Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 3064949..3065475 Replicon chromosome
Accession NZ_CP085627
Organism Erwinia rhapontici strain BY21311

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag LJN55_RS14335 Protein ID WP_133841673.1
Coordinates 3065170..3065475 (+) Length 102 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID -
Locus tag LJN55_RS14330 Protein ID WP_227534684.1
Coordinates 3064949..3065167 (+) Length 73 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LJN55_RS14310 (LJN55_14310) 3060321..3062135 - 1815 WP_227534682.1 hypothetical protein -
LJN55_RS14315 (LJN55_14315) 3062192..3062707 - 516 WP_085396429.1 hypothetical protein -
LJN55_RS14320 (LJN55_14320) 3062704..3063888 - 1185 WP_227534683.1 restriction endonuclease -
LJN55_RS14325 (LJN55_14325) 3064560..3064811 - 252 WP_159336428.1 hypothetical protein -
LJN55_RS14330 (LJN55_14330) 3064949..3065167 + 219 WP_227534684.1 type II toxin-antitoxin system antitoxin CcdA Antitoxin
LJN55_RS14335 (LJN55_14335) 3065170..3065475 + 306 WP_133841673.1 type II toxin-antitoxin system toxin CcdB Toxin
LJN55_RS14340 (LJN55_14340) 3066120..3067508 - 1389 WP_227534685.1 ATP-binding protein -
LJN55_RS14345 (LJN55_14345) 3067508..3068185 - 678 WP_227534686.1 response regulator -
LJN55_RS14350 (LJN55_14350) 3068390..3069226 + 837 WP_227534687.1 MipA/OmpV family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-100)

Antitoxin

Post-segregation antitoxin CcdA

(2-72)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11670.63 Da        Isoelectric Point: 6.8688

>T220975 WP_133841673.1 NZ_CP085627:3065170-3065475 [Erwinia rhapontici]
MQFIVYQYKRTSHYKIFVDVQSDIVDTPGRRMVIPLIESHHLSEKVNKTLFPLILIEGKNHRLMTTELSSVPVEVIGDAV
VDITRCQDDIKNAINLMFWGI

Download         Length: 306 bp

>T220975 NZ_CP117322:c2325185-2324901 [Salmonella enterica subsp. enterica serovar Derby]
ATGACTTATAAGCTGGCATTTAACGAATCAGCACTAAAAGAGTGGAAAAAACTGGGTCATACCATACAGGAACAGTTTAA
AAAAAAGCTAAGGGAACGGCTTGAAAACCCTCGGGTTCCGGCTTCTCAATTACATGGAAGAAAGGATCAGTACAAAATTA
AGCTGCGTGGTGCAGGATACAGACTGGTGTACAGCGTCGAAGATGAAATTATCACGGTAACTGTCATTGGTGTTGGAAAG
CGTGAAAATGATGCCGTCTACAAAATGACACGACACAGAAGCTAA

Antitoxin


Download         Length: 73 a.a.        Molecular weight: 8191.16 Da        Isoelectric Point: 5.8395

>AT220975 WP_227534684.1 NZ_CP085627:3064949-3065167 [Erwinia rhapontici]
MKHRVSVTVDKENYLVLNAAGVNISGLVNDVIGREARRIKAEEWKEQNREGMEEVASFIAKNGSFADENRNW

Download         Length: 219 bp

>AT220975 NZ_CP117322:c2325423-2325175 [Salmonella enterica subsp. enterica serovar Derby]
ATGGCATTTCAAATTTTAACGACTACTGCAGCAAGCATTACAGAACTGAAACGTGATCCAATGGGAACTTTCAATGCCGG
AGATGGCGCTCCAGTTGCCATTCTTAACCGTAATGAACCGGCTTTCTACTGTGTGCCTCCGGCACTTTATGCTCATCTTA
TGGATATTCTTGAGGATGAAGAACTCGGTCGTATTATCGATGAGCGTGCGAATGAACGCGTCATTGAGGTCAACATTGAT
GACTTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References