Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 4896697..4897340 Replicon chromosome
Accession NZ_CP086111
Organism Skermanella rosea strain KEMB 2255-458

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag JL101_RS22835 Protein ID WP_228435524.1
Coordinates 4896951..4897340 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag JL101_RS22830 Protein ID WP_203102782.1
Coordinates 4896697..4896936 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JL101_RS22830 (JL101_022875) 4896697..4896936 + 240 WP_203102782.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
JL101_RS22835 (JL101_022880) 4896951..4897340 + 390 WP_228435524.1 type II toxin-antitoxin system VapC family toxin Toxin
JL101_RS22840 (JL101_022885) 4897608..4898075 - 468 WP_228435090.1 transposase -
JL101_RS22845 (JL101_022890) 4898212..4898550 - 339 WP_203102785.1 hypothetical protein -
JL101_RS22850 (JL101_022895) 4898974..4899603 + 630 WP_203102786.1 tail fiber protein -
JL101_RS22855 (JL101_022900) 4899657..4899986 - 330 WP_203102788.1 hypothetical protein -
JL101_RS22860 (JL101_022905) 4900084..4900635 + 552 WP_203102789.1 GNAT family N-acetyltransferase -
JL101_RS22865 (JL101_022910) 4900622..4900921 - 300 WP_203102791.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-121)

Antitoxin

SpoVT-AbrB domain

(11-48)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 13917.16 Da        Isoelectric Point: 7.1074

>T222541 WP_228435524.1 NZ_CP086111:4896951-4897340 [Skermanella rosea]
MLDTNIVSDLIRNPAGKAAHRIMSVGDKALCTSIVVAGELRYGCARKSSPKLTRKVDEILSVIPVLPFDVPADADYGRIR
CELEQAGLSIGGNDLLIAAHAMVLGLTLVTANTREFSRVSGLRVENWLE

Download         Length: 390 bp

>T222541 NZ_CP117960:1678700-1679077 [Escherichia coli]
ATGCAAACCCAACCACTATCCTCAACGCAGGAGGCTACATCACGCCCGTCACCGGTGGAGATCTGGCAACGGCTTCTGAG
CCACCTGTTGGATCGTCACTACGGTCTGACGCTTAACGACACGCCGTTTGGCAACGACGGTGTGATTCAGGAGCATATCG
ACGCCGGTATATCACTGTGCGACGCCGTGAATTTTATTGTGGAGAAGTACGATCTGGTGCGCATCGATCGTCACGGTTTC
AGTACAGAAACACAGTTGCCGCGTCTCACCAGTATCGATATTCTCCGCGCCCGCAAAGCCACCGGGTTGATGACTCGCAA
CGATTACAGAACGGTGACCGACATCACCACCGGTAAATACCGTGGGGGGCATCGATGA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 9094.34 Da        Isoelectric Point: 4.6486

>AT222541 WP_203102782.1 NZ_CP086111:4896697-4896936 [Skermanella rosea]
MQPASRHVRLFRNGRNQAVRIPVEFELPGDEAIMHRDGNRLVLEPVPRHGLLALLATWEPLDEEFPEVTDEPVKPEDVF

Download         Length: 240 bp

>AT222541 NZ_CP117960:1678290-1678649 [Escherichia coli]
TTGTCGAATAAAATACCGACAGTAAACCACGATATCACTGAACCCTGGTGGGGGCTTAAACGCAGTATCACGCCCTGTTT
TGGCGCACGGCTGGTGCAGTCGGGCAACTGTCTGCATTATCTCGCTGACCGGGCCAGCATCACCGGACAGTTCAGCGACG
GGGATTTACGGCATCTCGACCAGGCATTTCCACTGCTGCTCAAACAGCTTGAACTGATGCTCACCAGCGGTGAACTCACT
CCCCGCCATCAGCACTGTGTCACGCTCTATGCAAAAGGGCTGACCTGCGAGGCCGACTCCCTCGGCTCGCATGGTTACGT
ATACCTGGCGATTTATCCGACACCAGCGGCAACCGCGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References