221236

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yfjZ-ypjF/CbtA-CbeA
Location 2972931..2973598 Replicon chromosome
Accession NZ_CP085757
Organism Enterobacter hormaechei strain 54569CZ

Toxin (Protein)


Gene name ypjF Uniprot ID -
Locus tag LJU41_RS14375 Protein ID WP_060579732.1
Coordinates 2972931..2973251 (-) Length 107 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag LJU41_RS14380 Protein ID WP_060579733.1
Coordinates 2973272..2973598 (-) Length 109 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LJU41_RS14330 (LJU41_14330) 2967945..2968826 + 882 WP_032608178.1 helix-turn-helix domain-containing protein -
LJU41_RS14335 (LJU41_14335) 2968875..2969318 + 444 WP_045346041.1 GNAT family N-acetyltransferase -
LJU41_RS14340 (LJU41_14340) 2969351..2969938 - 588 WP_023295690.1 hypothetical protein -
LJU41_RS14345 (LJU41_14345) 2969935..2970300 - 366 WP_072034771.1 DUF2778 domain-containing protein -
LJU41_RS14350 (LJU41_14350) 2970310..2970795 - 486 WP_045895876.1 type VI secretion system tube protein TssD -
LJU41_RS14355 (LJU41_14355) 2971172..2971468 - 297 WP_023323949.1 SymE family type I addiction module toxin -
LJU41_RS14360 (LJU41_14360) 2971597..2971767 + 171 WP_065186978.1 YlcI/YnfO family protein -
LJU41_RS14365 (LJU41_14365) 2971773..2972480 + 708 WP_126542334.1 hypothetical protein -
LJU41_RS14370 (LJU41_14370) 2972543..2972785 + 243 WP_045894635.1 hypothetical protein -
LJU41_RS14375 (LJU41_14375) 2972931..2973251 - 321 WP_060579732.1 TA system toxin CbtA family protein Toxin
LJU41_RS14380 (LJU41_14380) 2973272..2973598 - 327 WP_060579733.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
LJU41_RS14385 (LJU41_14385) 2973611..2974081 - 471 WP_060579734.1 DNA repair protein RadC -
LJU41_RS14390 (LJU41_14390) 2974151..2974972 - 822 WP_060579735.1 DUF932 domain-containing protein -
LJU41_RS14395 (LJU41_14395) 2975415..2975606 - 192 WP_072199593.1 hypothetical protein -
LJU41_RS14400 (LJU41_14400) 2975665..2976504 - 840 WP_060579736.1 hypothetical protein -
LJU41_RS14405 (LJU41_14405) 2976564..2976998 - 435 WP_060579737.1 hypothetical protein -
LJU41_RS14410 (LJU41_14410) 2977307..2978470 - 1164 WP_060579738.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 2954408..2991221 36813


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-98)

Antitoxin

Antitoxin CbeA

(7-107)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12078.85 Da        Isoelectric Point: 4.7440

>T221236 WP_060579732.1 NZ_CP085757:c2973251-2972931 [Enterobacter hormaechei]
MNIQPATTPQAAKPCLSPLAVWQMLLASLLDQHYGLTLNDTPFSDETVIQKHIEAGITLADAVNFLVERYELVRIDQKGY
SVQDQEPWLTYMDVHRAQLKLNVERL

Download         Length: 321 bp

>T221236 NZ_CP117363:c14266-13916 [Salmonella enterica subsp. enterica serovar Dublin]
ATGTGGGTCATCGAGACAACCGACACCTTTGATGAGTGGTTCGATGCTCTGGATGATACCGATAGAGCAAACGTGCTGGC
TTCGATGATGGTGCTGCGAGATAGAGGCCCCATGCTGTCGAGGCCATACGCGGATACTGTTAACGGTTCATCCTACAGCA
ACATGAAAGAGCTTCGGGTCCAAAGCAAAGGAGATCCTATCAGAGCGTTCTTTGCGTTCGATCCAAAGCGTAAGGGGATT
CTTCTCTGCGCCGGTAACAAGACCGGGGACGAGAAAAGGTTTTATGAAGTAATGATCCCAATTGCAGACCGTGAGTTTGC
GGCGCACTTGGATAAATTGAAGAAGGAGTGA

Antitoxin


Download         Length: 109 a.a.        Molecular weight: 12187.90 Da        Isoelectric Point: 6.4729

>AT221236 WP_060579733.1 NZ_CP085757:c2973598-2973272 [Enterobacter hormaechei]
MSLIPAHEWGLKSDIVPRFGARLVQEGNRLHFLADRASLMGNFSDTECFKLNDAFPHFISQMESMLTTGELIPCHHRCVT
LYHNGFTCEADTLGSCGYVYIAVYSTQR

Download         Length: 327 bp

>AT221236 NZ_CP117363:c13911-13609 [Salmonella enterica subsp. enterica serovar Dublin]
ATGGCAAGAACTCTTGACCAAATGCTGGCAACAGAAAAGCCTGAGGTTGTTGCCAAAGCACAGAAAGCGGCCACTGAGAT
GTTACTGAACATCCACTTGGCAGAGCTTCGTGATCGCATGAACCTTACCCAGGGGGAAATTGCTGCATCTCTGGGTGTGA
GACAGCCGACAGTCTCCGAGATGGAAAAACCTGGACGAGATCTCAAGCTGTCGTCCATTAAGCGGTACGTTGAGGCCTCC
GGTGGCAAGCTACGCCTCGATGTTGAACTTCCGGACGGCACCCACTACGGCTTTGCCGTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References