCGACACCCTGGAAGAACAGGCGTTGCTCGAGGAACTGCTCGAGTCGAGCA
AGCCGCCGGTGCCGGCGGATGCCGAGCCATTGCATTACCTGTTGAAGACCCCGTTCCGTTATCCGCCCTTGCGCTGGGGG
TCGCGGTTTGGCCGTCGCCACGAGCCAAGCCTGTTCTACGCCGCGTTGAAGCTGGAAACGGCCATGGCCGAAAGCGCGTA
TTACCGTTGCGTCCTGTGGAGTGGCATGGCGGTGCCGCCACCGAGCGGGAGGATTCTGTCCGAGCACGCTTCGTTCGAGG
CGGGCTGGAAGGTGGAGCGGGGAATCCGTCTGCAGGCGCCGCCTTTCTCCGATCACGAGGCTGCGCTGACCGACATCGCC
GACTACCGCGCTCCCCAGGAACTGGGAAGTGCCATGCGCAGCGCCGGGGTGCAGGCATTCGAATACCGTTCGGCGCGTTG
CCCGGAGCGCGGCTGCAATGTCGCCCTGTTCACGCCCGCGGCCTTCACCGAAAAGCGTCCTCGCAACCTGACGCCCTGGC
TGTGCGAAACCACGGCCGGTTACGTGGCCTTCAAGCCGGCGCATGTGCCGGGGTCGCCGAAAATCTTCTCCTGGGAGCTG
TTCCTGGTGGACGGAAAGTTGCCGCATCCGGCGTGA

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10270.46 Da        Isoelectric Point: 5.1409

>AT222617 WP_208085076.1 NZ_CP086136:c2767307-2767026 [Bradyrhizobium barranii subsp. barranii]
MTDRSTTPDSPSTDTWTLANAKARLSEVVDRAQTGPQIITRHGRPNAVVVSADEWARKTARKGTLAEFLLASPLRGADLE
LERVQDEPRDEMP

Download         Length: 282 bp

>AT222617 NZ_CP117974:700937-701305 [Pseudomonas aeruginosa]
ATGAGCGCTCTCATCAAGGAACGTCCCAGCGCCGATGCCGTCCTGGCCAAGGCCGTCCTGGCCGCGCGCGAGCAATTGGG
GCTGACGCAGCTCGAACTGGCCGGCATCGTCGGCGTCGATCGCAGCGCCATCAGCCGCTGGAAGACCCAGGGCCTGCGGG
TGGACAGCAAGACCGGCGAGCTGGCTCTGCTGCTGGTGCGAGTCTATCGCGCACTGTATGCCCTGTTCGGCGGGCAGCAG
GAGGACATGCGCCACTTCCTGCGCACTCCCAACCATCACCTGGCGGGCGAGCCGCTGGCACTGATGGGACAGGTGCAGGG
CCTGGTTCATGTGCTGGAATACCTCGATGCGATCCGCGGCAAGGTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References