220983

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 473414..473997 Replicon chromosome
Accession NZ_CP085633
Organism Pectobacterium brasiliense strain TS20HJ1

Toxin (Protein)


Gene name parE Uniprot ID A0A7V8QAI8
Locus tag LJQ72_RS02165 Protein ID WP_012822278.1
Coordinates 473692..473997 (+) Length 102 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A7V8TMU0
Locus tag LJQ72_RS02160 Protein ID WP_012822277.1
Coordinates 473414..473704 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LJQ72_RS02140 (LJQ72_02140) 468548..469810 - 1263 WP_227527628.1 L-rhamnose isomerase -
LJQ72_RS02145 (LJQ72_02145) 469807..471297 - 1491 WP_227527629.1 rhamnulokinase -
LJQ72_RS02150 (LJQ72_02150) 471634..472473 + 840 WP_014913998.1 HTH-type transcriptional activator RhaS -
LJQ72_RS02155 (LJQ72_02155) 472498..473352 + 855 WP_039282583.1 helix-turn-helix domain-containing protein -
LJQ72_RS02160 (LJQ72_02160) 473414..473704 + 291 WP_012822277.1 ribbon-helix-helix protein, CopG family Antitoxin
LJQ72_RS02165 (LJQ72_02165) 473692..473997 + 306 WP_012822278.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LJQ72_RS02170 (LJQ72_02170) 474057..475766 - 1710 WP_227527630.1 ABC transporter ATP-binding protein -
LJQ72_RS02175 (LJQ72_02175) 475763..476629 - 867 WP_227527631.1 ABC transporter permease -
LJQ72_RS02180 (LJQ72_02180) 476622..477581 - 960 WP_039279295.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-96)

Antitoxin

Ribbon-helix-helix protein, CopG

(9-46)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11634.48 Da        Isoelectric Point: 9.4590

>T220983 WP_012822278.1 NZ_CP085633:473692-473997 [Pectobacterium brasiliense]
MPQVIVSERARRDLQRLQDFLKNKNALAAKKAAEVLIRGIRQLEALPNIGRPVEHLPLEYQELVIEFGSSGYVMLYRHDE
LTDRVVILTVKHQKEAGYQNP

Download         Length: 306 bp

>T220983 NZ_CP117322:4652662-4652973 [Salmonella enterica subsp. enterica serovar Derby]
GTGCATGTTATCAGCCGAAAACCGTTCAATGAAGCGATGCTCATGTATCCAAACCATGAGCTTGCCCTCACTGAGTTGCT
GAATGTTCTTGAGAAAAAAACATTCACTCAGCCTGAAGAGATGAAGCGGTATATTCCTTCACTGGATAATTTTAAGTACA
GAGATAAATGGTGGGTGATTGATGTTTCTGGTAACAGCCTGAAACTCATTTCCTACATAGATTTCAGGTTACATAAGATA
TTTGTGAAACATATCGTTTCCCATGCCGAATATGACAAACTGACCGCATACTATCGAGGTAATAAAGAATGA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 11097.16 Da        Isoelectric Point: 4.7845

>AT220983 WP_012822277.1 NZ_CP085633:473414-473704 [Pectobacterium brasiliense]
MADTPRQTTTLRIDQDIKERLKTLADDRHSSAHALMLEAIAEYVEREEKRSQYRKEALAAWEEYQNTGEHITADETVTWL
ESWGSGHEQDAPACHK

Download         Length: 291 bp

>AT220983 NZ_CP117322:4652970-4653416 [Salmonella enterica subsp. enterica serovar Derby]
ATGAGAACTCATCGCCAGATGGATGCAACCAGCGCAAAAAAGATCGTTGATACCTTCAGCGATGCGGTAAAAACCGTCCC
ACTGATGGGGGAAGACCGAAATGACAATGAGTATCGCAGGGCACTAGCGCTAGTGGAGTTTCTGGTCGACCACGACGATC
TTGAAAACCCACTATTTGAATTGCTCTGTGCCCGAATCAGTGAATACGAAAAACATGCGCCGGAATTCAAAGCACTCAAC
CAACACCTGGAGAAAACGCCCCCTGGCGTTTCAGTATTGCGAACGCTCATGGATCAATACGGTCTCAAAGCAGCAGATCT
TGCCAACGAACTTGGTTCTAAATCGAACGTCAGCAACATCTTAAATGGCCGCAGAGCACTAACGGTTAATCATATCAAAG
CGCTTACACAACGCTTTAAACTACCAGCGGATGCCTTCATCGAGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7V8QAI8

Antitoxin

Source ID Structure
AlphaFold DB A0A7V8TMU0

References