Detailed information of TA system TA022090

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /BrnT(toxin)
• Location: 698148..698622
• Replicon: chromosome
• Accession: NC_009483
• Organism: Geobacter uraniireducens Rf4

Toxin (Protein)

• Gene name: -
• Uniprot ID: A5GCB1
• Locus tag: GURA_RS02965
• Protein ID: WP_011937518.1
• Coordinates: 698362..698622 (-)
• Length: 87 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: A5GCB0
• Locus tag: GURA_RS02960
• Protein ID: WP_011937517.1
• Coordinates: 698148..698372 (-)
• Length: 75 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
GURA_RS02955	694745..698002	-	3258	WP_011937516.1	exodeoxyribonuclease V subunit beta	-
GURA_RS02960	698148..698372	-	225	WP_011937517.1	hypothetical protein	Antitoxin
GURA_RS02965	698362..698622	-	261	WP_011937518.1	BrnT family toxin	Toxin
GURA_RS02970	698679..701954	-	3276	WP_011937519.1	exodeoxyribonuclease V subunit gamma	-
GURA_RS02975	701989..703101	-	1113	WP_011937520.1	homoserine O-acetyltransferase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Ribonuclease toxin, BrnT, of type II toxin-antitoxin system (5-80)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 87 a.a.
• Molecular weight: 9999.29 Da
• Isoelectric Point: 5.1771

>T22090 WP_011937518.1 NC_009483:c698622-698362 [Geobacter uraniireducens Rf4]
MEFEFDTKKSGSNKTKHGIDFDEAQALWDDPDLLEIPVITSDEPRYLVIGKILGKHWSAVITYRSDKARIISVRRSRKEE
IDIYES

Nucleotide

• Length: 261 bp

>T22090 NC_009483:c698622-698362 [Geobacter uraniireducens Rf4]
ATGGAATTTGAATTCGACACCAAGAAAAGCGGCAGCAATAAAACAAAGCATGGGATTGACTTTGATGAAGCCCAAGCGCT
CTGGGATGACCCCGATTTGCTGGAAATCCCTGTAATAACGAGCGATGAACCAAGATACCTGGTAATCGGGAAGATTTTGG
GGAAGCATTGGTCAGCGGTTATTACGTACAGGAGCGACAAGGCAAGAATCATTTCCGTTCGCCGTTCTCGTAAAGAGGAG
ATTGATATCTATGAAAGCTAA

Antitoxin

Protein

• Length: 75 a.a.
• Molecular weight: 8731.06 Da
• Isoelectric Point: 10.2456

>AT22090 WP_011937517.1 NC_009483:c698372-698148 [Geobacter uraniireducens Rf4]
MKANEFDKLFDDGKDISKHLDVSKARRPEQEQKRVNVDFPLWMIHSLDKEARRLGVPRQSIIKVWVAERLEKAS

Nucleotide

• Length: 225 bp

>AT22090 NC_009483:c698372-698148 [Geobacter uraniireducens Rf4]
ATGAAAGCTAACGAATTTGACAAGTTATTTGACGACGGCAAGGATATTTCAAAGCACCTTGATGTGTCAAAGGCTAGAAG
GCCTGAGCAGGAGCAGAAAAGAGTAAATGTGGATTTCCCTTTGTGGATGATCCACTCCCTGGACAAGGAAGCAAGACGTT
TGGGCGTGCCCCGGCAATCCATCATCAAGGTCTGGGTAGCTGAGCGTCTGGAAAAGGCATCTTGA

Structures

Toxin

• AlphaFold DB: A5GCB1

Antitoxin

• AlphaFold DB: A5GCB0