220970

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 254027..254738 Replicon chromosome
Accession NZ_CP085627
Organism Erwinia rhapontici strain BY21311

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LJN55_RS01070 Protein ID WP_227535519.1
Coordinates 254027..254416 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LJN55_RS01075 Protein ID WP_227535521.1
Coordinates 254409..254738 (+) Length 110 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LJN55_RS01055 (LJN55_01055) 250108..250962 + 855 WP_159337736.1 alpha/beta hydrolase -
LJN55_RS01060 (LJN55_01060) 251251..252069 - 819 WP_133844415.1 alpha/beta hydrolase -
LJN55_RS23895 252240..252365 + 126 WP_259152251.1 hypothetical protein -
LJN55_RS01065 (LJN55_01065) 252368..253945 + 1578 WP_227535518.1 MFS transporter -
LJN55_RS01070 (LJN55_01070) 254027..254416 + 390 WP_227535519.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LJN55_RS01075 (LJN55_01075) 254409..254738 + 330 WP_227535521.1 helix-turn-helix domain-containing protein Antitoxin
LJN55_RS01080 (LJN55_01080) 254813..255340 - 528 WP_227535523.1 MarR family transcriptional regulator -
LJN55_RS01085 (LJN55_01085) 255403..256275 + 873 WP_133844409.1 EamA family transporter -
LJN55_RS01090 (LJN55_01090) 256318..257226 - 909 WP_227535525.1 LysR family transcriptional regulator -
LJN55_RS01095 (LJN55_01095) 257357..257998 + 642 WP_133844405.1 hydrolase -
LJN55_RS01100 (LJN55_01100) 258039..258623 + 585 WP_200642554.1 antibiotic biosynthesis monooxygenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(3-125)

Antitoxin

Cro/C1-type helix-turn-helix domain

(50-96)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 14901.99 Da        Isoelectric Point: 7.7929

>T220970 WP_227535519.1 NZ_CP085627:254027-254416 [Erwinia rhapontici]
MPTYMTPEFDRDRKRFRISDQKLCKAADLVRNGAHDGHLGRSVYKKRIGVAGSGASNGARSIIFFSHGDHLYFFDIYVKS
ELSKKKGKELEMDEIESYCDVAQDFLKMNDYLRQQLIKVKELIEVNCDD

Download         Length: 390 bp

>T220970 NZ_CP117318:2224-2499 [Salmonella enterica subsp. enterica serovar Derby]
ATGGAACTGAAGTGGACCAGTAAGGCGCTTTCTGATTTGGCGCGGTTATATGATTTTCTGGTGCTGGCCAGTAAACCTGC
TGCCGCCAGAACGGTACAGTCCCTGACACAGGCACCGGTCATTCTGTTAACTCATCCACGTATGGGAGAACAGTTGTTTC
AGTTTGAACCCAGGGAGGTCAGACGGATTTTTGCTGGCGAGTACGAAATCCGTTACGAACTTAATGACCAGACTATTTAT
GTATTGCGCCTGTGGCACACACGAGAAAACAGGTAG

Antitoxin


Download         Length: 110 a.a.        Molecular weight: 12406.43 Da        Isoelectric Point: 10.7204

>AT220970 WP_227535521.1 NZ_CP085627:254409-254738 [Erwinia rhapontici]
MTERLKRLQGMANRYNKLGVVSDETVARVDARIKARQLRERLPKIRCMDGMQIKSLRIRYGLSQADLAMTLGMSIESVSK
WERNESQPGNAALRILNTIETKGPEVFAE

Download         Length: 330 bp

>AT220970 NZ_CP117318:1940-2224 [Salmonella enterica subsp. enterica serovar Derby]
ATGCAAATGAAAAACAATACCGCACAGGCAACAAAAGTAATTACCGCGCATGTGCCATTACCTATGGCTGATAAAGTCGA
CCAGATGGCCGCCAGGCTGGAACGCTCCCGGGGCTGGGTTATCAAACAGGCGCTTTCTGCATGGCTTGCCCAGGAGGAGG
AGCGTAATCGCCTGACGCTGGAAGCCCTGGACGATGTGACATCCGGACAGGTTATCGACCATCAGGCTGTACAGGCCTGG
GCGGACAGCCTCAGTACTGACAATCCGTTACCGGTGCCACGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References