221752

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) stbDE/ParE-YafN
Location 1305411..1305933 Replicon chromosome
Accession NZ_CP085810
Organism Salmonella enterica subsp. enterica serovar Schwarzengrund strain Moltres

Toxin (Protein)


Gene name stbE Uniprot ID A0A5J1ICX1
Locus tag LJF42_RS06695 Protein ID WP_000221344.1
Coordinates 1305411..1305695 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name stbD Uniprot ID V1H457
Locus tag LJF42_RS06700 Protein ID WP_000885424.1
Coordinates 1305685..1305933 (-) Length 83 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LJF42_RS06670 (LJF42_06670) 1300415..1301656 - 1242 WP_001095723.1 MFS transporter -
LJF42_RS06675 (LJF42_06675) 1301646..1303154 - 1509 WP_000199421.1 FAD-dependent oxidoreductase -
LJF42_RS06680 (LJF42_06680) 1303199..1303687 + 489 WP_001293633.1 MarR family winged helix-turn-helix transcriptional regulator -
LJF42_RS06685 (LJF42_06685) 1303880..1304959 + 1080 WP_000954705.1 S-adenosylmethionine:tRNA ribosyltransferase-isomerase -
LJF42_RS06690 (LJF42_06690) 1305011..1305292 - 282 Protein_1301 RidA family protein -
LJF42_RS06695 (LJF42_06695) 1305411..1305695 - 285 WP_000221344.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LJF42_RS06700 (LJF42_06700) 1305685..1305933 - 249 WP_000885424.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
LJF42_RS06705 (LJF42_06705) 1306233..1306691 + 459 WP_000381836.1 hypothetical protein -
LJF42_RS06710 (LJF42_06710) 1306685..1307017 + 333 WP_000253166.1 DUF1493 family protein -
LJF42_RS06715 (LJF42_06715) 1307181..1308131 + 951 WP_000941990.1 toll/interleukin-1 receptor domain-containing protein -
LJF42_RS06720 (LJF42_06720) 1308202..1308777 - 576 Protein_1307 helix-turn-helix domain-containing protein -
LJF42_RS06725 (LJF42_06725) 1309192..1310115 - 924 WP_023230780.1 hypothetical protein -
LJF42_RS06730 (LJF42_06730) 1310549..1310764 - 216 WP_001530185.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1303880..1313064 9184


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(6-84)

Antitoxin


No domain identified.



Sequences


Toxin        


Download         Length: 95 a.a.        Molecular weight: 11015.73 Da        Isoelectric Point: 10.5388

>T221752 WP_000221344.1 NZ_CP085810:c1305695-1305411 [Salmonella enterica subsp. enterica serovar Schwarzengrund]
MTYKLAFNESALKEWKKLGHTIQEQFKKKLRERLENPRVPASQLHGRKDQYKIKLRGAGYRLVYSVEDEIITVTVIGVGK
RENDAVYKVTQHRS

Download         Length: 285 bp

>T221752 NZ_CP117583:c2008284-2007880 [Escherichia albertii]
GTGGTCCTGTGGCAATCTGATTTGCGCGTCTCCTGGCGCGCGCAGTGGCTCTCCTTGCTGATTCATGGGCTGGTTGCCGC
TGCTATTTTACTCATGCCCTGGCCGCTAAGTTATACCCCGTTATGGATGGTGTTGCTTTCGCTGGTGGTGTTTGATTGCG
TCCGCAGTCAGCGGCGCATTAATGCTCGTCAGGGGGAGATTCGCCTGTTGATGGATGGGCGTTTACGTTGGCAGGGGCAG
GAGTGGAGCATCGTCAGAGCGCCGTGGATGATTAAAACTGGCATGATGTTGCGTTTACTCTCTGATAGCGGCAAACGTCA
GCACCTGTGGCTGGCAGCCGACAGTATGGATGAAGCTGAATGGCGGGATTTGCGGCGAATTTTGTTACAACAAGAGATAC
AGTGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9090.32 Da        Isoelectric Point: 3.9820

>AT221752 WP_000885424.1 NZ_CP085810:c1305933-1305685 [Salmonella enterica subsp. enterica serovar Schwarzengrund]
MAFQILTTTAASITELKRDPMGTFNAGDGAPVAILNRNEPAFYCVPPALYAHLMDILEDEELGRIIDERANERVIEVNID
DL

Download         Length: 249 bp

>AT221752 NZ_CP117583:c2008531-2008265 [Escherichia albertii]
ATGGACATTAACAATAAAGCCCGCATTCACTGGGCATGCCGCCGTGGTATGCGCGAACTCGATATTTCAATCATGCCGTT
TTTCGAACATGAGTACGATAGCTTAAGCGATGACGAAAAACGCATCTTTATTCGACTGCTGGAATGTGACGATCCCGATT
TATTCAACTGGTTGATGAATCACGGTAAACCGGCCGACGCAGAACTGGAAATGATGGTCCGACTCATCCAGACACGGAAC
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A5J1ICX1


Antitoxin

Source ID Structure
AlphaFold DB A0A5I0WPN5

References