Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 4038686..4039346 Replicon chromosome
Accession NZ_CP085627
Organism Erwinia rhapontici strain BY21311

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag LJN55_RS18620 Protein ID WP_159337897.1
Coordinates 4038686..4039099 (-) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag LJN55_RS18625 Protein ID WP_133846122.1
Coordinates 4039080..4039346 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LJN55_RS18600 (LJN55_18600) 4034514..4035032 + 519 WP_227536411.1 flavodoxin FldB -
LJN55_RS18605 (LJN55_18605) 4035129..4036490 - 1362 WP_227535024.1 cell envelope integrity protein CreD -
LJN55_RS18610 (LJN55_18610) 4036580..4037998 - 1419 WP_133846119.1 two-component system sensor histidine kinase CreC -
LJN55_RS18615 (LJN55_18615) 4037998..4038693 - 696 WP_133846120.1 two-component system response regulator CreB -
LJN55_RS18620 (LJN55_18620) 4038686..4039099 - 414 WP_159337897.1 protein YgfX Toxin
LJN55_RS18625 (LJN55_18625) 4039080..4039346 - 267 WP_133846122.1 FAD assembly factor SdhE Antitoxin
LJN55_RS18630 (LJN55_18630) 4039573..4040559 + 987 WP_212813250.1 tRNA-modifying protein YgfZ -
LJN55_RS18635 (LJN55_18635) 4040571..4041224 - 654 WP_133846124.1 hemolysin III family protein -
LJN55_RS18640 (LJN55_18640) 4041437..4042045 + 609 WP_227535025.1 HD domain-containing protein -
LJN55_RS18645 (LJN55_18645) 4042116..4042838 - 723 WP_133846126.1 class I SAM-dependent methyltransferase -
LJN55_RS18650 (LJN55_18650) 4042884..4043639 + 756 WP_227535026.1 hydroxyacylglutathione hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-130)

Antitoxin

Flavinator of succinate dehydrogenase

(8-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16244.17 Da        Isoelectric Point: 11.8917

>T220976 WP_159337897.1 NZ_CP085627:c4039099-4038686 [Erwinia rhapontici]
VVRWRCNLRASRRAQTLSLVLHGTLILALLLAPWPDSVSLPRILLLLLVLLECQCSRHRIRHCRGEITLHKGRVIVWAQC
QWRMTSRPWLTQRAIRLTLQNTAGRRERLWLFADGMDSSEWRLLRQHLLNEKEPRDE

Download         Length: 414 bp

>T220976 NZ_CP117322:c2681543-2681440 [Salmonella enterica subsp. enterica serovar Derby]
GGCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10414.85 Da        Isoelectric Point: 4.6290

>AT220976 WP_133846122.1 NZ_CP085627:c4039346-4039080 [Erwinia rhapontici]
MDISNKSRIHWACRRGMRELDISIMPFFQYEFDSLTDEDKQLFVRLLESDDPDLFNWLMNHGEPADAELQRMVALIQDRN
RARGPVAM

Download         Length: 267 bp

>AT220976 NZ_CP117322:2681438-2681581 [Salmonella enterica subsp. enterica serovar Derby]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References