Detailed information of TA system TA220984

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): mosAT/AbiEii-AbiEi
• Location: 562472..564170
• Replicon: chromosome
• Accession: NZ_CP085633
• Organism: Pectobacterium brasiliense strain TS20HJ1

Toxin (Protein)

• Gene name: mosT
• Uniprot ID: -
• Locus tag: LJQ72_RS02500
• Protein ID: WP_227527658.1
• Coordinates: 562472..563401 (-)
• Length: 310 a.a.

Antitoxin (Protein)

• Gene name: mosA
• Uniprot ID: -
• Locus tag: LJQ72_RS02505
• Protein ID: WP_227527659.1
• Coordinates: 563388..564170 (-)
• Length: 261 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LJQ72_RS02485 (LJQ72_02485)	559771..560598	+	828	WP_227527657.1	alpha/beta hydrolase	-
LJQ72_RS02490 (LJQ72_02490)	560794..561057	-	264	WP_012773200.1	DUF2798 domain-containing protein	-
LJQ72_RS02495 (LJQ72_02495)	561186..562088	+	903	WP_205568942.1	LysR family transcriptional regulator	-
LJQ72_RS02500 (LJQ72_02500)	562472..563401	-	930	WP_227527658.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
LJQ72_RS02505 (LJQ72_02505)	563388..564170	-	783	WP_227527659.1	type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein	Antitoxin
LJQ72_RS02510 (LJQ72_02510)	564517..564657	+	141	Protein_484	helix-turn-helix domain-containing protein	-
LJQ72_RS02515 (LJQ72_02515)	564720..566036	-	1317	WP_227527660.1	IS4 family transposase	-
LJQ72_RS02520 (LJQ72_02520)	566648..568144	+	1497	WP_072036230.1	DUF3375 domain-containing protein	-
LJQ72_RS02525 (LJQ72_02525)	568150..568899	+	750	WP_039515093.1	DUF4194 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	564720..566036	1316

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (14-227)

Antitoxin

• Transcriptional regulator AbiEi antitoxin, N-terminal domain (2-92)

Sequences

Toxin

Protein

• Length: 310 a.a.
• Molecular weight: 35147.50 Da
• Isoelectric Point: 5.4040

>T220984 WP_227527658.1 NZ_CP085633:c563401-562472 [Pectobacterium brasiliense]
MDQRDIYARQVKLLMTALPYVVKEPCFALKGGTAINLFVQDFPRLSVDIDLVYQTFIDRDTDLIAIDDALMRITESLNGR
QGITAIQQENKADEKRIIVNTADAQIKIEVSPVWRGLLLPPTEMPVCEQVEMEYGFTTMSVVSLADLYGGKICAALDRQH
PRDLFDVLNMLEKPCLTREIFDGFLCYLAGHPRPIAELLAPNWDTSRIATLYAQEFSGMTQQETSLESLLSVATLLPQAL
KSHFTAQDWQFLLSYKQNNPDWSLYRYPDIQHLPAIRWKQRNLSALHAKNPAKFSAAVGKLEKVLEQHF

Nucleotide

• Length: 930 bp

>T220984 NZ_CP117326:323663-324031 [Salmonella enterica subsp. enterica serovar Newport]
ATGACCCTACAACTTATCTCAGCGGAAGAGATAATTCAGTTTCACGACAGGCTTCTCCGCGTTACGCCTGGTGTAACAGG
CATGCCTGATCCTGGCCGCGCGGAAGCGCTAATGTATCGGGTACTCAATCAAATCGAATATGAAGGGGTGACCGACGTGT
GGCTGCTGGCGGCAATGCATTTGCTCACTATATCCCGTGGGTATATCTTCAATGATGGTAACAAACGCACCGCCTTATTT
ATTACGCTGCTGTTTTTAAAGCGTAACGGGATCTCACTCGCTGCGAATCCGGATTTTGTCGATATGACAGTCGATGCGGC
GGCAGGGCGGCTTACGCTGGAACAAATTGCCGTTCGCTTACGTGCCTGA

Antitoxin

Protein

• Length: 261 a.a.
• Molecular weight: 29284.63 Da
• Isoelectric Point: 9.4769

>AT220984 WP_227527659.1 NZ_CP085633:c564170-563388 [Pectobacterium brasiliense]
MTNYLNWLMQNTLPGQVLLQSWLTRNGIDRKLSYVYVQNGWLRRIAHGVYCRTGREPDWVDAVYCLQTQWEKPVRVAGLT
SLALQGYSHYTELGKPQIWLTLPAYIKLPGWFTAFKPSATFVVLYTSGLSVDVMPFTTELRIGDRRLTGSVPELAAYEIA
SGVPAQISFEHADALFQGLNLLSPRKLQALLSASHSVKTNRVMLYLAQRNGHPYFQYLDKSGIETGAGKRQIIPGGWLEP
DYQITVPREFKSKGIEDGSA

Nucleotide

• Length: 783 bp

>AT220984 NZ_CP117326:323445-323666 [Salmonella enterica subsp. enterica serovar Newport]
ATGCGTACGGTTAACTATAGCGAAGCGCGGCAAAATCTGGCCGAAGTCCTGGAAAGCGCGGTAACGGCGGGCCCTGTTAC
CATCACGCGTCGTGGGCATAAGTCCGCAGTGATCATCAGCGCCGAGGAGTTTGAGCGTTATCAGACGGCGCGAATGGATG
ATGAGTTTGCTGCCATTATGGCGGTTCATGGCAATGAGCTCAGGAAGCTGGCGGATAAATGA