Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-YefM
Location 373154..373659 Replicon chromosome
Accession NC_009483
Organism Geobacter uraniireducens Rf4

Toxin (Protein)


Gene name relE Uniprot ID A5GD15
Locus tag GURA_RS01600 Protein ID WP_011937255.1
Coordinates 373405..373659 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A5GD14
Locus tag GURA_RS01595 Protein ID WP_011937254.1
Coordinates 373154..373408 (+) Length 85 a.a.

Genomic Context

GURA_RS01595GURA_RS01600GURA_RS01580GURA_RS01585GURA_RS01590GURA_RS01605GURA_RS01610GURA_RS01615GURA_RS24035
Location: 373154..373408 (255 bp)
Type: Antitoxin
Protein ID: WP_011937254.1
Location: 373405..373659 (255 bp)
Type: Toxin
Protein ID: WP_011937255.1
Location: 371853..372263 (411 bp)
Type: Others
Protein ID: WP_041245655.1
Location: 372260..372499 (240 bp)
Type: Others
Protein ID: WP_011937252.1
Location: 372624..373025 (402 bp)
Type: Others
Protein ID: WP_011937253.1
Location: 373808..375217 (1410 bp)
Type: Others
Protein ID: WP_011937256.1
Location: 375468..376949 (1482 bp)
Type: Others
Protein ID: WP_011937257.1
Location: 377033..377626 (594 bp)
Type: Others
Protein ID: WP_011937258.1
Location: 377742..377975 (234 bp)
Type: Others
Protein ID: WP_157046103.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
GURA_RS01580371853..372263-411WP_041245655.1putative toxin-antitoxin system toxin component, PIN family-
GURA_RS01585372260..372499-240WP_011937252.1AbrB family transcriptional regulator-
GURA_RS01590372624..373025-402WP_011937253.1hypothetical protein-
GURA_RS01595373154..373408+255WP_011937254.1type II toxin-antitoxin system prevent-host-death family antitoxinAntitoxin
GURA_RS01600373405..373659+255WP_011937255.1Txe/YoeB family addiction module toxinToxin
GURA_RS01605373808..375217-1410WP_011937256.1NADH-quinone oxidoreductase subunit N-
GURA_RS01610375468..376949-1482WP_011937257.1NADH-quinone oxidoreductase subunit M-
GURA_RS01615377033..377626-594WP_011937258.1hypothetical protein-
GURA_RS24035377742..377975-234WP_157046103.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10081.57 Da        Isoelectric Point: 7.8531

>T22089 WP_011937255.1 NC_009483:373405-373659 [Geobacter uraniireducens Rf4]
MNVTFTPTALDDLRYWLKTDKRQAERILALLEEIRRTPFDGTGKPEPLRFQLAGCWSRRIDREHRLVYQVEESEIVVIAC
RYHY

Download         Length: 255 bp

>T22089 NC_009483:373405-373659 [Geobacter uraniireducens Rf4]
ATGAATGTTACGTTCACACCGACTGCTCTCGACGACCTGCGCTATTGGCTTAAGACCGATAAACGCCAGGCCGAACGGAT
CTTGGCGCTTCTTGAAGAAATTCGGCGAACCCCTTTTGATGGAACAGGAAAACCAGAACCCCTCCGTTTTCAGCTTGCCG
GTTGCTGGTCCCGCAGGATTGACAGGGAACATCGCCTTGTATACCAAGTGGAAGAAAGTGAGATTGTCGTTATCGCCTGT
CGCTATCACTACTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9435.72 Da        Isoelectric Point: 4.8254

>AT22089 WP_011937254.1 NC_009483:373154-373408 [Geobacter uraniireducens Rf4]
MHAITYSEARHALKDVMDEACSNHEPILITRRKGENVVLLSLEDYESIMESEYLLSSPANAARLMQSLEEARSGKRTPMD
TLGL

Download         Length: 255 bp

>AT22089 NC_009483:373154-373408 [Geobacter uraniireducens Rf4]
ATGCATGCAATCACATACAGCGAAGCACGTCATGCCCTTAAGGACGTCATGGACGAAGCTTGCAGCAACCACGAACCGAT
CCTGATCACGCGTCGTAAGGGAGAGAATGTAGTCCTGTTAAGCCTTGAAGACTACGAGTCCATTATGGAAAGCGAATATC
TGCTTTCCAGTCCTGCTAATGCAGCACGGCTAATGCAATCTCTTGAAGAGGCACGGTCCGGCAAGCGAACCCCCATGGAT
ACTCTTGGGCTATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA5GD15

Antitoxin

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Source
ID
Structure
AlphaFold DBA5GD14

References