Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pemIK/MazF(toxin)
Location 342491..343133 Replicon chromosome
Accession NZ_CP085714
Organism Peribacillus asahii strain CK1

Toxin (Protein)


Gene name pemK Uniprot ID -
Locus tag LIT37_RS01840 Protein ID WP_119118987.1
Coordinates 342783..343133 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag LIT37_RS01835 Protein ID WP_119118988.1
Coordinates 342491..342775 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LIT37_RS01815 (LIT37_01815) 338560..339141 - 582 WP_252288566.1 rhomboid family intramembrane serine protease -
LIT37_RS01820 (LIT37_01820) 339219..339581 + 363 WP_252288568.1 holo-ACP synthase -
LIT37_RS01825 (LIT37_01825) 339891..340901 + 1011 WP_252288570.1 outer membrane lipoprotein carrier protein LolA -
LIT37_RS01830 (LIT37_01830) 341180..342334 + 1155 WP_252291267.1 alanine racemase -
LIT37_RS01835 (LIT37_01835) 342491..342775 + 285 WP_119118988.1 antitoxin endoai Antitoxin
LIT37_RS01840 (LIT37_01840) 342783..343133 + 351 WP_119118987.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
LIT37_RS01845 (LIT37_01845) 343432..345600 + 2169 WP_252291269.1 Tex family protein -
LIT37_RS01850 (LIT37_01850) 345652..345771 - 120 WP_119118989.1 cortex morphogenetic protein CmpA -
LIT37_RS01855 (LIT37_01855) 345861..346322 + 462 WP_252288572.1 SprT family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(1-113)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13000.10 Da        Isoelectric Point: 8.4631

>T221120 WP_119118987.1 NZ_CP085714:342783-343133 [Peribacillus asahii]
IVVKRGDVYFADLSPVVGSEQGGTRPVLILQNDIGNRFSPTVIVAAITAQIQKAKLPTHVEINAKKYGFERDSVILLEQI
RTIDKQRLTDKITYLDETMMQKVNEALQISLGLKEF

Download         Length: 351 bp

>T221120 NZ_CP117346:c2726136-2726033 [Salmonella enterica subsp. enterica serovar Dublin]
GGCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10740.05 Da        Isoelectric Point: 4.7348

>AT221120 WP_119118988.1 NZ_CP085714:342491-342775 [Peribacillus asahii]
VSESGATREIIIRLPQNVLTELDGYASEENVNRSEFIYRATTMYLRKKKEFRESMKRGYIEMAAINLTIASEAFQAEYPE
YEAEHAVERLASGG

Download         Length: 285 bp

>AT221120 NZ_CP117346:2726031-2726176 [Salmonella enterica subsp. enterica serovar Dublin]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References