Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2558122..2558269 Replicon chromosome
Accession NZ_CP085197
Organism Klebsiella quasipneumoniae strain NDM-101

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2558163..2558265 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2558122..2558269 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LH783_RS12295 2553257..2555317 + 2061 WP_065904503.1 oligopeptidase B -
LH783_RS12300 2555321..2555980 - 660 WP_065904507.1 exodeoxyribonuclease X -
LH783_RS12305 2556059..2556289 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LH783_RS12310 2556402..2556776 + 375 WP_004203386.1 CopC domain-containing protein YobA -
LH783_RS12315 2556780..2557649 + 870 WP_004203385.1 copper homeostasis membrane protein CopD -
LH783_RS12320 2557666..2558004 + 339 WP_002911404.1 YebY family protein -
- 2558122..2558269 - 148 - - Antitoxin
- 2558163..2558265 + 103 - - Toxin
LH783_RS12325 2558653..2558796 - 144 WP_032425946.1 Ecr family regulatory small membrane protein -
LH783_RS12330 2558900..2559868 - 969 WP_065904512.1 VirK/YbjX family protein -
LH783_RS12335 2560025..2560678 + 654 WP_004203382.1 protein-serine/threonine phosphatase -
LH783_RS12340 2560675..2560866 - 192 WP_002911395.1 YebW family protein -
LH783_RS12345 2560964..2561203 - 240 WP_002911393.1 YebV family protein -
LH783_RS12350 2561320..2562753 - 1434 WP_017900211.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T220598 NZ_CP085197:2558163-2558265 [Klebsiella quasipneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 148 bp

>AT220598 NZ_CP085197:c2558269-2558122 [Klebsiella quasipneumoniae]
AGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTG
GCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGTCTGCG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References