Detailed information of TA system TA220994

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): sdenTA/AbiEii(toxin)
• Location: 4536544..4537984
• Replicon: chromosome
• Accession: NZ_CP085633
• Organism: Pectobacterium brasiliense strain TS20HJ1

Toxin (Protein)

• Gene name: sdenT
• Uniprot ID: -
• Locus tag: LJQ72_RS20390
• Protein ID: WP_039498425.1
• Coordinates: 4536544..4537431 (-)
• Length: 296 a.a.

Antitoxin (Protein)

• Gene name: sdenA
• Uniprot ID: -
• Locus tag: LJQ72_RS20395
• Protein ID: WP_039521884.1
• Coordinates: 4537460..4537984 (-)
• Length: 175 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LJQ72_RS20370 (LJQ72_20370)	4532529..4533350	+	822	WP_227528331.1	M55 family metallopeptidase	-
LJQ72_RS20375 (LJQ72_20375)	4533409..4534356	+	948	WP_180790867.1	isoaspartyl peptidase/L-asparaginase	-
LJQ72_RS20380 (LJQ72_20380)	4534569..4535477	+	909	WP_205569310.1	LysR family transcriptional regulator	-
LJQ72_RS20385 (LJQ72_20385)	4535576..4536439	+	864	WP_227527439.1	YicC/YloC family endoribonuclease	-
LJQ72_RS20390 (LJQ72_20390)	4536544..4537431	-	888	WP_039498425.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
LJQ72_RS20395 (LJQ72_20395)	4537460..4537984	-	525	WP_039521884.1	hypothetical protein	Antitoxin
LJQ72_RS20400 (LJQ72_20400)	4538316..4540805	-	2490	WP_227527440.1	restriction endonuclease-like protein	-
LJQ72_RS20405 (LJQ72_20405)	4540824..4542797	-	1974	WP_227527441.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (39-271)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 296 a.a.
• Molecular weight: 34285.33 Da
• Isoelectric Point: 6.3970

>T220994 WP_039498425.1 NZ_CP085633:c4537431-4536544 [Pectobacterium brasiliense]
MLKQQIRQIVQSNPDYAAVTPVIEKEILHHDIIDVLIKQGVMQRLTFIGGTSLRMCYNSSRLSEDLDFNGGHDFKPSAFE
GLESEIQTYIQNKYETEVWVNKPSGERQGDTVSWKISIVKEANRPDLPRQKMHIDVCAIPSFDIEKRPLINHYDIVVPTE
GILVPVQSLQETLADKLIALAYRARRIKPRDIWDIVWIKQRGIDLSKTLVEKKLTARHKQTDDFRQALSIQLAKLMLQDE
VRDDFNMEMSRFIPKQIKERTLDNPEYWDYVQREVHAITSELLNDVTPKNPFDMG

Nucleotide

• Length: 888 bp

>T220994 NZ_CP117326:4585325-4585636 [Salmonella enterica subsp. enterica serovar Newport]
GTGCATGTTATCAGCCGAAAACCGTTCAATGAAGCGATGCTCATGTATCCAAACCATGAGCTTGCTCTCACTGAGTTGCT
GAATGTTCTTGAGAAAAAAACATTCACTCAGCCTGAAGAGATGAAGCGGTATATTCCTTCACTGGATAATTTTAAGTACA
GAGATAAATGGTGGGTGATTGATGTTTCTGGTAACAGCCTGAGACTCATTTCCTACATAGATTTCAGGTTACATAAGATA
TTTGTGAAACATATCGTTTCCCATGCCGAATATGACAAACTGACCGCATATTATCGGGGTAATAAAGAATGA

Antitoxin

Protein

• Length: 175 a.a.
• Molecular weight: 19432.52 Da
• Isoelectric Point: 9.0504

>AT220994 WP_039521884.1 NZ_CP085633:c4537984-4537460 [Pectobacterium brasiliense]
MTKSDELLNVFSKAVNAGGGIHSATELAFMQGVPCDSAFRKFLADCVKKGLLRRVVKGFYESVITPPEPETAIYKIIKKL
RSGVLNYISLESQLSHTGDISQVVMGRVTVVTKGRSGCFDTPYGVIEFTHTKKPVEQVAPNLYYDPDIKMYRAYKEQAIA
DLKHCQRNLHMLES

Nucleotide

• Length: 525 bp

>AT220994 NZ_CP117326:4585633-4586079 [Salmonella enterica subsp. enterica serovar Newport]
ATGAGAACTCATCGTCAGATGGATGCAACCAGCGCAAAAAAGATCGTTGATACCTTCAGCGATGCGGTAAAAACCGTCCC
ACTGATGGGGGAAGACCGAAATGACAATGAGTATCGCAGGGCACTAGCGCTAGTGGAGTTTCTGGTCGACCACGACGATC
TTGAAAACCCACTATTTGAATTGCTCTGTGCCCGAATCAGTGAATACGAAAAACATGCGCCGGAATTCAAAGCACTCAAC
CAACACCTGGAGAAAACGCCCCCTGGCGTTTCAGTATTGCGAACGCTCATGGATCAATACGGTCTCAAAGCAGCAGATCT
TGCCAACGAACTTGGTTCTAAATCGAACGTCAGCAACATCTTAAATGGCCGCAGAGCACTAACGGTTAATCATATTAAAG
CGCTTACACAACGCTTCAAACTACCAGCAGATGCCTTCATCGAGTAG