Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 4131808..4132418 Replicon chromosome
Accession NZ_CP086111
Organism Skermanella rosea strain KEMB 2255-458

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag JL101_RS19310 Protein ID WP_228434980.1
Coordinates 4132062..4132418 (+) Length 119 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag JL101_RS19305 Protein ID WP_203097767.1
Coordinates 4131808..4132065 (+) Length 86 a.a.

Genomic Context

JL101_RS19290JL101_RS19295JL101_RS19300JL101_RS19305JL101_RS19310JL101_RS19330JL101_RS19275JL101_RS19280JL101_RS19285JL101_RS19315JL101_RS19320JL101_RS19325JL101_RS19335JL101_RS19340
Location: 4129706..4130791 (1086 bp)
Type: Others
Protein ID: WP_203097769.1
Location: 4130781..4131323 (543 bp)
Type: Others
Protein ID: WP_228434978.1
Location: 4131430..4131732 (303 bp)
Type: Others
Protein ID: WP_203097768.1
Location: 4131808..4132065 (258 bp)
Type: Antitoxin
Protein ID: WP_203097767.1
Location: 4132062..4132418 (357 bp)
Type: Toxin
Protein ID: WP_228434980.1
Location: 4135142..4135324 (183 bp)
Type: Others
Protein ID: WP_203097763.1
Location: 4127586..4128701 (1116 bp)
Type: Others
Protein ID: WP_203097770.1
Location: 4128698..4129165 (468 bp)
Type: Others
Protein ID: WP_203097846.1
Location: 4129308..4129508 (201 bp)
Type: Others
Protein ID: WP_158046558.1
Location: 4132481..4133107 (627 bp)
Type: Others
Protein ID: WP_203097766.1
Location: 4133114..4133818 (705 bp)
Type: Others
Protein ID: WP_203097765.1
Location: 4133978..4134985 (1008 bp)
Type: Others
Protein ID: WP_203097764.1
Location: 4135355..4136071 (717 bp)
Type: Others
Protein ID: WP_203097762.1
Location: 4136089..4136319 (231 bp)
Type: Others
Protein ID: WP_203097761.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
JL101_RS19275 (JL101_019315)4127586..4128701-1116WP_203097770.15-(carboxyamino)imidazole ribonucleotide synthase-
JL101_RS19280 (JL101_019320)4128698..4129165-468WP_203097846.15-(carboxyamino)imidazole ribonucleotide mutase-
JL101_RS19285 (JL101_019325)4129308..4129508-201WP_158046558.1DUF465 domain-containing protein-
JL101_RS19290 (JL101_019330)4129706..4130791+1086WP_203097769.1ATP-dependent 6-phosphofructokinase-
JL101_RS19295 (JL101_019335)4130781..4131323+543WP_228434978.1TIGR02444 family protein-
JL101_RS19300 (JL101_019340)4131430..4131732+303WP_203097768.1hypothetical protein-
JL101_RS19305 (JL101_019345)4131808..4132065+258WP_203097767.1type II toxin-antitoxin system VapB family antitoxinAntitoxin
JL101_RS19310 (JL101_019350)4132062..4132418+357WP_228434980.1type II toxin-antitoxin system VapC family toxinToxin
JL101_RS19315 (JL101_019355)4132481..4133107-627WP_203097766.1UbiX family flavin prenyltransferase-
JL101_RS19320 (JL101_019360)4133114..4133818-705WP_203097765.1DUF1013 domain-containing protein-
JL101_RS19325 (JL101_019365)4133978..4134985-1008WP_203097764.1NAD(P)H-quinone oxidoreductase-
JL101_RS19330 (JL101_019370)4135142..4135324+183WP_203097763.1DUF1192 domain-containing protein-
JL101_RS19335 (JL101_019375)4135355..4136071-717WP_203097762.1DUF599 domain-containing protein-
JL101_RS19340 (JL101_019380)4136089..4136319-231WP_203097761.1ribbon-helix-helix domain-containing protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-114)

Antitoxin

Antitoxin VapB-like

(1-83)


Sequences

Toxin        


Download         Length: 119 a.a.        Molecular weight: 12789.81 Da        Isoelectric Point: 9.7567

>T222540 WP_228434980.1 NZ_CP086111:4132062-4132418 [Skermanella rosea]
MIVDTSAVIAILELEPEAADFAGLIAKAETPWISAVAVVEAGMLADSRRGPAGADELDRFLVRARFQIVPFDHVQARIAR
LAFRRYGKGRHPTSLNLGDCIAYSLSKASGKPLLSKRQ

Download         Length: 357 bp

>T222540 NZ_CP117960:1631247-1631525 [Escherichia coli]
ATGATTCAAAGGGATATTGAATACTCGGGACAATTTTCAAAGGATGTAAAACTTGCACAAAAGCGTCATAAGGATATGAA
TAAATTGAAATATCTTATGACGCTTCTTATCAATAATACTTTACCGCTTCCAGCTGTTTATAAAGACCACCCGCTGCAAG
GTTCATGGAAAGGTTATCGCGATGCTCATGTCGAACCGGACTGGATCCTGATTTACAAACTTACCGATAAACTTTTACGA
TTTGAGAGAACTGGAACTCACGCGGCGCTATTTGGGTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9559.74 Da        Isoelectric Point: 4.5854

>AT222540 WP_203097767.1 NZ_CP086111:4131808-4132065 [Skermanella rosea]
MPLDIKDPEADRLASELARRRGVSVAEAVLAALREQIRREDEKSNSSVTAGELLEIGKRYSSLPILDDRPEEEILGYDQQ
GLPRR

Download         Length: 258 bp

>AT222540 NZ_CP117960:1630984-1631244 [Escherichia coli]
ATGGCTGCTAACGCGTTTGTTCGCGCCCGAATCGATGAAGATCTGAAGAATCAGGCGGCGGACGTACTGGCCGGGATGGG
GCTGACCATCTCTGACCTGGTTCGCATAACCCTCACAAAAGTCGCGCGTGAAAAGGCATTGCCGTTTGATTTACGCGAGC
CTAATCAATTAACCATTCAATCAATTAAAAACAGCGAAGCTGGCGTTGATGTTCATAAGGCCAAAGACGCCGATGATTTA
TTTGATAAATTAGGAATTTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References