Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2020177..2020321 | Replicon | chromosome |
| Accession | NZ_CP085740 | ||
| Organism | Klebsiella pneumoniae strain 51135CZ | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2020213..2020315 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2020177..2020321 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LJU38_RS09930 (LJU38_09930) | 2015307..2017367 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| LJU38_RS09935 (LJU38_09935) | 2017371..2018030 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| LJU38_RS09940 (LJU38_09940) | 2018109..2018339 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| LJU38_RS09945 (LJU38_09945) | 2018452..2018826 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| LJU38_RS09950 (LJU38_09950) | 2018830..2019699 | + | 870 | WP_020956678.1 | copper homeostasis membrane protein CopD | - |
| LJU38_RS09955 (LJU38_09955) | 2019716..2020054 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 2020177..2020321 | - | 145 | - | - | Antitoxin |
| - | 2020213..2020315 | + | 103 | - | - | Toxin |
| LJU38_RS09960 (LJU38_09960) | 2020448..2020729 | - | 282 | Protein_1944 | tyrosine-type recombinase/integrase | - |
| LJU38_RS27865 | 2020806..2021285 | + | 480 | WP_032419797.1 | lysis protein | - |
| LJU38_RS09975 (LJU38_09975) | 2021740..2021935 | + | 196 | Protein_1946 | DNA polymerase V | - |
| LJU38_RS09980 (LJU38_09980) | 2022074..2023579 | + | 1506 | WP_020956680.1 | hypothetical protein | - |
| LJU38_RS09985 (LJU38_09985) | 2023829..2024257 | - | 429 | WP_032419788.1 | type II toxin-antitoxin system PemK/MazF family toxin | - |
| LJU38_RS09990 (LJU38_09990) | 2024267..2024548 | - | 282 | WP_032419786.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T221147 NZ_CP085740:2020213-2020315 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 145 bp
>AT221147 NZ_CP085740:c2020321-2020177 [Klebsiella pneumoniae]
ACATATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
ACATATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
