Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/LOTUS_5_Limkain_b1-Phd |
| Location | 846758..847461 | Replicon | chromosome |
| Accession | NC_009483 | ||
| Organism | Geobacter uraniireducens Rf4 | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | A5GBX6 |
| Locus tag | GURA_RS03635 | Protein ID | WP_011937647.1 |
| Coordinates | 846758..847183 (-) | Length | 142 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | A5GBX7 |
| Locus tag | GURA_RS03640 | Protein ID | WP_011937648.1 |
| Coordinates | 847180..847461 (-) | Length | 94 a.a. |
Genomic Context
Location: 843368..843781 (414 bp)
Type: Others
Protein ID: WP_011937643.1
Type: Others
Protein ID: WP_011937643.1
Location: 843813..844487 (675 bp)
Type: Others
Protein ID: WP_011937644.1
Type: Others
Protein ID: WP_011937644.1
Location: 844575..845333 (759 bp)
Type: Others
Protein ID: WP_011937645.1
Type: Others
Protein ID: WP_011937645.1
Location: 845685..846662 (978 bp)
Type: Others
Protein ID: WP_011937646.1
Type: Others
Protein ID: WP_011937646.1
Location: 846758..847183 (426 bp)
Type: Toxin
Protein ID: WP_011937647.1
Type: Toxin
Protein ID: WP_011937647.1
Location: 847180..847461 (282 bp)
Type: Antitoxin
Protein ID: WP_011937648.1
Type: Antitoxin
Protein ID: WP_011937648.1
Location: 847700..848119 (420 bp)
Type: Others
Protein ID: WP_011937649.1
Type: Others
Protein ID: WP_011937649.1
Location: 848231..849565 (1335 bp)
Type: Others
Protein ID: WP_041245717.1
Type: Others
Protein ID: WP_041245717.1
Location: 849691..850176 (486 bp)
Type: Others
Protein ID: WP_011937651.1
Type: Others
Protein ID: WP_011937651.1
Location: 850223..850948 (726 bp)
Type: Others
Protein ID: WP_011937652.1
Type: Others
Protein ID: WP_011937652.1
Location: 851041..851874 (834 bp)
Type: Others
Protein ID: WP_011937653.1
Type: Others
Protein ID: WP_011937653.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| GURA_RS03615 | 843368..843781 | + | 414 | WP_011937643.1 | hypothetical protein | - |
| GURA_RS03620 | 843813..844487 | + | 675 | WP_011937644.1 | NAD(P)/FAD-dependent oxidoreductase | - |
| GURA_RS03625 | 844575..845333 | + | 759 | WP_011937645.1 | tRNA 2-thiocytidine(32) synthetase TtcA | - |
| GURA_RS03630 | 845685..846662 | + | 978 | WP_011937646.1 | 4Fe-4S binding protein | - |
| GURA_RS03635 | 846758..847183 | - | 426 | WP_011937647.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
| GURA_RS03640 | 847180..847461 | - | 282 | WP_011937648.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
| GURA_RS03645 | 847700..848119 | - | 420 | WP_011937649.1 | TraR/DksA family transcriptional regulator | - |
| GURA_RS03650 | 848231..849565 | - | 1335 | WP_041245717.1 | 30S ribosomal protein S12 methylthiotransferase RimO | - |
