Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 477306..477822 Replicon chromosome
Accession NZ_CP086100
Organism Enterobacter ludwigii strain 196

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LL024_RS02270 Protein ID WP_228176140.1
Coordinates 477538..477822 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LL024_RS02265 Protein ID WP_228176144.1
Coordinates 477306..477548 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LL024_RS02250 (LL024_02255) 473303..474043 + 741 WP_228176148.1 KDGP aldolase family protein -
LL024_RS02255 (LL024_02260) 474162..475298 + 1137 WP_228176146.1 lactonase family protein -
LL024_RS02260 (LL024_02265) 475318..477228 + 1911 WP_050737582.1 PRD domain-containing protein -
LL024_RS02265 (LL024_02270) 477306..477548 + 243 WP_228176144.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
LL024_RS02270 (LL024_02275) 477538..477822 + 285 WP_228176140.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LL024_RS02275 (LL024_02280) 477826..478290 - 465 WP_063157014.1 anaerobic ribonucleoside-triphosphate reductase-activating protein -
LL024_RS02280 (LL024_02285) 478428..480566 - 2139 WP_020885401.1 anaerobic ribonucleoside-triphosphate reductase -
LL024_RS02285 (LL024_02290) 480934..481506 - 573 WP_032681842.1 PTS sugar transporter subunit IIA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-83)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-72)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10948.72 Da        Isoelectric Point: 10.1619

>T222493 WP_228176140.1 NZ_CP086100:477538-477822 [Enterobacter ludwigii]
MSYELVFDPRAFKEWTRPGDTVKNQFKKKLANVLVNPWVESARLHGLPDCDKIKLRSQGYRLVYQVQDNVVTVCVITIGK
REKSAVYHDVNKRL

Download         Length: 285 bp

>T222493 NZ_CP117886:4117321-4117665 [Serratia ureilytica]
ATGTGGCAAGTGGTGACCGTCGAACGATTCGACGACTGGTTTTTGGCGCTGAACAACGCCCAGCAAACAAGCATCCTGGC
GGCGATCTTCAAATTACAGACGTTCGGCCCGCAGTTGGCGCGGCCGCACGCCGATACGCTGCATTTTTCCGAAGCGGCCC
GGCAGTTGAAGGAGTTGCGCGTTCAACATCGCGGGCGCCCTTTCAGGGTGTTTTTCGCCTTTGACCCACAGCGGCAAGCA
GTATTGCTGTGCGGTGGCGATAAAACCGGCGACAAACGCTTTTACCAGCGCATGTTGCCCATCGCTGCCATGAAATTTTC
ACATTATCTGGCAACCCGGAGGTAG

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9110.56 Da        Isoelectric Point: 5.1053

>AT222493 WP_228176144.1 NZ_CP086100:477306-477548 [Enterobacter ludwigii]
MATLNVRLDDKLKNEAYAVLEKLNITPTEAVRLLFQYVAETGHMPVKMVTVSDSEDELIQTVRERLANPQKGIKVRLDEL

Download         Length: 243 bp

>AT222493 NZ_CP117886:4117671-4117973 [Serratia ureilytica]
ATGGCCAAACCGTTATCCCAACTGATCGACAAGCTCGATCCCGCCGTCGTTGCCGCAGCCAGGCAAAAAGCGGACAAGGA
AATTTTCGAACTGCGGCTGGCAATGCTGAGGGAAGAGCTGGCGGTCTCTCAGGTTGAATTGGCGAAGCGGCTCGGTATCA
GCCAACCCTCCGTCGCCAATTTGGAAAAGCGCGGCAGCGAAATAAAGCTGTCGTCGCTCAAACGCTATATCGAGGCGATG
GGCGGCACGCTGTCGCTGGATGTGCAATTGCCCAATGGCCAGCACCGTCGCATGACGCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References