222325

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE(toxin)
Location 875384..875909 Replicon chromosome
Accession NZ_CP085962
Organism Campylobacter rectus strain FDAARGOS_1549

Toxin (Protein)


Gene name relE Uniprot ID B9D2N3
Locus tag LK437_RS04295 Protein ID WP_002944901.1
Coordinates 875384..875668 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID B9D2N2
Locus tag LK437_RS04300 Protein ID WP_002944882.1
Coordinates 875658..875909 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LK437_RS04275 (LK437_04275) 870524..872068 + 1545 WP_002944912.1 fatty acid--CoA ligase -
LK437_RS04280 (LK437_04280) 872068..873789 + 1722 WP_002944916.1 ATP-binding protein -
LK437_RS04285 (LK437_04285) 873814..874974 + 1161 WP_002944903.1 hypothetical protein -
LK437_RS04290 (LK437_04290) 875120..875371 + 252 WP_100067273.1 hypothetical protein -
LK437_RS04295 (LK437_04295) 875384..875668 - 285 WP_002944901.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LK437_RS04300 (LK437_04300) 875658..875909 - 252 WP_002944882.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
LK437_RS04305 (LK437_04305) 875999..877834 - 1836 WP_002944862.1 dynamin family protein -
LK437_RS04310 (LK437_04310) 877827..880394 - 2568 WP_002944909.1 dynamin family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(9-77)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11089.93 Da        Isoelectric Point: 9.9155

>T222325 WP_002944901.1 NZ_CP085962:c875668-875384 [Campylobacter rectus]
MSYELEFLPSALKEWQKLDNSVKAQFKKKLAERLENPKVAKDKLRGYENIYKIKLKDAGYRLAYQVKDAQITIIVLVVGR
RENDEAYELLKDRI

Download         Length: 285 bp

>T222325 NZ_CP117811:c2787421-2787167 [Lentisphaera profundi]
ATGAAAATAACATTCTCGACTAAAGCATGGGAAGATTATTTATATTGGCAAAAGCAAGATAAAAAAATCTTAAAACGAAT
CAATCTTTTGATCAAAGATATTGAACGAAACCCAAATGATGGATTAGGAAAGCCTGAGATTTTGAGAAATACACTATCTG
GTTACTGCTCTAGAAGAATTACAGATGAACACAGATTAGTTTATAAAATATTAGACAACAATTTAATTCTAATACAGGCT
AGGCATCATTACTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9022.43 Da        Isoelectric Point: 6.4567

>AT222325 WP_002944882.1 NZ_CP085962:c875909-875658 [Campylobacter rectus]
MQTIQANFTASISELKKSPAQILKQAKGNVVAILNHNVPSAYLVPSAVYEKMIEIIDDYHLNKAVDTALASGEKPVKVSL
DEL

Download         Length: 252 bp

>AT222325 NZ_CP117811:c2787669-2787418 [Lentisphaera profundi]
ATGAATGCAATGACATATACAGAAGCTAGACAAAATCTAGCTAAAACTATGGAGACTGTATGTAACAACCATGATCCAGT
AATCATCACTAGCAAAAGAGAAAGATCTGTTGTTATGATTTCTCTCGAAGATTACAGTGCAATGGAAGAAACAAGTTACT
TACTGCGTAGTCCTAAAAATGCTAAAAGACTACTTGAATCAATTTATGAAATTGAAAATGGCGGTGGTGTAGAACGAGAT
TTAATTGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A6G5QQD3

Antitoxin

Source ID Structure
AlphaFold DB A0A6G5QQA1

References