Detailed information of TA system TA220995

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 4614344..4614879
• Replicon: chromosome
• Accession: NZ_CP085633
• Organism: Pectobacterium brasiliense strain TS20HJ1

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: LJQ72_RS20745
• Protein ID: WP_039557465.1
• Coordinates: 4614592..4614879 (+)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: LJQ72_RS20740
• Protein ID: WP_104213032.1
• Coordinates: 4614344..4614595 (+)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LJQ72_RS20715 (LJQ72_20715)	4609977..4610489	-	513	WP_164671261.1	phenolic acid decarboxylase	-
LJQ72_RS20720 (LJQ72_20720)	4610589..4611461	+	873	WP_227527472.1	LysR family transcriptional regulator	-
LJQ72_RS20725 (LJQ72_20725)	4611505..4612128	-	624	WP_039284934.1	LysE family translocator	-
LJQ72_RS20730 (LJQ72_20730)	4612396..4613151	+	756	WP_227527473.1	thiol:disulfide interchange protein DsbG	-
LJQ72_RS20735 (LJQ72_20735)	4613185..4614090	-	906	WP_039501750.1	siderophore-interacting protein	-
LJQ72_RS20740 (LJQ72_20740)	4614344..4614595	+	252	WP_104213032.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
LJQ72_RS20745 (LJQ72_20745)	4614592..4614879	+	288	WP_039557465.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
LJQ72_RS20750 (LJQ72_20750)	4615007..4616359	-	1353	WP_010296544.1	glutathione-disulfide reductase	-
LJQ72_RS20755 (LJQ72_20755)	4616488..4617330	-	843	WP_227527474.1	23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ	-
LJQ72_RS20760 (LJQ72_20760)	4617610..4617993	-	384	WP_205547220.1	TfoX/Sxy family protein	-
LJQ72_RS20765 (LJQ72_20765)	4618093..4619448	-	1356	WP_227527475.1	alkyl/aryl-sulfatase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-84)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 11075.09 Da
• Isoelectric Point: 10.1076

>T220995 WP_039557465.1 NZ_CP085633:4614592-4614879 [Pectobacterium brasiliense]
MSYSVKFREDALKEWLKLDKTIQQQFAKKLKKCCENPHIPSAKLRGMEDCYKIKLRASGFRLVYEVIDDVLIIAVVAVGK
RERSGVYHLASERMR

Nucleotide

• Length: 288 bp

>T220995 NZ_CP117327:206528-207013 [Salmonella enterica subsp. enterica serovar Saintpaul]
GTGGGACGTGTAACAGCACCAGAACCTTTGTCCGCTTTTCATCAGGTAGCTGAGTTCGTCAGCGGTGAAGCTGTGCTCGA
TGACTGGTTGAAGCAAAAGGGCCTCAAAAACCAGGCTCTCGGAGCGGCCAGAACATTTGTGGTGTGCAAGAAAGACACGA
AGCAAGTAGCCGGTTTTTACTCTCTGGCCACCGGTAGCGTCAACCATACAGAAGCGACAGGCAACCTTCGGCGTAACATG
CCAGATCCCATCCCTGTCATTATACTTGCCCGTCTTGCTGTCGATCTCTCATTCCATGGAAAAGGGCTTGGTGCTGATTT
ACTTCATGATGCAGTGCTTCGTTGCTATCGGGTTGCCGAGAATATTGGTGTACGTGCAATCATGGTTCATGCACTTACCG
AAGAAGCCAAAAATTTCTACATTCACCATGGTTTCAAATCATCACAAACTCAGCAGCGAACATTGTTCCTTAGGCTCCCT
CAATAG

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9131.50 Da
• Isoelectric Point: 4.0637

>AT220995 WP_104213032.1 NZ_CP085633:4614344-4614595 [Pectobacterium brasiliense]
MPNIILSDTTASVSELKKNPMATVNAGDGLPVAILNRNQPAFYCIPADLYEKMLDALDDQELVKLIGERKNQPLVDVDLD
SFL

Nucleotide

• Length: 252 bp

>AT220995 NZ_CP117327:206253-206540 [Salmonella enterica subsp. enterica serovar Saintpaul]
ATGCTATACAAGGGGTGTCTCATGAAATCAGATGTTCAACTTAACCTTAGAGCTAAGGAATCGCAGCGGGCGCTCATTGA
TGCAGCTGCGGAAATCCTTCACAAGTCACGTACAGATTTCATTCTGGAAACGGCCTGCCAGGCTGCCGAGAAAGTGATCC
TTGACCGCCGTGTATTTAACTTTAACGATGAGCAATATGAGGAGTTCATCAATCTGCTTGATGCACCGGTCGCAGATGAT
CCCGTTATCGAAAAACTGCTGGCAAGGAAACCTCAGTGGGACGTGTAA