Detailed information of TA system TA022095

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-Phd
• Location: 1662727..1663265
• Replicon: chromosome
• Accession: NC_009483
• Organism: Geobacter uraniireducens Rf4

Toxin (Protein)

• Gene name: relE
• Uniprot ID: A5G9X3
• Locus tag: GURA_RS07245
• Protein ID: WP_011938341.1
• Coordinates: 1662969..1663265 (+)
• Length: 99 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: GURA_RS07240
• Protein ID: WP_198134537.1
• Coordinates: 1662727..1662972 (+)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
GURA_RS07230	1659071..1660300	+	1230	WP_011938338.1	nucleotidyltransferase	-
GURA_RS07235	1660594..1662561	+	1968	WP_011938339.1	cache domain-containing protein	-
GURA_RS07240	1662727..1662972	+	246	WP_198134537.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
GURA_RS07245	1662969..1663265	+	297	WP_011938341.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
GURA_RS07250	1663391..1663717	+	327	WP_011938342.1	hypothetical protein	-
GURA_RS07255	1663805..1664305	+	501	WP_011938343.1	DUF2059 domain-containing protein	-
GURA_RS07265	1664975..1666357	+	1383	WP_011938345.1	sigma-54 dependent transcriptional regulator	-
GURA_RS07270	1667133..1667384	+	252	WP_011938347.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-90)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-66)

Sequences

Toxin

Protein

• Length: 99 a.a.
• Molecular weight: 11172.77 Da
• Isoelectric Point: 7.0107

>T22095 WP_011938341.1 NC_009483:1662969-1663265 [Geobacter uraniireducens Rf4]
MRIVWSPLAVDRASEIAGYIAQDNPTAAENWVNAVFAQVGRLKSFPDRGRVVSEINNDSFRELIYGNYRIIYRIEEKQVS
ILTIRHGKQILPVDEILG

Nucleotide

• Length: 297 bp

>T22095 NC_009483:1662969-1663265 [Geobacter uraniireducens Rf4]
ATGAGGATAGTCTGGTCCCCTCTCGCAGTAGATAGGGCATCTGAAATAGCCGGATATATAGCCCAGGACAATCCAACCGC
AGCAGAAAATTGGGTAAATGCAGTCTTTGCACAAGTTGGGCGGTTAAAGTCGTTTCCCGATAGGGGGCGCGTTGTGTCGG
AAATCAATAACGATAGTTTTCGAGAACTGATTTACGGAAATTATAGAATTATTTACCGAATAGAAGAAAAACAGGTCTCT
ATTCTTACGATTCGGCATGGAAAGCAGATTTTACCTGTGGATGAAATTCTTGGATAA

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 8992.33 Da
• Isoelectric Point: 6.4632

>AT22095 WP_198134537.1 NC_009483:1662727-1662972 [Geobacter uraniireducens Rf4]
MSEFRTGIASFLKQVHDTKRPMIITQHGKGVAVLLDVNEYESMQEKIELLQDIQTSVSQLESGAGMENNDAKAMVLKRAG
K

Nucleotide

• Length: 246 bp

>AT22095 NC_009483:1662727-1662972 [Geobacter uraniireducens Rf4]
ATGTCCGAGTTCAGGACGGGGATCGCTTCGTTTCTTAAGCAGGTGCATGACACCAAACGACCTATGATTATTACCCAGCA
TGGTAAAGGCGTAGCCGTTTTACTTGATGTGAACGAATACGAATCCATGCAGGAAAAAATCGAACTTCTTCAGGATATAC
AAACGTCCGTCAGCCAGTTGGAAAGCGGCGCCGGCATGGAAAATAATGATGCAAAGGCAATGGTGCTGAAGCGAGCTGGA
AAATGA

Structures

Toxin

• AlphaFold DB: A5G9X3