Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 4497310..4497826 Replicon chromosome
Accession NZ_CP086099
Organism Enterobacter ludwigii strain 197

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LL023_RS21400 Protein ID WP_228176140.1
Coordinates 4497310..4497594 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LL023_RS21405 Protein ID WP_228176144.1
Coordinates 4497584..4497826 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LL023_RS21385 (LL023_21435) 4493626..4494198 + 573 WP_032681842.1 PTS sugar transporter subunit IIA -
LL023_RS21390 (LL023_21440) 4494566..4496704 + 2139 WP_020885401.1 anaerobic ribonucleoside-triphosphate reductase -
LL023_RS21395 (LL023_21445) 4496842..4497306 + 465 WP_063157014.1 anaerobic ribonucleoside-triphosphate reductase-activating protein -
LL023_RS21400 (LL023_21450) 4497310..4497594 - 285 WP_228176140.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LL023_RS21405 (LL023_21455) 4497584..4497826 - 243 WP_228176144.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
LL023_RS21410 (LL023_21460) 4497904..4499814 - 1911 WP_050737582.1 PRD domain-containing protein -
LL023_RS21415 (LL023_21465) 4499834..4500970 - 1137 WP_228176146.1 lactonase family protein -
LL023_RS21420 (LL023_21470) 4501089..4501829 - 741 WP_228176148.1 KDGP aldolase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-83)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-72)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10948.72 Da        Isoelectric Point: 10.1619

>T222492 WP_228176140.1 NZ_CP086099:c4497594-4497310 [Enterobacter ludwigii]
MSYELVFDPRAFKEWTRPGDTVKNQFKKKLANVLVNPWVESARLHGLPDCDKIKLRSQGYRLVYQVQDNVVTVCVITIGK
REKSAVYHDVNKRL

Download         Length: 285 bp

>T222492 NZ_CP117886:1966223-1966319 [Serratia ureilytica]
AACAAGCCCTGCATTAAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTAGACCGAATATAGGAATC
GTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9110.56 Da        Isoelectric Point: 5.1053

>AT222492 WP_228176144.1 NZ_CP086099:c4497826-4497584 [Enterobacter ludwigii]
MATLNVRLDDKLKNEAYAVLEKLNITPTEAVRLLFQYVAETGHMPVKMVTVSDSEDELIQTVRERLANPQKGIKVRLDEL

Download         Length: 243 bp

>AT222492 NZ_CP117886:c1966319-1966179 [Serratia ureilytica]
AAAAAAAGACCGAATACGATTCCTATATTCGGTCTAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCAT
TTAATGCAGGGCTTGTTCAGCCGTGCACTTTAAGAGTAGCCTACCGCGCCAGTTTTGCCAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References