Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | tad-ata/COG5606-COG4679 |
| Location | 3315626..3316289 | Replicon | chromosome |
| Accession | NZ_CP085633 | ||
| Organism | Pectobacterium brasiliense strain TS20HJ1 | ||
Toxin (Protein)
| Gene name | tad | Uniprot ID | - |
| Locus tag | LJQ72_RS14940 | Protein ID | WP_205566357.1 |
| Coordinates | 3315626..3315970 (+) | Length | 115 a.a. |
Antitoxin (Protein)
| Gene name | ata | Uniprot ID | - |
| Locus tag | LJQ72_RS14945 | Protein ID | WP_014916192.1 |
| Coordinates | 3315972..3316289 (+) | Length | 106 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LJQ72_RS14915 (LJQ72_14915) | 3310798..3311106 | - | 309 | WP_039498505.1 | YciI family protein | - |
| LJQ72_RS14920 (LJQ72_14920) | 3311146..3311766 | - | 621 | WP_039515522.1 | FMN-dependent NADH-azoreductase | - |
| LJQ72_RS14925 (LJQ72_14925) | 3311801..3312574 | - | 774 | WP_205558785.1 | alpha/beta hydrolase | - |
| LJQ72_RS14930 (LJQ72_14930) | 3312740..3313768 | + | 1029 | WP_227527085.1 | helix-turn-helix domain-containing protein | - |
| LJQ72_RS14935 (LJQ72_14935) | 3313874..3315331 | + | 1458 | WP_040034714.1 | tetratricopeptide repeat protein | - |
| LJQ72_RS14940 (LJQ72_14940) | 3315626..3315970 | + | 345 | WP_205566357.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| LJQ72_RS14945 (LJQ72_14945) | 3315972..3316289 | + | 318 | WP_014916192.1 | helix-turn-helix transcriptional regulator | Antitoxin |
| LJQ72_RS14950 (LJQ72_14950) | 3316377..3316592 | - | 216 | WP_010279992.1 | helix-turn-helix transcriptional regulator | - |
| LJQ72_RS14955 (LJQ72_14955) | 3316699..3316929 | + | 231 | WP_227527086.1 | helix-turn-helix transcriptional regulator | - |
| LJQ72_RS14960 (LJQ72_14960) | 3317012..3317230 | + | 219 | WP_227527087.1 | helix-turn-helix transcriptional regulator | - |
| LJQ72_RS14965 (LJQ72_14965) | 3317305..3318162 | + | 858 | WP_227527088.1 | hypothetical protein | - |
| LJQ72_RS14970 (LJQ72_14970) | 3318447..3318938 | - | 492 | WP_039498513.1 | GNAT family N-acetyltransferase | - |
| LJQ72_RS14975 (LJQ72_14975) | 3318942..3319211 | - | 270 | WP_039498514.1 | DUF1778 domain-containing protein | - |
| LJQ72_RS14980 (LJQ72_14980) | 3319562..3320140 | + | 579 | WP_227527089.1 | transposase domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | flank | IS/Tn | - | - | 3319562..3320140 | 578 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 115 a.a. Molecular weight: 12371.08 Da Isoelectric Point: 9.7991
>T220992 WP_205566357.1 NZ_CP085633:3315626-3315970 [Pectobacterium brasiliense]
