Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 1342060..1342645 Replicon chromosome
Accession NZ_CP086111
Organism Skermanella rosea strain KEMB 2255-458

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag JL101_RS06300 Protein ID WP_203098883.1
Coordinates 1342060..1342359 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag JL101_RS06305 Protein ID WP_203098882.1
Coordinates 1342346..1342645 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JL101_RS06285 (JL101_006295) 1339415..1340179 + 765 WP_203098885.1 SOS response-associated peptidase -
JL101_RS06290 (JL101_006300) 1340750..1341544 + 795 WP_203098884.1 hypothetical protein -
JL101_RS06300 (JL101_006310) 1342060..1342359 - 300 WP_203098883.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
JL101_RS06305 (JL101_006315) 1342346..1342645 - 300 WP_203098882.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
JL101_RS06310 (JL101_006320) 1343017..1344333 - 1317 WP_203098881.1 short-chain fatty acid transporter -
JL101_RS06315 (JL101_006325) 1344429..1344920 - 492 WP_203098880.1 PIN domain-containing protein -
JL101_RS06320 (JL101_006330) 1344917..1345195 - 279 WP_203098879.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
JL101_RS06325 (JL101_006335) 1345327..1345503 - 177 WP_203098878.1 hypothetical protein -
JL101_RS06330 (JL101_006340) 1345585..1346580 - 996 WP_228435311.1 2-hydroxyacid dehydrogenase -
JL101_RS06335 (JL101_006345) 1346755..1347459 + 705 WP_203098877.1 RraA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(4-57)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11357.99 Da        Isoelectric Point: 7.2015

>T222532 WP_203098883.1 NZ_CP086111:c1342359-1342060 [Skermanella rosea]
VAVLEWRETARADLLAILDYISDDNLDAAQRLKNDIEAKTAKLPEHPKLYRTGRVAGTREMVVRTNYVVVYTEDTRAVTI
LRVLHAAQQWPPVQEWKSV

Download         Length: 300 bp

>T222532 NZ_CP117959:5029156-5029554 [Escherichia coli]
ATGCGGGTATTCAAAACAAAACTTATTCGCCTGCAACTTACAGCAGAGGAACTTGATGCGTTAACGGCGGATTTTATTTC
CTATAAGCGTGACGGTGTTTTGCCAGATATATTTGGTCGCGATGCACTCTACGACGACTCCTTTACCTGGCCATTAATCA
AATTTGAGCGAGTTGCTCATATTCATCTGGCAAATGAGAATAATCCATTTCCGCCACAGTTGCGCCAATTCAGCAGAACG
AATGACGAAGCGCATTTGGTATATTGTCAGGAGGCGTTTGATGAGCAAGCATGGTTGCTCATTGCCATTCTGAAACCTGA
ACCTCATAAACTGGCTCGAGATAACAACCAAATGCATAAAATTGGGAAAATGGCAGAAGCGTTTCGCATGCGTTTTTGA

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10755.33 Da        Isoelectric Point: 6.8803

>AT222532 WP_203098882.1 NZ_CP086111:c1342645-1342346 [Skermanella rosea]
MVAQTSMLHIRVDDKLKADATEKLANVGLTVSDAVRILLTRIAKEGALPIGLTATPEAYDEWFRAKVHEALADTSPAAPH
QHVMDEAQALIDRKRRGGA

Download         Length: 300 bp

>AT222532 NZ_CP117959:5028860-5029153 [Escherichia coli]
ATGCATCGAATTCTCGCTGAAAAATCGGTCAATATCACTGAGTTACGTAAAAACCCAGCTAAATACTTTATTGATCAACC
GGTTGCGGTTCTTTCTAATAATCGCCCCGCAGGATATCTCTTAAGTGCCAGCGCATTCGAAGCGTTAATGGACATGCTTG
CTGAACAAGAGGAGAAAAAGCCCATAAAGGCGCGCTTCCGTCCAAGTGCTGCAAGATTAGAGGAAATTACACGCCGCGCT
GAACAATATCTTAATGATATGACGGATGATGATTTCAATGACTTTAAGGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References