Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 882837..883375 Replicon chromosome
Accession NZ_CP085688
Organism Providencia rettgeri strain 06-1619

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LHK11_RS03800 Protein ID WP_140172124.1
Coordinates 883085..883375 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LHK11_RS03795 Protein ID WP_140172123.1
Coordinates 882837..883088 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LHK11_RS03780 (LHK11_03780) 879250..880269 + 1020 WP_004905387.1 erythrose-4-phosphate dehydrogenase -
LHK11_RS03785 (LHK11_03785) 880362..881525 + 1164 WP_004905385.1 phosphoglycerate kinase -
LHK11_RS03790 (LHK11_03790) 881585..882661 + 1077 WP_094962157.1 class II fructose-bisphosphate aldolase -
LHK11_RS03795 (LHK11_03795) 882837..883088 + 252 WP_140172123.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
LHK11_RS03800 (LHK11_03800) 883085..883375 + 291 WP_140172124.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LHK11_RS03805 (LHK11_03805) 883370..883726 - 357 WP_140172125.1 nuclear transport factor 2 family protein -
LHK11_RS03810 (LHK11_03810) 883723..884580 - 858 WP_180359520.1 LysR substrate-binding domain-containing protein -
LHK11_RS03815 (LHK11_03815) 884665..885351 + 687 WP_140172127.1 ankyrin repeat domain-containing protein -
LHK11_RS03820 (LHK11_03820) 885393..885818 + 426 WP_282555705.1 nucleoside deaminase -
LHK11_RS03825 (LHK11_03825) 885815..886996 + 1182 WP_096864804.1 cyanate transporter -
LHK11_RS03830 (LHK11_03830) 887093..887962 + 870 WP_140172129.1 AraC family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-86)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11124.23 Da        Isoelectric Point: 10.7261

>T221056 WP_140172124.1 NZ_CP085688:883085-883375 [Providencia rettgeri]
MTGFYKVKFRDDAAKEWKKLGATIQKQFAKKLKLLIENPHIPSARLSGLQNCYKIKLKASGYRLVYEVVDNQLIIIVVTV
GKRNRNEVYDIAKKRL

Download         Length: 291 bp

>T221056 NZ_CP117337:1064-1345 [Salmonella enterica subsp. enterica serovar Dublin]
ATGACCTATGAACTGGCTTTTGACCGCAGAGCACTGAAGGAATGGCAGAAACTCGGCCACACCATCCGTGAACAATTCAA
AAAGAAACTGGCAGAACGGCTGGAAAATCCACGCGTACCCGCAGCCCGGTTACATGGTCATGCTGATCGCTATAAAATCA
AACTTCGTGCATCTGGCTACAGACTTGTATATCAAGTCATTGATGAGAAAGTCGTTTTACTCGTTATTGCCGTTGGAAGA
AGGGAAAGCAGCGAAGTCTATCAGATCGCAGATTTGCGCTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9336.74 Da        Isoelectric Point: 4.2958

>AT221056 WP_140172123.1 NZ_CP085688:882837-883088 [Providencia rettgeri]
MPRVILSDVTASISELKKNPMATVDSGEGFPVAILNRNKPAFYCVPAEIYENLLEQIEDKELIEIVNARKNQKLVDVDLD
SYL

Download         Length: 252 bp

>AT221056 NZ_CP117337:823-1074 [Salmonella enterica subsp. enterica serovar Dublin]
ATGAGCTATCAAATTCTGACAACCACAGCGGCCAGTATTACTGACCTGAAAAAAAATCCTATGGGAACCGTAGCTGAAGG
TGAAGGGGACGCTGTTGCGATCCTGAACCGAAACGAACCGGCGTTCTATTGCGTTCCACCAAAACTTTACGCCTACTATC
GGGAACTCGCTGAAGATGCTGAGTTAAACGCTGTTGCTGATGAGCGCATGAAAAACCCGGAAATTGTGAAGGTTAACCTG
GATGACCTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References