Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 3281979..3282622 Replicon chromosome
Accession NZ_CP086111
Organism Skermanella rosea strain KEMB 2255-458

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag JL101_RS15215 Protein ID WP_203100463.1
Coordinates 3282233..3282622 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag JL101_RS15210 Protein ID WP_203100462.1
Coordinates 3281979..3282233 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JL101_RS15190 (JL101_015230) 3277186..3278004 + 819 WP_203100460.1 putative photosynthetic complex assembly protein PuhE -
JL101_RS15195 (JL101_015235) 3278004..3279224 + 1221 WP_203100632.1 5-aminolevulinate synthase -
JL101_RS15200 (JL101_015240) 3279345..3279668 - 324 WP_228434848.1 GxxExxY protein -
JL101_RS15205 (JL101_015245) 3279813..3281891 + 2079 WP_203100461.1 prolyl oligopeptidase family serine peptidase -
JL101_RS15210 (JL101_015250) 3281979..3282233 + 255 WP_203100462.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
JL101_RS15215 (JL101_015255) 3282233..3282622 + 390 WP_203100463.1 type II toxin-antitoxin system VapC family toxin Toxin
JL101_RS15220 (JL101_015260) 3282683..3283831 - 1149 WP_203100464.1 photosynthetic reaction center cytochrome PufC -
JL101_RS15225 (JL101_015265) 3283828..3284805 - 978 WP_203100465.1 photosynthetic reaction center subunit M -
JL101_RS15230 (JL101_015270) 3284816..3285640 - 825 WP_202683445.1 photosynthetic reaction center subunit L -
JL101_RS15235 (JL101_015275) 3285753..3285941 - 189 WP_203100466.1 light-harvesting antenna LH1, alpha subunit -
JL101_RS15240 (JL101_015280) 3285951..3286214 - 264 WP_201081429.1 light-harvesting antenna LH1, beta subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-124)

Antitoxin

Antitoxin VapB-like

(1-83)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 14114.22 Da        Isoelectric Point: 5.9081

>T222537 WP_203100463.1 NZ_CP086111:3282233-3282622 [Skermanella rosea]
MVIDTSAILAVLLGEPEAARISEEIGLGTPRLLSAANLLEASMVIETRKGEAAGRELDLFLYRARIEIVPVDQEQAEIAR
IAWRRYGKGRHPAGLNYGDCFAYALAKSRNAPLLFKGNDFAKTDIGQLN

Download         Length: 390 bp

>T222537 NZ_CP117960:580814-580921 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTGGCGGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9333.54 Da        Isoelectric Point: 4.8723

>AT222537 WP_203100462.1 NZ_CP086111:3281979-3282233 [Skermanella rosea]
MPLNIKDPSTEKIVRELAAVTGEAVTTAVRKAAEERLQRVRNDRFGNRLADELMEIGARCSALPDLDTRSADEILGYDEH
GLPR

Download         Length: 255 bp

>AT222537 NZ_CP117960:c580767-580701 [Escherichia coli]
TGTCTGGTTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References