Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1848021..1848166 Replicon chromosome
Accession NZ_CP085478
Organism Klebsiella pneumoniae strain Kp1604

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1848057..1848159 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1848021..1848166 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LI478_RS08920 1843151..1845211 + 2061 WP_004151449.1 oligopeptidase B -
LI478_RS08925 1845215..1845874 - 660 WP_002911407.1 exodeoxyribonuclease X -
LI478_RS08930 1845953..1846183 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LI478_RS08935 1846296..1846670 + 375 WP_004151448.1 CopC domain-containing protein YobA -
LI478_RS08940 1846674..1847543 + 870 WP_048331959.1 copper homeostasis membrane protein CopD -
LI478_RS08945 1847560..1847898 + 339 WP_016529031.1 YebY family protein -
- 1848021..1848166 - 146 - - Antitoxin
- 1848057..1848159 + 103 - - Toxin
LI478_RS08950 1848535..1848678 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
LI478_RS08955 1848783..1849751 - 969 WP_074185275.1 VirK/YbjX family protein -
LI478_RS08960 1849908..1850561 + 654 WP_032447686.1 protein-serine/threonine phosphatase -
LI478_RS08965 1850558..1850749 - 192 WP_002911395.1 YebW family protein -
LI478_RS08970 1850847..1851086 - 240 WP_002911393.1 YebV family protein -
LI478_RS08975 1851202..1852635 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T220766 NZ_CP085478:1848057-1848159 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT220766 NZ_CP085478:c1848166-1848021 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References