Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | phd-doc/Doc-RelB |
| Location | 4255876..4256462 | Replicon | chromosome |
| Accession | NZ_CP085818 | ||
| Organism | Salmonella enterica subsp. enterica serovar Enteritidis strain Clefairy | ||
Toxin (Protein)
| Gene name | doc | Uniprot ID | A0A3V9X0E4 |
| Locus tag | LJF66_RS20840 | Protein ID | WP_000174964.1 |
| Coordinates | 4255876..4256244 (-) | Length | 123 a.a. |
Antitoxin (Protein)
| Gene name | phd | Uniprot ID | V7IU48 |
| Locus tag | LJF66_RS20845 | Protein ID | WP_001522145.1 |
| Coordinates | 4256241..4256462 (-) | Length | 74 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LJF66_RS20820 (4251395) | 4251395..4252465 | - | 1071 | WP_000907840.1 | sn-glycerol-3-phosphate import ATP-binding protein UgpC | - |
| LJF66_RS20825 (4252467) | 4252467..4253312 | - | 846 | WP_000572196.1 | sn-glycerol-3-phosphate ABC transporter permease UgpE | - |
| LJF66_RS20830 (4253309) | 4253309..4254196 | - | 888 | WP_000099303.1 | sn-glycerol-3-phosphate ABC transporter permease UgpA | - |
| LJF66_RS20835 (4254301) | 4254301..4255617 | - | 1317 | WP_000624755.1 | sn-glycerol-3-phosphate ABC transporter substrate-binding protein UgpB | - |
| LJF66_RS20840 (4255876) | 4255876..4256244 | - | 369 | WP_000174964.1 | type II toxin-antitoxin system death-on-curing family toxin | Toxin |
| LJF66_RS20845 (4256241) | 4256241..4256462 | - | 222 | WP_001522145.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
| LJF66_RS20850 (4256593) | 4256593..4257306 | - | 714 | WP_000416114.1 | high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF | - |
| LJF66_RS20855 (4257308) | 4257308..4258075 | - | 768 | WP_000082080.1 | high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivG | - |
| LJF66_RS20860 (4258072) | 4258072..4259349 | - | 1278 | WP_000803764.1 | branched chain amino acid ABC transporter permease LivM | - |
| LJF66_RS20865 (4259346) | 4259346..4260272 | - | 927 | WP_000003007.1 | high-affinity branched-chain amino acid ABC transporter permease LivH | - |
| LJF66_RS20870 (4260332) | 4260332..4261441 | - | 1110 | WP_000822978.1 | high-affinity branched-chain amino acid ABC transporter substrate-binding protein LivK | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 4250658..4259349 | 8691 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 123 a.a. Molecular weight: 13601.91 Da Isoelectric Point: 6.7252
>T221954 WP_000174964.1 NZ_CP085818:c4256244-4255876 [Salmonella enterica subsp. enterica serovar Enteritidis]
MTLQLISAEEIIQFHDRLLRVTPGVTGMPDPGRAEALMYRVLNQIEYEGVTDVWLLAAMHLLAISRGHIFNDGNKRTALF
ITLLFLKRNGISLAANPDFVDMTVDAAAGRLTLEQIVVRLRA
MTLQLISAEEIIQFHDRLLRVTPGVTGMPDPGRAEALMYRVLNQIEYEGVTDVWLLAAMHLLAISRGHIFNDGNKRTALF
ITLLFLKRNGISLAANPDFVDMTVDAAAGRLTLEQIVVRLRA
Download Length: 369 bp
>T221954 NZ_CP117643:1979476-1979808 [Escherichia albertii]
ATGGACAGAGGAGAAATCTGGCTTGTTTCACTTGACCCTATCGCCGGGCATGAGCAAAGCGGAAAACGCCCGGTGCTTAT
CGTTTCTCCGGCCTCGTTTAACGAGGTCACCCGGTTGCCCGTCATTGTTCCGGTAACCAGCGGTGGGCAATTTGCCCGTA
GCGCGGGTTTTGCGGTTTCGCTGGAGGGCGCTGGCACAAAAACGACGGGGATTATTCGTTGCGATCAGCCCAGAACCATT
GATATGGGAGCACGAAACGGTAAGCGGCTGGAGCGCATACCTGACGGTATCATCAACGAGGTGCTGGCAAGGCTGGAAAC
CATCCTGGCCTGA
ATGGACAGAGGAGAAATCTGGCTTGTTTCACTTGACCCTATCGCCGGGCATGAGCAAAGCGGAAAACGCCCGGTGCTTAT
CGTTTCTCCGGCCTCGTTTAACGAGGTCACCCGGTTGCCCGTCATTGTTCCGGTAACCAGCGGTGGGCAATTTGCCCGTA
GCGCGGGTTTTGCGGTTTCGCTGGAGGGCGCTGGCACAAAAACGACGGGGATTATTCGTTGCGATCAGCCCAGAACCATT
GATATGGGAGCACGAAACGGTAAGCGGCTGGAGCGCATACCTGACGGTATCATCAACGAGGTGCTGGCAAGGCTGGAAAC
CATCCTGGCCTGA
Antitoxin
Download Length: 74 a.a. Molecular weight: 8166.17 Da Isoelectric Point: 5.0775
>AT221954 WP_001522145.1 NZ_CP085818:c4256462-4256241 [Salmonella enterica subsp. enterica serovar Enteritidis]
MRTVNYSEARQNLAEVLESAVTAGPVTITRRGHKSAVIISAEEFERYQTARMDDEFAAIMAVHGNELRELADK
MRTVNYSEARQNLAEVLESAVTAGPVTITRRGHKSAVIISAEEFERYQTARMDDEFAAIMAVHGNELRELADK
Download Length: 222 bp
>AT221954 NZ_CP117643:1979218-1979475 [Escherichia albertii]
ATGTATACCACACGTCTGAAAAAGGTTGGCGGTTCTGTCATGCTGGCTGTTCCGCCCGCCGTGCTGAAAACGCTGGCCCT
GTTGCCGGACAGCGAAGTCGGTGTAACCATCGACAACGGCTGCCTGATTATCGAACCGCAAAAACGACCACGCTATTCAC
TGGCCGAACTGCTGGCGCAATGCGATCCCCATGAAGAAATCAGTGATGAGGAGCGCGAATGGATTGATGCGCCTGCCGCA
GGGAAGGAGATCCTGTAA
ATGTATACCACACGTCTGAAAAAGGTTGGCGGTTCTGTCATGCTGGCTGTTCCGCCCGCCGTGCTGAAAACGCTGGCCCT
GTTGCCGGACAGCGAAGTCGGTGTAACCATCGACAACGGCTGCCTGATTATCGAACCGCAAAAACGACCACGCTATTCAC
TGGCCGAACTGCTGGCGCAATGCGATCCCCATGAAGAAATCAGTGATGAGGAGCGCGAATGGATTGATGCGCCTGCCGCA
GGGAAGGAGATCCTGTAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|