Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pemIK/MazF(toxin)
Location 321500..322142 Replicon chromosome
Accession NZ_CP085720
Organism Peribacillus asahii strain KF4

Toxin (Protein)


Gene name pemK Uniprot ID -
Locus tag LIT35_RS01710 Protein ID WP_119118987.1
Coordinates 321792..322142 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag LIT35_RS01705 Protein ID WP_119118988.1
Coordinates 321500..321784 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LIT35_RS01685 (LIT35_01685) 317567..318148 - 582 WP_127758801.1 rhomboid family intramembrane serine protease -
LIT35_RS01690 (LIT35_01690) 318226..318588 + 363 WP_127758802.1 holo-ACP synthase -
LIT35_RS01695 (LIT35_01695) 318900..319910 + 1011 WP_127758803.1 outer membrane lipoprotein carrier protein LolA -
LIT35_RS01700 (LIT35_01700) 320189..321343 + 1155 WP_127762404.1 alanine racemase -
LIT35_RS01705 (LIT35_01705) 321500..321784 + 285 WP_119118988.1 antitoxin endoai Antitoxin
LIT35_RS01710 (LIT35_01710) 321792..322142 + 351 WP_119118987.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
LIT35_RS01715 (LIT35_01715) 322497..324665 + 2169 WP_252283456.1 Tex family protein -
LIT35_RS01720 (LIT35_01720) 324716..324835 - 120 WP_119118989.1 cortex morphogenetic protein CmpA -
LIT35_RS01725 (LIT35_01725) 324925..325386 + 462 WP_127758804.1 SprT family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(1-113)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13000.10 Da        Isoelectric Point: 8.4631

>T221122 WP_119118987.1 NZ_CP085720:321792-322142 [Peribacillus asahii]
IVVKRGDVYFADLSPVVGSEQGGTRPVLILQNDIGNRFSPTVIVAAITAQIQKAKLPTHVEINAKKYGFERDSVILLEQI
RTIDKQRLTDKITYLDETMMQKVNEALQISLGLKEF

Download         Length: 351 bp

>T221122 NZ_CP117346:3736919-3737176 [Salmonella enterica subsp. enterica serovar Dublin]
ATGAATGCCTCCGGCGTCAGCGTCCGCCACATCAACAGCAAAACCCACATGACCACCTATTACTCACAAATCCCCAGCCT
GCATCTTAAGGGCGACTGGCTGGAAGAAGCGGGATTTAAGACCGGGCGCGGCGTCACCGTGAAGATTTCACAGGGGTGTA
TTGTGCTGATGGCGGACAGTAACGAGGAGCAGAAGCTGCGCGAGCAGCTTTATCAGGCTAAACAGGTGGTTAAGGGAATT
AAGGACGTGCTGGTTTAG

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10740.05 Da        Isoelectric Point: 4.7348

>AT221122 WP_119118988.1 NZ_CP085720:321500-321784 [Peribacillus asahii]
VSESGATREIIIRLPQNVLTELDGYASEENVNRSEFIYRATTMYLRKKKEFRESMKRGYIEMAAINLTIASEAFQAEYPE
YEAEHAVERLASGG

Download         Length: 285 bp

>AT221122 NZ_CP117346:c3737094-3736762 [Salmonella enterica subsp. enterica serovar Dublin]
TCCGCCATCAGCACAATACACCCCTGTGAAATCTTCACGGTGACGCCGCGCCCGGTCTTAAATCCCGCTTCTTCCAGCCA
GTCGCCCTTAAGATGCAGGCTGGGGATTTGTGAGTAATAGGTGGTCATGTGGGTTTTGCTGTTGATGTGGCGGACGCTGA
CGCCGGAGGCATTCATATTTGCTGACTAAATAAATTCTTAATTATCCGCCGGATGCTGGCTGATTGTGGAGCTCAGGGTG
AGCGAGTATGGGCGCGACATCCTGGCACTGAGCCCCCCTCTCCCCGGCCAGCTCCGGGCGGTGATGAGCAACCGGCTGCC
GGGGCCGTATTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References