Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 1387023..1387608 Replicon chromosome
Accession NZ_CP086106
Organism Skermanella mucosa strain KEMB 2255-438

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag JL100_RS06420 Protein ID WP_202679909.1
Coordinates 1387023..1387322 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag JL100_RS06425 Protein ID WP_202679910.1
Coordinates 1387309..1387608 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JL100_RS06400 (JL100_006425) 1382498..1383241 + 744 WP_202684793.1 SOS response-associated peptidase -
JL100_RS06405 (JL100_006430) 1383618..1384838 - 1221 WP_201072050.1 IS256 family transposase -
JL100_RS06410 (JL100_006435) 1385713..1386507 + 795 WP_202679908.1 hypothetical protein -
JL100_RS06420 (JL100_006445) 1387023..1387322 - 300 WP_202679909.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
JL100_RS06425 (JL100_006450) 1387309..1387608 - 300 WP_202679910.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
JL100_RS06430 (JL100_006455) 1387808..1388230 - 423 WP_202679911.1 hypothetical protein -
JL100_RS06435 (JL100_006460) 1388371..1389687 - 1317 WP_202679912.1 short-chain fatty acid transporter -
JL100_RS06440 (JL100_006465) 1389970..1390146 - 177 WP_192499307.1 hypothetical protein -
JL100_RS06445 (JL100_006470) 1390228..1391223 - 996 WP_228421102.1 2-hydroxyacid dehydrogenase -
JL100_RS06450 (JL100_006475) 1391675..1392127 + 453 WP_202679913.1 RraA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 1383618..1384838 1220


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-57)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11386.05 Da        Isoelectric Point: 8.4752

>T222524 WP_202679909.1 NZ_CP086106:c1387322-1387023 [Skermanella mucosa]
VAVLEWRETARADLLAILDYISDDNLDAAQRLKNDIEAKTAKLPEHPKLYRTGRVAGTREMVVRTNYVVVYTEDTRAVTI
LRVLHAAQQWPPVREWKSV

Download         Length: 300 bp

>T222524 NZ_CP117959:c3138852-3138556 [Escherichia coli]
ATGGAAAAACGCACACCACATACACGTTTGAGTCAGGTTAAAAAACTTGTCAATGCCGGGCAAGTTCGTACAACACGTAG
TGCCCTGTTAAATGCAGATGAGTTAGGTTTGGATTTTGATGGTATGTGTAATGTTATCATTGGATTATCAGAGAGCGACT
TTTATAAAAGCATGACCACCTACTCTGATCATACTATCTGGCAGGATGTTTACAGACCCAGGCTTGTTACAGGCCAGGTT
TATCTTAAAATTACGGTAATTCATGACGTACTGATCGTCTCGTTTAAGGAGAAGTAA

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10745.29 Da        Isoelectric Point: 6.8803

>AT222524 WP_202679910.1 NZ_CP086106:c1387608-1387309 [Skermanella mucosa]
MAAQTSMLHIRVDDKLKADATEKLANVGLTVSDAVRILLTRIAKEGALPIGLTVTPEAYDEWFRAKVHEALADTSPAASH
QHVMDEAQALIDRKRRGGA

Download         Length: 300 bp

>AT222524 NZ_CP117959:c3138554-3138159 [Escherichia coli]
ATGAAATGTCCGGTTTGCCACCAGGGAGAAATGGTTTCTGGCATTAAAGATATTCCATACACCTTCCGTGGACGAAAAAC
AGTATTGAAAGGTATCCACGGTTTATATTGTGTCCATTGCGAAGAGAGCATCATGAATAAAGAAGAGTCAGATGCTTTCA
TGGCGCAAGTAAAGGCATTTCGGGCTTCGGTGAATGCCGAAACAGTGGCACCTGAATTTATAGTGAAGGTTCGAAAAAAG
CTCTCTCTTACCCAAAAAGAGGCAAGCGAAATTTTTGGGGGAGGTGTAAATGCGTTTTCGCGTTACGAAAAAGGCAATGC
CCAACCTCATCCTTCCACAATCAAACTTTTACGTGTTCTGGATAAGCATCCAGAACTATTGAATGAAATCCGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References