Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1975668..1975808 Replicon chromosome
Accession NZ_CP085860
Organism Serratia marcescens strain MV-u1-SK1-O

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1975712..1975808 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1975668..1975808 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LKZ96_RS09460 (LKZ96_09470) 1970938..1971333 + 396 WP_025302446.1 RidA family protein -
LKZ96_RS09465 (LKZ96_09475) 1971490..1972443 + 954 WP_025302447.1 prolyl aminopeptidase -
LKZ96_RS09470 (LKZ96_09480) 1972474..1972704 - 231 WP_043141621.1 DNA polymerase III subunit theta -
LKZ96_RS09475 (LKZ96_09485) 1973049..1973567 + 519 WP_025302449.1 non-heme ferritin -
LKZ96_RS09480 (LKZ96_09490) 1973892..1974275 + 384 WP_043141618.1 CopC domain-containing protein YobA -
LKZ96_RS09485 (LKZ96_09495) 1974278..1975159 + 882 WP_213928136.1 copper homeostasis membrane protein CopD -
LKZ96_RS09490 (LKZ96_09500) 1975229..1975570 + 342 WP_089180777.1 YebY family protein -
- 1975668..1975808 - 141 - - Antitoxin
- 1975712..1975808 + 97 - - Toxin
LKZ96_RS09495 (LKZ96_09505) 1976041..1976460 + 420 WP_230201378.1 hypothetical protein -
LKZ96_RS09500 (LKZ96_09510) 1976596..1976946 + 351 WP_025302454.1 DUF4377 domain-containing protein -
LKZ96_RS09505 (LKZ96_09515) 1976985..1977821 - 837 WP_049209429.1 aminoglycoside phosphotransferase family protein -
LKZ96_RS09510 (LKZ96_09520) 1978022..1979221 + 1200 WP_025302456.1 trans-2-enoyl-CoA reductase family protein -
LKZ96_RS09515 (LKZ96_09525) 1979379..1979942 + 564 WP_033642723.1 DUF2975 domain-containing protein -
LKZ96_RS09520 (LKZ96_09530) 1979917..1980165 + 249 WP_165698098.1 helix-turn-helix transcriptional regulator -
LKZ96_RS09525 (LKZ96_09535) 1980393..1980632 + 240 WP_072008265.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 97 bp

>T222175 NZ_CP085860:1975712-1975808 [Serratia marcescens]
AACAAGCCCTGCATTAAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTAGACCGAATATAGGAATC
GTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 141 bp

>AT222175 NZ_CP085860:c1975808-1975668 [Serratia marcescens]
AAAAAAAGACCGAATACGATTCCTATATTCGGTCTAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCAT
TTAATGCAGGGCTTGTTCAGCCGTGCACTTTAAGAGTAGCCTACCGCGCCAGTTTTGCCAG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References