Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 3168103..3168746 Replicon chromosome
Accession NZ_CP086111
Organism Skermanella rosea strain KEMB 2255-458

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag JL101_RS14680 Protein ID WP_203095929.1
Coordinates 3168103..3168498 (-) Length 132 a.a.

Antitoxin (Protein)


Gene name VapB1 Uniprot ID -
Locus tag JL101_RS14685 Protein ID WP_203095931.1
Coordinates 3168510..3168746 (-) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JL101_RS14660 (JL101_014700) 3163994..3164992 + 999 WP_203095923.1 branched-chain amino acid ABC transporter permease -
JL101_RS14665 (JL101_014705) 3164989..3165741 + 753 WP_203095925.1 ABC transporter ATP-binding protein -
JL101_RS14670 (JL101_014710) 3165738..3166409 + 672 WP_228434841.1 ATP-binding cassette domain-containing protein -
JL101_RS14675 (JL101_014715) 3166409..3167980 + 1572 WP_203095927.1 class I adenylate-forming enzyme family protein -
JL101_RS14680 (JL101_014720) 3168103..3168498 - 396 WP_203095929.1 type II toxin-antitoxin system VapC family toxin Toxin
JL101_RS14685 (JL101_014725) 3168510..3168746 - 237 WP_203095931.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
JL101_RS14690 (JL101_014730) 3168830..3169597 - 768 WP_203095933.1 5'-methylthioadenosine/adenosylhomocysteine nucleosidase -
JL101_RS14695 (JL101_014735) 3169662..3172142 + 2481 WP_203095935.1 ligase-associated DNA damage response DEXH box helicase -
JL101_RS14700 (JL101_014740) 3172233..3172928 + 696 WP_203095936.1 ligase-associated DNA damage response endonuclease PdeM -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-112)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 132 a.a.        Molecular weight: 14183.34 Da        Isoelectric Point: 5.6805

>T222536 WP_203095929.1 NZ_CP086111:c3168498-3168103 [Skermanella rosea]
MLDTNICIYLIKKHPPSVGQRFAQCKVGEVVMSAITYAELAYGVSVSGDRMAQNEAALEILVQDIPVMGFDQAAGRAYGP
VRLSAPDRKRDALDKLIATHAIALDVTLVTNNVGDFACYAGLRTENWVVAQ

Download         Length: 396 bp

>T222536 NZ_CP117960:580279-580386 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGGATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8967.02 Da        Isoelectric Point: 4.5141

>AT222536 WP_203095931.1 NZ_CP086111:c3168746-3168510 [Skermanella rosea]
MHITKVFKDGNSQVVRIPSDMAFDRNDMDVEIERVGDELRIRPVARKLDTVMEKFSAFSDDFMAEGRGDNSESERNTL

Download         Length: 237 bp

>AT222536 NZ_CP117960:c580232-580166 [Escherichia coli]
TGTCTGGTTTCAAGATTAGCCCCCGTTTTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References