Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/ParE-YafN |
| Location | 66557..67092 | Replicon | plasmid pPA_DBM3797_2 |
| Accession | NZ_CP086135 | ||
| Organism | Pantoea agglomerans strain DBM 3797 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | - |
| Locus tag | LKW31_RS21960 | Protein ID | WP_172608109.1 |
| Coordinates | 66805..67092 (+) | Length | 96 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | A0A379LU84 |
| Locus tag | LKW31_RS21955 | Protein ID | WP_022624281.1 |
| Coordinates | 66557..66808 (+) | Length | 84 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LKW31_RS21935 (LKW31_21960) | 62160..62429 | - | 270 | WP_010257103.1 | DUF1471 family periplasmic protein YahO | - |
| LKW31_RS21940 (LKW31_21965) | 62705..63841 | - | 1137 | WP_033786324.1 | HlyD family secretion protein | - |
| LKW31_RS21945 (LKW31_21970) | 63843..64169 | - | 327 | WP_010257107.1 | DUF3302 domain-containing protein | - |
| LKW31_RS21950 (LKW31_21975) | 64764..66416 | + | 1653 | WP_228312812.1 | intermembrane transport protein PqiB | - |
| LKW31_RS21955 (LKW31_21980) | 66557..66808 | + | 252 | WP_022624281.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
| LKW31_RS21960 (LKW31_21985) | 66805..67092 | + | 288 | WP_172608109.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| LKW31_RS21965 (LKW31_21990) | 67362..67652 | - | 291 | WP_010257118.1 | XRE family transcriptional regulator | - |
| LKW31_RS21970 (LKW31_21995) | 67683..67958 | - | 276 | Protein_60 | SAM-dependent DNA methyltransferase | - |
| LKW31_RS21975 (LKW31_22000) | 68115..68327 | + | 213 | Protein_61 | haloacid dehalogenase type II | - |
| LKW31_RS21980 (LKW31_22005) | 68432..68797 | - | 366 | WP_022624285.1 | 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF | - |
| LKW31_RS21985 (LKW31_22010) | 68794..69114 | - | 321 | WP_022624286.1 | 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE | - |
| LKW31_RS21990 (LKW31_22015) | 69114..70781 | - | 1668 | WP_172608110.1 | lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase | - |
| LKW31_RS21995 (LKW31_22020) | 70781..71683 | - | 903 | WP_045139865.1 | 4-deoxy-4-formamido-L-arabinose- phosphoundecaprenol deformylase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Mobilizable plasmid | - | - | 1..182426 | 182426 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 96 a.a. Molecular weight: 11203.11 Da Isoelectric Point: 10.3856
>T222615 WP_172608109.1 NZ_CP086135:66805-67092 [Pantoea agglomerans]
VSYTVKFREEAFKEWQKLDKSLQQQFAKKLKKCCDNPHIPSARLRGIKDCYKIKLRTSGFRLVYQVIDDQLVIAVVAVGK
RERSDVYHLASERMR
VSYTVKFREEAFKEWQKLDKSLQQQFAKKLKKCCDNPHIPSARLRGIKDCYKIKLRTSGFRLVYQVIDDQLVIAVVAVGK
RERSDVYHLASERMR
Download Length: 288 bp
>T222615 NZ_CP117971:4481268-4481525 [Escherichia coli]
ATGAATTTATCCCGTCAGGAACAACATACCTTACACGTTCTCGCTAAAGGTAGACGTATTGCGCACGTCCGCGATTCTTC
AGGCCGCGTCACTTCCGTTGAATGCTACAGCCGCGAAGGGCTGTTGCTGACCGACTGCACGCTCGCCGTCTTCAAAAAAC
TCAAAACCAAAAAACTTATCAAGTCCGTCAATGGCCAGCCCTATCGAATCAACACCACCGAGCTGAATAAAGTTCGCGCT
CAGCTCGATAATCGCTAA
ATGAATTTATCCCGTCAGGAACAACATACCTTACACGTTCTCGCTAAAGGTAGACGTATTGCGCACGTCCGCGATTCTTC
AGGCCGCGTCACTTCCGTTGAATGCTACAGCCGCGAAGGGCTGTTGCTGACCGACTGCACGCTCGCCGTCTTCAAAAAAC
TCAAAACCAAAAAACTTATCAAGTCCGTCAATGGCCAGCCCTATCGAATCAACACCACCGAGCTGAATAAAGTTCGCGCT
CAGCTCGATAATCGCTAA
Antitoxin
Download Length: 84 a.a. Molecular weight: 9081.35 Da Isoelectric Point: 3.9507
>AT222615 WP_022624281.1 NZ_CP086135:66557-66808 [Pantoea agglomerans]
MPNIILSDTSASVSELKKNPMATVSAGDGYPVAILNRNQPAFYCVPAELYEQMLDALDDQELVKLVSERSGQRLLDVDLD
ALL
MPNIILSDTSASVSELKKNPMATVSAGDGYPVAILNRNQPAFYCVPAELYEQMLDALDDQELVKLVSERSGQRLLDVDLD
ALL
Download Length: 252 bp
>AT222615 NZ_CP117971:4481537-4482082 [Escherichia coli]
ATGACAGTACACCACTTCACTTTTCATATCACAGATAAAAGTGATGCCAGTGATATCCGGGAAGTCGAAACCCGCGCATT
TGGCTTTAGCAAAGAAGCCGATTTAGTGACCTCTTTACTTGAGGATGAAAGCGCGCGCCCCGCGTTATCGCTGCTAGCCC
GGTATGAAGGCAAAGCCGTCGGGCATATTTTATTTACCCGGGCAACCTTCAAAGGAGAAATGGATTCACCGTTGATGCAC
ATCCTCGCTCCCCTGGCGGTCATACCGGAATACCAAGGGATGGGCGTGGGAGGACGGTTGATACGCACTGGCATCGAGCA
CCTGAGGTTGATGGGCTGCCAGACGGTTTTTGTTCTCGGCCACGCCACCTATTACCCCCGACATGGGTTCGAACCCTGTG
CCGGAGACAAAGGCTATCCGGCACCTTATCCCATCCCGGAGGAGCACAAAGCCTGCTGGATGATGCAATCACTCACCGCT
CAGCCCATGACCCTGACCGGCCACATCCGGTGCGCAGACCCTGATGAAACCGGAGCACTGACGTGA
ATGACAGTACACCACTTCACTTTTCATATCACAGATAAAAGTGATGCCAGTGATATCCGGGAAGTCGAAACCCGCGCATT
TGGCTTTAGCAAAGAAGCCGATTTAGTGACCTCTTTACTTGAGGATGAAAGCGCGCGCCCCGCGTTATCGCTGCTAGCCC
GGTATGAAGGCAAAGCCGTCGGGCATATTTTATTTACCCGGGCAACCTTCAAAGGAGAAATGGATTCACCGTTGATGCAC
ATCCTCGCTCCCCTGGCGGTCATACCGGAATACCAAGGGATGGGCGTGGGAGGACGGTTGATACGCACTGGCATCGAGCA
CCTGAGGTTGATGGGCTGCCAGACGGTTTTTGTTCTCGGCCACGCCACCTATTACCCCCGACATGGGTTCGAACCCTGTG
CCGGAGACAAAGGCTATCCGGCACCTTATCCCATCCCGGAGGAGCACAAAGCCTGCTGGATGATGCAATCACTCACCGCT
CAGCCCATGACCCTGACCGGCCACATCCGGTGCGCAGACCCTGATGAAACCGGAGCACTGACGTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|