Detailed information of TA system TA022062

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): abiEi-abiEii/-
• Location: 946954..948386
• Replicon: chromosome
• Accession: NC_009442
• Organism: Streptococcus suis 05ZYH33

Toxin (Protein)

• Gene name: abiEi
• Uniprot ID: -
• Locus tag: SSU05_0967
• Protein ID: YP_001198333.1
• Coordinates: 947541..948386 (+)
• Length: 282 a.a.

Antitoxin (Protein)

• Gene name: abiEii
• Uniprot ID: -
• Locus tag: SSU05_0966
• Protein ID: YP_001198332.1
• Coordinates: 946954..947544 (+)
• Length: 197 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SSU05_0966	946954..947544	+	591	YP_001198332.1	transcriptional regulator	Antitoxin
SSU05_0967	947541..948386	+	846	YP_001198333.1	hypothetical protein	Toxin
SSU05_0968	948449..951250	-	2802	YP_001198334.1	Tn5252, Orf28	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (33-259)

Antitoxin

• Transcriptional regulator, AbiEi antitoxin (6-50)

Sequences

Toxin

Protein

• Length: 282 a.a.
• Molecular weight: 32518.29 Da
• Isoelectric Point: 5.2158

>T22062 YP_001198333.1 NC_009442:947541-948386 [Streptococcus suis 05ZYH33]
MNKAKLTALCHKISKNTGLTFNSVMTYYFLEVILKKLSQSTYSNHYIFKGGFLLSNVIGVESRSTVDIDFLFHQITLSED
TVKQQLKEILADSEEGISFVIQSITAIKESDDYGGYRATILCQLENIKQVIHLDIATGDVVTPQPITYDYKAIFDEENFP
IIAYTIETILAEKLQTIYSRNFLNSRSKDFYDVYILSKLKKEDIDFIQLKNACQRTFSYRETVLDFEKIIELLERFKSDP
IQNQQWQNYSKKYSYTKGISLADVLEEMIRLIAVLISINFD

Nucleotide

• Length: 846 bp

>T22062 NC_009442:947541-948386 [Streptococcus suis 05ZYH33]
ATGAATAAAGCTAAGCTAACAGCACTCTGTCATAAAATATCTAAGAATACTGGATTAACCTTTAATTCCGTGATGACCTA
TTACTTTCTAGAAGTGATTTTGAAAAAATTAAGTCAGAGTACCTACTCAAATCACTATATCTTCAAAGGAGGATTCCTAC
TGTCAAATGTTATTGGAGTTGAATCTCGTAGCACGGTTGATATTGATTTTTTGTTCCATCAAATAACACTCTCAGAAGAT
ACTGTGAAGCAGCAACTCAAAGAAATTTTAGCAGATTCAGAAGAAGGTATATCTTTTGTGATTCAATCCATCACAGCTAT
TAAAGAAAGTGATGACTATGGTGGCTATCGAGCAACAATTTTGTGCCAACTTGAGAATATTAAACAAGTTATCCATTTGG
ATATTGCGACAGGCGATGTTGTAACTCCTCAGCCGATTACATACGACTATAAAGCTATTTTTGATGAAGAAAATTTTCCA
ATCATTGCTTATACAATTGAAACAATCCTAGCTGAGAAACTTCAAACCATCTATTCACGTAACTTCTTGAACAGCAGAAG
CAAAGATTTTTACGATGTTTATATTCTTTCAAAACTGAAGAAAGAAGACATTGACTTCATTCAATTGAAAAATGCCTGTC
AGAGAACATTTTCATATCGCGAAACAGTGCTCGATTTTGAAAAGATTATTGAACTACTCGAGAGGTTCAAATCTGACCCT
ATTCAGAATCAACAATGGCAAAATTATTCGAAAAAATATAGCTATACAAAGGGAATTTCCCTTGCAGATGTTCTTGAGGA
GATGATTCGTCTCATAGCAGTTCTCATTTCTATAAATTTTGATTAA

Antitoxin

Protein

• Length: 197 a.a.
• Molecular weight: 23151.74 Da
• Isoelectric Point: 7.8272

>AT22062 YP_001198332.1 NC_009442:946954-947544 [Streptococcus suis 05ZYH33]
MSKKEILLEFIENHNGIITYKDCKALNIPTIYLTRLEKEGILYRVEKGIFLTQNGDYDEYYFFQYRYPKAVFSYISALYL
QQFTDEIPQYFDVTIPRGYRFNTPPANLNIHSVSKENSELGITLVKTPMGNEVRVYDFERIICDFVIHREKIDTELFVKT
LQLYGNYPKKNLTKLYEYATKMSTLAKVKQTLEVLV

Nucleotide

• Length: 591 bp

>AT22062 NC_009442:946954-947544 [Streptococcus suis 05ZYH33]
ATGTCAAAAAAAGAGATTCTACTTGAATTTATAGAAAACCACAATGGCATTATCACCTATAAAGATTGTAAAGCTCTAAA
TATTCCAACAATATATTTGACAAGACTAGAAAAAGAAGGAATTCTATACCGCGTCGAAAAAGGAATTTTCCTAACCCAGA
ATGGAGACTACGACGAATACTACTTCTTTCAGTACCGATATCCGAAAGCTGTTTTCTCATATATCTCAGCGCTTTATCTG
CAACAATTTACAGATGAAATTCCTCAATATTTTGACGTAACCATTCCTAGAGGTTACCGTTTTAATACTCCTCCAGCTAA
TCTGAACATTCATTCCGTTTCTAAGGAAAATAGCGAACTAGGAATTACTCTTGTAAAAACCCCTATGGGAAACGAGGTAA
GAGTGTATGATTTCGAACGTATTATCTGTGATTTTGTGATTCATCGAGAAAAAATAGATACTGAGCTTTTTGTCAAAACA
CTTCAACTTTACGGAAACTATCCTAAAAAAAATCTTACAAAACTCTATGAATATGCGACAAAAATGAGCACCTTGGCCAA
GGTCAAACAAACTCTGGAGGTCCTAGTATGA