Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 2906970..2907486 Replicon chromosome
Accession NZ_CP085815
Organism Salmonella enterica subsp. enterica serovar Enteritidis strain Slowbro

Toxin (Protein)


Gene name relE Uniprot ID B5R9I9
Locus tag LJF37_RS14325 Protein ID WP_000220582.1
Coordinates 2906970..2907254 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID V7ISI8
Locus tag LJF37_RS14330 Protein ID WP_000212724.1
Coordinates 2907244..2907486 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LJF37_RS14310 (2902181) 2902181..2903833 + 1653 WP_000155048.1 alpha,alpha-phosphotrehalase -
LJF37_RS14315 (2904242) 2904242..2906380 + 2139 WP_000187818.1 anaerobic ribonucleoside-triphosphate reductase -
LJF37_RS14320 (2906502) 2906502..2906966 + 465 WP_001268859.1 anaerobic ribonucleoside-triphosphate reductase-activating protein -
LJF37_RS14325 (2906970) 2906970..2907254 - 285 WP_000220582.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LJF37_RS14330 (2907244) 2907244..2907486 - 243 WP_000212724.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
LJF37_RS14335 (2907564) 2907564..2909477 - 1914 WP_001212142.1 BglG family transcription antiterminator -
LJF37_RS14340 (2909494) 2909494..2910234 - 741 WP_000779259.1 KDGP aldolase family protein -
LJF37_RS14345 (2910231) 2910231..2911349 - 1119 WP_001139169.1 DgaE family pyridoxal phosphate-dependent ammonia lyase -
LJF37_RS14350 (2911333) 2911333..2912466 - 1134 WP_000459957.1 amidohydrolase/deacetylase family metallohydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-83)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-80)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10912.66 Da        Isoelectric Point: 9.6743

>T221869 WP_000220582.1 NZ_CP085815:c2907254-2906970 [Salmonella enterica subsp. enterica serovar Enteritidis]
MTYELEFDPRALKEWHKLGDTVQAQLKKKLADVLLNPRIDSARLNDLPDCYKIKLKSSGYRLVYQVRDDVVIVFVVAVGK
REHSAVYHDANKRL

Download         Length: 285 bp

>T221869 NZ_CP117609:c3946112-3945771 [Escherichia albertii]
ATGAAAATTATTCCTGCAACGACGCTGCGGGCGACGACGTCATATCTGTCGCCTGTCGTGGTCTGGCAAACATTACTGGC
CCGCCTGCTGGAGCAGCACTACGGGCTGAATCTTAATGACACACCATTCAACAATGAAAAGGTGATTCAGGAACACATAG
ACGCCGGGATCACTCTGGTCGATGCCGTCAATTTTCTGGTGGAGAAGTACGAATTGATCCGTATCGACAGGAAAGGATTT
AGCTGGCAGGAACAGACGCCTTATCTTCGTGCGGTCGATATTTTGCGTGCGAGGCAGGCTACAGGTCTGCTGCGTCGCTG
CCATAACACCACGGCACGGTGA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8961.34 Da        Isoelectric Point: 5.0651

>AT221869 WP_000212724.1 NZ_CP085815:c2907486-2907244 [Salmonella enterica subsp. enterica serovar Enteritidis]
MATLNVRLDDKLKNEAYAVLEKLNITPTEAVRLLFQYVAETGRMPVKTVTLSDSEDALIQTVRERLSSPQKGIKVSLDDL

Download         Length: 243 bp

>AT221869 NZ_CP117609:c3946478-3946143 [Escherichia albertii]
ATGCTGCAAAAGGACAAGGTCATGCAACAAGAATGGGGGCTTCCCTGTACCGTAACACCACGCTTCACTGCTCGACTGGT
ACAGGAAAGACATAACCTGCATTACCTGGCTGATCGGGCCGCAATCACCGGGAAATTCAGCTCCCCGGATCTGCTGCATA
TCGACCAGGCTTTTCCGGTGCTGATGAAACAACTGGAGCTGAAACTGGCTGACGATGAACTCTCCGCCTGCCAACAACGT
ACCGTCACACTATACGCCAAAGGACTAACCTGCGAAGCCGATACGCTGGGTTCCTGTGGTTACGTCTATATCGCTATTTA
TCCCACTCAACGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A656ILJ8

Antitoxin

Source ID Structure
AlphaFold DB A0A5H5JRI5

References