Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 3832034..3832613 Replicon chromosome
Accession NZ_CP086111
Organism Skermanella rosea strain KEMB 2255-458

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag JL101_RS17895 Protein ID WP_203097135.1
Coordinates 3832034..3832291 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag JL101_RS17900 Protein ID WP_203097134.1
Coordinates 3832284..3832613 (+) Length 110 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JL101_RS17875 (JL101_017915) 3827220..3828176 + 957 WP_203097138.1 ABC transporter permease -
JL101_RS17880 (JL101_017920) 3828190..3828996 + 807 WP_203097137.1 ABC transporter permease -
JL101_RS17885 (JL101_017925) 3828993..3831065 + 2073 WP_228434928.1 ABC transporter ATP-binding protein -
JL101_RS17890 (JL101_017930) 3831062..3831916 + 855 WP_203097136.1 PhnD/SsuA/transferrin family substrate-binding protein -
JL101_RS17895 (JL101_017935) 3832034..3832291 + 258 WP_203097135.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
JL101_RS17900 (JL101_017940) 3832284..3832613 + 330 WP_203097134.1 helix-turn-helix transcriptional regulator Antitoxin
JL101_RS17905 (JL101_017945) 3832754..3833284 - 531 WP_203097133.1 hypothetical protein -
JL101_RS17910 (JL101_017950) 3833314..3833592 - 279 WP_203097132.1 DUF2934 domain-containing protein -
JL101_RS17915 (JL101_017955) 3833613..3833819 - 207 WP_192499005.1 DUF2795 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-77)

Antitoxin

Cro/C1-type helix-turn-helix domain

(52-106)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9625.10 Da        Isoelectric Point: 10.4249

>T222539 WP_203097135.1 NZ_CP086111:3832034-3832291 [Skermanella rosea]
MQIQYEAQAAKSLRKLPANVRNRIRSKIEQYAQDPTSLANNVIQLTNSDLFRLRVGDHRVIFAIESGIVTIMVVIDVRPR
GAAYD

Download         Length: 258 bp

>T222539 NZ_CP117960:1386264-1386482 [Escherichia coli]
ATGTCCGAAAAACCTTTAACGAAAACCGATTATTTAATGCGTTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGTGT
TATCGAGAAAAATAAATACGAATTATCAGATAATGAACTGGCGGTATTTTACTCAGCCGCAGATCACCGCCTCGCCGAAT
TGACCATGAATAAACTGTACGACAAGATCCCTTCCTCAGTTTGGAAATTTATTCGCTAA

Antitoxin


Download         Length: 110 a.a.        Molecular weight: 12152.74 Da        Isoelectric Point: 4.5749

>AT222539 WP_203097134.1 NZ_CP086111:3832284-3832613 [Skermanella rosea]
MTDTITIPRAEYDALRTRLEDLEDVLAAQTARTGITLPAEFANRIMDGENPIRVWREYRGLGLRELAIRSGLAAGFLSEI
ENGKRVGSIATYRALARSLDTSLDWLADE

Download         Length: 330 bp

>AT222539 NZ_CP117960:1385864-1386238 [Escherichia coli]
ATGGATGAATACTCACCCAAAAGACATGATATCGCACAGCTTAAGTTTCTCTGTGAAACCCTGTATCATGACTGCCTTGC
AAACCTTGAAGAAAGCAATCATGGCTGGGTAAACGACCCAACCTCGGCGATCAACCTCCAGTTGAATGAACTGATTGAGC
ATATTGCGACCTTCGCACTTAATTACAAAATTAAGTATAATGAAGACAATAAGCTCATTGAGCAGATCGACGAATATCTG
GATGACACCTTTATGTTGTTCAGTAGTTATGGTATTAATATGCAGGATCTTCAGAAATGGCGGAAGTCAGGTAATCGACT
ATTCCGTTGTTTTGTCAATGCGACGAAAGAGAATCCTGCGAGTTTATCTTGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References