220740

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) spoIISABC/SpoIISA-SpoIISB
Location 2574977..2575895 Replicon chromosome
Accession NZ_CP085394
Organism Bacillus sp. CMF12

Toxin (Protein)


Gene name spoIISA Uniprot ID -
Locus tag LIT38_RS13075 Protein ID WP_243503161.1
Coordinates 2574977..2575741 (+) Length 255 a.a.

Antitoxin (Protein)


Gene name spoIISB Uniprot ID -
Locus tag LIT38_RS13080 Protein ID WP_243503162.1
Coordinates 2575722..2575895 (+) Length 58 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LIT38_RS13050 (LIT38_13055) 2570227..2570958 - 732 WP_243503157.1 3-deoxy-manno-octulosonate cytidylyltransferase -
LIT38_RS13055 (LIT38_13060) 2571161..2572723 - 1563 WP_243503158.1 TetR family transcriptional regulator C-terminal domain-containing protein -
LIT38_RS13060 (LIT38_13065) 2573006..2573179 - 174 WP_252218046.1 hypothetical protein -
LIT38_RS13065 (LIT38_13070) 2573199..2573651 + 453 WP_243503159.1 hypothetical protein -
LIT38_RS13070 (LIT38_13075) 2573758..2574552 - 795 WP_243503160.1 PHP domain-containing protein -
LIT38_RS13075 (LIT38_13080) 2574977..2575741 + 765 WP_243503161.1 type II toxin-antitoxin system SpoIISA family toxin Toxin
LIT38_RS13080 (LIT38_13085) 2575722..2575895 + 174 WP_243503162.1 type II toxin-antitoxin system SpoIISB family antitoxin Antitoxin
LIT38_RS13085 (LIT38_13090) 2576169..2577539 - 1371 WP_243503163.1 aldehyde dehydrogenase -
LIT38_RS13090 (LIT38_13095) 2577661..2578257 - 597 WP_252218047.1 flavin reductase family protein -
LIT38_RS13095 (LIT38_13100) 2578278..2579525 - 1248 WP_252218048.1 MFS transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SpoIISA, type II toxin-antitoxin system

(3-239)

Antitoxin

Antitoxin SpoIISB

(6-57)


Sequences

Toxin        


Download         Length: 255 a.a.        Molecular weight: 29971.66 Da        Isoelectric Point: 4.3116

>T220740 WP_243503161.1 NZ_CP085394:2574977-2575741 [Bacillus sp. CMF12]
MLLFFKIVVWMIVACLGFYVFSVWRWEKKVKERMFAIRKTWYIIYVLGAVIYWTKVPESIFTDWLNYLIVAIIFALVDAF
IFLGSYLKRVGNNELATDTMELLEENNDLLNSQMNKLKSFQYLLKNEPIDVYYGDMEAYIAGIEKLLADYAEKVDMKASL
CKYTTQEDKDYLLEHYPDKALIHSRLDRKEVYYDADEKLALIPFSILEDYYVIKLTSDDFVTEFDYLLFTSLISIYDLML
PAEQEDEDHEGTSG

Download         Length: 765 bp

>T220740 NZ_CP117267:566746-566991 [Rhizobium rhododendri]
ATGAAGGACGTTGTCGTATCCCGACTTGCCGACAAAGCACTTATGCGCATGCAGCCAAAACGGCGGCTGGCGATCATTGA
AAAAGTCAAAGCCTATGCGCGCGGAGAGATTGTCGACATCAAGAAGATGAAAGGCGGAAATCTCTACCGTATCAGGGTCG
GACTGGATCGGGTTATCATCGATGACAAGGGTAGGATTATCGTGGTCATCGATGCCGGTCCGCGGGGCAGTATCTACAAG
GATTGA

Antitoxin


Download         Length: 58 a.a.        Molecular weight: 6738.98 Da        Isoelectric Point: 10.8769

>AT220740 WP_243503162.1 NZ_CP085394:2575722-2575895 [Bacillus sp. CMF12]
MKEPADKEKHKLSTKNNMKIMKKKSRINLPDFEVSPHTERIIKENKRLISVYTKSKA

Download         Length: 174 bp

>AT220740 NZ_CP117267:566998-567360 [Rhizobium rhododendri]
ATGGGCGATATCAAGAGGTTCGAAATCGACGGCAAACCCTATGTGCTGTTGAGTGAAGAGGATTATGAGGATCTGGTCGA
TGGACTGAGGGCGAATGCTGTCCTGGCCGGGATTTCTGCAGGAGAAGAAACCTGGCCCTTGGAGATCGTTGAGGCGCGTG
CCAATGGCGGAAATGCCGTCCGTATCTTCCGAAACTATCGCCGCATGACTGTCACCGAACTTGCCATGGCCGCCGGAATT
TCGCAGCCCTATCTCTCTGAGATCGAGGCAGGCAAAAAAACCGGCAGTGTCGATGTCCTGAAGCGTATCGCTACCGCCCT
CAAGGTCGATCTCGACGATCTCGTCGTCGACGTGGCGGACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References