Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 265606..266519 Replicon chromosome
Accession NZ_CP085753
Organism Enterobacter hormaechei strain 57816CZ

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag LJU43_RS01340 Protein ID WP_045142243.1
Coordinates 266046..266519 (+) Length 158 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag LJU43_RS01335 Protein ID WP_023296216.1
Coordinates 265606..266049 (+) Length 148 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LJU43_RS01320 (261413) 261413..263134 + 1722 WP_003858307.1 cysteine/glutathione ABC transporter ATP-binding protein/permease CydC -
LJU43_RS01325 (263180) 263180..263884 + 705 WP_040117448.1 leucyl/phenylalanyl-tRNA--protein transferase -
LJU43_RS01330 (264169) 264169..264387 + 219 WP_002211347.1 translation initiation factor IF-1 -
LJU43_RS01335 (265606) 265606..266049 + 444 WP_023296216.1 DUF2384 domain-containing protein Antitoxin
LJU43_RS01340 (266046) 266046..266519 + 474 WP_045142243.1 RES domain-containing protein Toxin
LJU43_RS01345 (266542) 266542..267096 - 555 WP_045142244.1 type I-F CRISPR-associated endoribonuclease Cas6/Csy4 -
LJU43_RS01350 (267106) 267106..268104 - 999 WP_045142245.1 type I-F CRISPR-associated protein Csy3 -
LJU43_RS01355 (268118) 268118..269053 - 936 WP_045142246.1 type I-F CRISPR-associated protein Csy2 -
LJU43_RS01360 (269050) 269050..270360 - 1311 WP_045142247.1 type I-F CRISPR-associated protein Csy1 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(3-145)

Antitoxin

Antitoxin Xre

(15-147)


Sequences

Toxin        


Download         Length: 158 a.a.        Molecular weight: 17569.93 Da        Isoelectric Point: 5.1018

>T221204 WP_045142243.1 NZ_CP085753:266046-266519 [Enterobacter hormaechei]
MIFYRLVTGRFASEAWSGSGANQYGGRWNHKGHPAVYVSTSISLASLEILVHVRKDTVLNQYQLFSIDIPDDQIDYLDKA
WLPEDWQENPAPVSTMDLGTGWLQANSALALILPSCIIPYENNAILNPLHPAFHKALNSVELMPFNFDTRLAEKTAP

Download         Length: 474 bp

>T221204 NZ_CP117359:358263-358538 [Salmonella enterica subsp. enterica serovar Dublin]
ATGGGGCAAAGGGAAATTGAATATTCGGGACAGTTCCAGAAAGATGTAAAACGGGCACAAAAGCGTCATAAGGATGTCGG
CAAACTTAAAACACTTATGACGCTTCTGATTCACCACCCTTTTCCCCTTCCTGCCATTTATAAAGATCACCCGTTACAAG
GTTCATATAGCGGATACCGGGATGCCCATATTGAGCCTGACTGGATTCTTATTTATAAGATAACGGATGAATGCCTGCGA
TTTGAACGAACAGGAACGCATGCCGATTTATTTTAA

Antitoxin


Download         Length: 148 a.a.        Molecular weight: 16512.81 Da        Isoelectric Point: 6.4819

>AT221204 WP_023296216.1 NZ_CP085753:265606-266049 [Enterobacter hormaechei]
MRTWVPAQRPADNTLWRYAGLPASRGMRLIEYLNQGLPVSVLDNIHEWTDMSKAEILRVTGINERNVARRKSTGRTLTPD
ESERVARFVRVLDAAVDYFGSKEEAWNWLQLPVRGLGNVAPVDLIATETGALEVTDLIGRLEHGVFA

Download         Length: 444 bp

>AT221204 NZ_CP117359:358000-358260 [Salmonella enterica subsp. enterica serovar Dublin]
ATGGCTGCAAATGCGCTTGTTCGTGCCCGTATCGACGAAACGCTGAAGGACCAGGCGGCAGATGTCCTGGCTGAAATGGG
GTTAACCATTTCTGATTTGATACGGATTACACTGACTAAAGTTGCGCGTGAAAAGGCATTGCCTTTTGATTTGCGCATAC
CCAATGAGTTAACGTCACGAACGATAGAAAATAGCGAAGCTGGCGTTGATATTCATAAAGCCAAAGATGCTGATGATTTG
TTTGACCAGTTAGGGATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References