| GURA_RS03655 | 849691..850176 | - | 486 | WP_011937651.1 | YajQ family cyclic di-GMP-binding protein | - |
| GURA_RS03660 | 850223..850948 | - | 726 | WP_011937652.1 | outer membrane lipoprotein carrier protein LolA | - |
| GURA_RS03665 | 851041..851874 | - | 834 | WP_011937653.1 | outer membrane lipoprotein carrier protein LolA | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 142 a.a. Molecular weight: 15573.83 Da Isoelectric Point: 4.6940
>T22091 WP_011937647.1 NC_009483:c847183-846758 [Geobacter uraniireducens Rf4]
VKFLLDTCLISELVKKEPNAAVVNWLDEQDEQGLFLSVLTLGELQKGISKLSGSTRKDELQAWVEHDLAERFAGRILDLD
LETALAWGTLQGDAERKGEKLPVMDSLIAATATAHGLIVVTRNVKDIERCRAKVYSPWGDA
VKFLLDTCLISELVKKEPNAAVVNWLDEQDEQGLFLSVLTLGELQKGISKLSGSTRKDELQAWVEHDLAERFAGRILDLD
LETALAWGTLQGDAERKGEKLPVMDSLIAATATAHGLIVVTRNVKDIERCRAKVYSPWGDA
Download Length: 426 bp
>T22091 NC_009483:c847183-846758 [Geobacter uraniireducens Rf4]
GTGAAATTTCTTCTCGACACCTGCCTGATCTCCGAGCTGGTGAAAAAGGAACCGAATGCCGCTGTGGTAAACTGGCTGGA
CGAACAGGATGAGCAGGGTCTTTTCCTGAGTGTCCTGACCCTTGGAGAACTGCAAAAGGGAATCAGCAAGCTTTCCGGCA
GCACCAGGAAAGATGAGCTTCAGGCGTGGGTCGAGCATGATCTTGCGGAGCGTTTCGCCGGACGTATCCTTGATCTCGAC
CTGGAAACGGCTCTGGCCTGGGGAACGCTTCAGGGGGATGCTGAACGGAAGGGGGAAAAGCTGCCGGTAATGGATTCACT
CATAGCTGCCACGGCCACGGCACACGGATTGATCGTGGTAACGCGCAATGTCAAGGATATCGAGCGCTGCAGGGCCAAGG
TTTACAGTCCGTGGGGCGATGCATAA
GTGAAATTTCTTCTCGACACCTGCCTGATCTCCGAGCTGGTGAAAAAGGAACCGAATGCCGCTGTGGTAAACTGGCTGGA
CGAACAGGATGAGCAGGGTCTTTTCCTGAGTGTCCTGACCCTTGGAGAACTGCAAAAGGGAATCAGCAAGCTTTCCGGCA
GCACCAGGAAAGATGAGCTTCAGGCGTGGGTCGAGCATGATCTTGCGGAGCGTTTCGCCGGACGTATCCTTGATCTCGAC
CTGGAAACGGCTCTGGCCTGGGGAACGCTTCAGGGGGATGCTGAACGGAAGGGGGAAAAGCTGCCGGTAATGGATTCACT
CATAGCTGCCACGGCCACGGCACACGGATTGATCGTGGTAACGCGCAATGTCAAGGATATCGAGCGCTGCAGGGCCAAGG
TTTACAGTCCGTGGGGCGATGCATAA
Antitoxin
Download Length: 94 a.a. Molecular weight: 10760.15 Da Isoelectric Point: 8.7734
>AT22091 WP_011937648.1 NC_009483:c847461-847180 [Geobacter uraniireducens Rf4]
MKANKKDRLPHEREWQLQEAKNRLSQVVDSALHDGPQTITLRGKPAAVLVSFEEFKKLTQPRSTLSQFFRQSPLHDTELD
LSRSADFSREVEL
MKANKKDRLPHEREWQLQEAKNRLSQVVDSALHDGPQTITLRGKPAAVLVSFEEFKKLTQPRSTLSQFFRQSPLHDTELD
LSRSADFSREVEL
Download Length: 282 bp
>AT22091 NC_009483:c847461-847180 [Geobacter uraniireducens Rf4]
ATGAAAGCCAATAAAAAAGACCGATTGCCCCACGAACGTGAATGGCAGCTTCAGGAAGCCAAGAACCGATTGAGCCAGGT
AGTGGACTCGGCTCTTCATGATGGTCCGCAAACCATCACCTTGCGGGGCAAACCGGCGGCGGTCTTAGTCTCTTTTGAGG
AATTCAAAAAGCTGACTCAACCGCGGTCCACGTTATCGCAGTTCTTCAGACAATCACCGCTTCATGATACAGAGCTCGAT
CTCAGCCGCAGTGCCGATTTCTCCCGTGAGGTGGAACTGTGA
ATGAAAGCCAATAAAAAAGACCGATTGCCCCACGAACGTGAATGGCAGCTTCAGGAAGCCAAGAACCGATTGAGCCAGGT
AGTGGACTCGGCTCTTCATGATGGTCCGCAAACCATCACCTTGCGGGGCAAACCGGCGGCGGTCTTAGTCTCTTTTGAGG
AATTCAAAAAGCTGACTCAACCGCGGTCCACGTTATCGCAGTTCTTCAGACAATCACCGCTTCATGATACAGAGCTCGAT
CTCAGCCGCAGTGCCGATTTCTCCCGTGAGGTGGAACTGTGA