Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2014504..2014738 | Replicon | chromosome |
| Accession | NZ_CP085202 | ||
| Organism | Shigella flexneri strain P099 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2014634..2014737 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2014504..2014738 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| IUX27_RS09895 | 2011059..2011721 | - | 663 | WP_000944268.1 | exodeoxyribonuclease X | - |
| IUX27_RS09900 | 2011745..2012401 | - | 657 | Protein_1909 | carbon-nitrogen hydrolase family protein YobB | - |
| IUX27_RS09905 | 2012503..2012733 | - | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| IUX27_RS09910 | 2012872..2013246 | + | 375 | WP_000168747.1 | CopC domain-containing protein YobA | - |
| IUX27_RS09915 | 2013250..2014122 | + | 873 | Protein_1912 | copper homeostasis membrane protein CopD | - |
| IUX27_RS09920 | 2014135..2014476 | + | 342 | WP_000976476.1 | YebY family protein | - |
| - | 2014504..2014738 | - | 235 | - | - | Antitoxin |
| - | 2014634..2014737 | + | 104 | - | - | Toxin |
| IUX27_RS09925 | 2014869..2015946 | - | 1078 | Protein_1914 | phage integrase Arm DNA-binding domain-containing protein | - |
| IUX27_RS09930 | 2015912..2016193 | - | 282 | WP_005127484.1 | excisionase | - |
| IUX27_RS09935 | 2016310..2017158 | - | 849 | Protein_1916 | IS3-like element IS600 family transposase | - |
| IUX27_RS09940 | 2017213..2018408 | + | 1196 | Protein_1917 | IS3 family transposase | - |
| IUX27_RS09945 | 2018451..2018761 | - | 311 | Protein_1918 | transposase | - |
| IUX27_RS09950 | 2018825..2019292 | + | 468 | Protein_1919 | DNA-binding transcriptional regulator PgrR | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T220616 NZ_CP085202:2014634-2014737 [Shigella flexneri]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT220616 NZ_CP085202:c2014738-2014504 [Shigella flexneri]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
