Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 2474067..2474774 Replicon chromosome
Accession NZ_CP086111
Organism Skermanella rosea strain KEMB 2255-458

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag JL101_RS11320 Protein ID WP_203095156.1
Coordinates 2474067..2474507 (-) Length 147 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag JL101_RS11325 Protein ID WP_203095157.1
Coordinates 2474520..2474774 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JL101_RS11300 (JL101_011335) 2469589..2470905 + 1317 WP_203095152.1 RsmB/NOP family class I SAM-dependent RNA methyltransferase -
JL101_RS11305 (JL101_011340) 2470902..2471462 + 561 WP_203095153.1 GNAT family N-acetyltransferase -
JL101_RS11310 (JL101_011345) 2471453..2472001 + 549 WP_203095154.1 GNAT family N-acetyltransferase -
JL101_RS11315 (JL101_011350) 2472050..2473621 + 1572 WP_201080105.1 glutamine-hydrolyzing GMP synthase -
JL101_RS11320 (JL101_011355) 2474067..2474507 - 441 WP_203095156.1 type II toxin-antitoxin system VapC family toxin Toxin
JL101_RS11325 (JL101_011360) 2474520..2474774 - 255 WP_203095157.1 plasmid stabilization protein Antitoxin
JL101_RS11330 (JL101_011365) 2474822..2474977 + 156 WP_203095158.1 benzoate/H(+) symporter BenE family transporter -
JL101_RS11335 (JL101_011370) 2475026..2475961 - 936 WP_203095159.1 LysR family transcriptional regulator -
JL101_RS11340 (JL101_011375) 2476068..2476874 + 807 WP_203095160.1 SDR family NAD(P)-dependent oxidoreductase -
JL101_RS11345 (JL101_011380) 2476892..2479459 - 2568 WP_203095161.1 DUF2309 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-123)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 147 a.a.        Molecular weight: 15606.73 Da        Isoelectric Point: 4.7040

>T222534 WP_203095156.1 NZ_CP086111:c2474507-2474067 [Skermanella rosea]
MILLDTNVVSEAMTREPHPRVREWLDAQSAETLFLSSITVAELLFGIGALPAGRRKNALAAALDDVLDVFAARILPFDTP
AARRYADLAVKARAAGKGFPTPDGYIASIAAAHGFAVASRDTSAFNAAGLTVIDPWTWIDPDADRE

Download         Length: 441 bp

>T222534 NZ_CP117960:276703-278025 [Escherichia coli]
ATGCCTAAACTTGTCACTTGGATGAACAACCAGCGGGTAGGCGAGTTAACGAAGTTAGCCAACGGCGCGCACACCTTTAA
GTATGCACCGGAGTGGTTAGCAAGCCGTTATGCCAGACCGTTGTCACTTTCGCTGCCATTGCAGAGGGGGAATATCACCT
CTGATGCCGTATTTAACTTCTTCGATAACCTGTTACCCGATAGCCCGATTGTACGTGACCGGATCGTTAAACGTTATCAT
GCCAAATCCAGACAACCGTTTGATTTATTGTCAGAAATAGGGCGAGACAGCGTTGGTGCCGTGACGTTAATACCCGAAGA
CGAAACCGTAACGCATCCGATAATGGCATGGGAAAAGCTTACTGAAGCCAGACTTGAAGAAGTATTAACGGCTTATAAAG
CAGATATCCCGCTAGGCATGATTAGAGAAGAAAATGACTTTCGCATCTCGGTTGCTGGCGCACAGGAGAAGACAGCACTG
CTCAGAATAGGCAATGACTGGTGCATTCCGAAAGGAATAACGCCGACGACGCACATCATTAAATTACCGATTGGCGAAAT
CAGGCAGCCCAATGCGACGCTCGATCTCAGCCAAAGCGTTGATAATGAGTATTACTGTCTGCTGCTGGCGAAAGAACTTG
GGTTGAATGTTCCGGACGCAGAAATCATTAAAGCGGGAAATGTGCGCGCGTTAGCGGTCGAACGTTTTGACAGGCGTTGG
AATGCTGAGCGAACGGTTTTACTTCGCTTGCCACAGGAGGATATGTGTCAGACATTCGGTTTACCTTCATCGGTGAAATA
TGAATCAGATGGAGGCCCAGGCATCGCGCGGATCATGGCTTTTTTGATGGGGTCCAGCGAGGCGCTGAAAGATCGCTATG
ATTTTATGAAATTCCAGGTCTTCCAGTGGTTGATTGGCGCAACGGACGGTCATGCAAAAAACTTCTCCGTATTTATTCAG
GCTGGCGGCAGTTATCGACTCACGCCATTTTACGACATCATTTCAGCATTTCCGGTCCTTGGCGGTACGGGAATACACAT
CAGCGATCTCAAACTGGCAATGGGGCTTAACGCATCCAAAGGCAAAAAAACGGCAATCGATAAAATTTATCCGCGACATT
TTTTGGCGACAGCAAAGGTGCTGAGATTCCCGGAAGTGCAGATGCATGAAATCCTGAGTGACTTTGCCAGAATGATTCCA
GCAGCACTGGATAACGTGAAGACTTCATTACCGACAGATTTTCCGGAGAACGTGGTGACGGCAGTTGAAAGCAATGTGTT
GAGGTTGCATGGACGGTTAAGCCGAGAATACGGTAGTAAGTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9349.72 Da        Isoelectric Point: 7.2054

>AT222534 WP_203095157.1 NZ_CP086111:c2474774-2474520 [Skermanella rosea]
MAAVTIRNLSEEAHRALKVRAAQHNRSAEAEMRAILEAAVRPEGRLLLGTVLREIGQKYDIANADIEAIAQVRDTRPAEP
MKFE

Download         Length: 255 bp

>AT222534 NZ_CP117960:276437-276703 [Escherichia coli]
ATGATGAGCTTTCAGAAGATCTATAGCCCAACGCAATTGGCGAATGCAATGAAACTGGTTCGCCAGCAAAATGGCTGGAC
GCAGAGCGAGCTGGCGAAAAAAATTGGTATTAAGCAGGCGACGATTTCCAATTTCGAAAACAACCCTGACAATACCACGC
TCACGACATTTTTTAAGATTTTACAGTCGCTTGAACTCTCAATGACGCTATGCGACGCGAAAAATGCCTCGCCAGAATCA
ACAGAACAGCAAAATCTGGAGTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References