Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2144669..2144937 Replicon chromosome
Accession NZ_CP085619
Organism Escherichia coli strain EC32

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2144797..2144899 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2144669..2144937 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LJN50_RS10390 2141222..2141884 - 663 WP_000944256.1 exodeoxyribonuclease X -
LJN50_RS10395 2141908..2142564 - 657 WP_000011664.1 carbon-nitrogen hydrolase family protein YobB -
LJN50_RS10400 2142666..2142896 - 231 WP_000916763.1 DNA polymerase III subunit theta -
LJN50_RS10405 2143035..2143409 + 375 WP_000168747.1 CopC domain-containing protein YobA -
LJN50_RS10410 2143413..2144285 + 873 WP_000879317.1 copper homeostasis membrane protein CopD -
LJN50_RS10415 2144298..2144639 + 342 WP_000976472.1 YebY family protein -
- 2144669..2144937 - 269 - - Antitoxin
- 2144797..2144899 + 103 - - Toxin
LJN50_RS10420 2145034..2145690 + 657 WP_000812745.1 protein-serine/threonine phosphatase -
LJN50_RS10425 2145691..2145882 - 192 WP_001296140.1 YebW family protein -
LJN50_RS10430 2145987..2146223 - 237 WP_001295499.1 YebV family protein -
LJN50_RS10435 2146340..2147779 - 1440 WP_001296139.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T220915 NZ_CP085619:2144797-2144899 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT220915 NZ_CP085619:c2144937-2144669 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATATTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References