MKSLYWVGSSKKDLQSLPADVQDVFGYALHVAQTGGKHTQARPLKGFGGAGVLEVVEDYIGDTYRAVYTVKFGEAVYVLH
AFQKKSSSGIATPKPDMNTIRERLKAAENHAKGA
MKSLYWVGSSKKDLQSLPADVQDVFGYALHVAQTGGKHTQARPLKGFGGAGVLEVVEDYIGDTYRAVYTVKFGEAVYVLH
AFQKKSSSGIATPKPDMNTIRERLKAAENHAKGA
Download Length: 345 bp
>T220992 NZ_CP117326:c4263689-4263198 [Salmonella enterica subsp. enterica serovar Newport]
ATGATCTCCTCCCCTGAGCCGCTTCATGCCGGACATATTCTTACTCCGTTTTGCTGCGGTGTGGATTCTATGGATAACTG
GCTGAAACAGCGGGCGATGAAAAATCAGACCACTGGTGCGTCCCGTACCTTTGTGTGTTGTGGCAGCGATTCGAGCGTAC
TGGCCTATTACTCGCTGGCGTCCAGCGCGGTCACGACGAATACCGCCCCCGGTCGCTTTCGTCGCAATATGCCTGACCCG
ATTCCGATTGTGGTATTGGGGCGTCTGGCGGTGGATAAATCGCTTCATGGGCAGGGCGTTGGTCGGGCGCTGGTACGCGA
CGCAGGGCTGCGGGTTATTCAAGTGGCGGAGACTATCGGCATTCGCGGGATGCTGGTTCACGCCCTGTCGGATGAAGCGC
GGGAATTTTACCAGCGGGTGGGGTTTGTACCGTCGCCGATGGATCCGATGATGTTGATGGTGACGTTGGGGGATTTGGTG
GAGAGTGTTTAA
ATGATCTCCTCCCCTGAGCCGCTTCATGCCGGACATATTCTTACTCCGTTTTGCTGCGGTGTGGATTCTATGGATAACTG
GCTGAAACAGCGGGCGATGAAAAATCAGACCACTGGTGCGTCCCGTACCTTTGTGTGTTGTGGCAGCGATTCGAGCGTAC
TGGCCTATTACTCGCTGGCGTCCAGCGCGGTCACGACGAATACCGCCCCCGGTCGCTTTCGTCGCAATATGCCTGACCCG
ATTCCGATTGTGGTATTGGGGCGTCTGGCGGTGGATAAATCGCTTCATGGGCAGGGCGTTGGTCGGGCGCTGGTACGCGA
CGCAGGGCTGCGGGTTATTCAAGTGGCGGAGACTATCGGCATTCGCGGGATGCTGGTTCACGCCCTGTCGGATGAAGCGC
GGGAATTTTACCAGCGGGTGGGGTTTGTACCGTCGCCGATGGATCCGATGATGTTGATGGTGACGTTGGGGGATTTGGTG
GAGAGTGTTTAA
Antitoxin
Download Length: 106 a.a. Molecular weight: 11434.45 Da Isoelectric Point: 10.6133
>AT220992 WP_014916192.1 NZ_CP085633:3315972-3316289 [Pectobacterium brasiliense]
MSQDIEVSSGNVYADLGNVHAEDMLVKAQLATLISSIIKSRRLTQAEAAKLLGMPQPKLSNLLRGQFRGISETKMLECLT
KLGRDIQIVVGKPRRTPGSVKVVFA
MSQDIEVSSGNVYADLGNVHAEDMLVKAQLATLISSIIKSRRLTQAEAAKLLGMPQPKLSNLLRGQFRGISETKMLECLT
KLGRDIQIVVGKPRRTPGSVKVVFA
Download Length: 318 bp
>AT220992 NZ_CP117326:c4263979-4263686 [Salmonella enterica subsp. enterica serovar Newport]
ATGCCAGCCGCAAACAGTATGGCGATGAAACGCGAAACCCTGAACCTGCGTATCAAACCCGCCGAGCGCGATCTTATTGA
TCGAGCGGCGAAAGCCAGAGGGAAAAACCGCACTGACTTTGTGCTGGAAGCTGCCCGTGCTGCCGCCGAGGAAGCGCTGA
TCGAACAACGCATCATTATGGCCGATCCAGAGGCCTATCAGGAATTTCTGGCTCGTTTGGATCAAACACCTTCACCTAAT
GCCGCACTGCGTAAAACCATGCAGACCCCTGCGCCGTGGGAGCAGGAAAAATGA
ATGCCAGCCGCAAACAGTATGGCGATGAAACGCGAAACCCTGAACCTGCGTATCAAACCCGCCGAGCGCGATCTTATTGA
TCGAGCGGCGAAAGCCAGAGGGAAAAACCGCACTGACTTTGTGCTGGAAGCTGCCCGTGCTGCCGCCGAGGAAGCGCTGA
TCGAACAACGCATCATTATGGCCGATCCAGAGGCCTATCAGGAATTTCTGGCTCGTTTGGATCAAACACCTTCACCTAAT
GCCGCACTGCGTAAAACCATGCAGACCCCTGCGCCGTGGGAGCAGGAAAAATGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|