22058

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/-
Location 596757..597114 Replicon chromosome
Accession NC_009442
Organism Streptococcus suis 05ZYH33

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag SSU05_0616 Protein ID YP_001197982.1
Coordinates 596980..597114 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag SSU05_0615 Protein ID YP_001197981.1
Coordinates 596757..596942 (+) Length 62 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SSU05_0608 591828..592277 - 450 YP_001197974.1 transcriptional regulator -
SSU05_0609 592748..592921 + 174 YP_001197975.1 transposase -
SSU05_0610 592939..593196 + 258 YP_001197976.1 transposase -
SSU05_0611 593213..593419 + 207 YP_001197977.1 transposase -
SSU05_0612 593478..593975 + 498 YP_001197978.1 hypothetical protein -
SSU05_0613 593972..595153 + 1182 YP_001197979.1 aspartate aminotransferase -
SSU05_0614 595168..596694 + 1527 YP_001197980.1 asparaginyl-tRNA synthetase -
SSU05_0615 596757..596942 + 186 YP_001197981.1 hypothetical protein Antitoxin
SSU05_0616 596980..597114 + 135 YP_001197982.1 hypothetical protein Toxin
SSU05_0617 597324..597467 + 144 YP_001197983.1 hypothetical protein -
SSU05_0618 597646..598977 + 1332 YP_001197984.1 Na+-driven multidrug efflux pump -
SSU05_0619 599028..599405 + 378 YP_001197985.1 YjgF family translation initiation inhibitor -
SSU05_0620 599427..600314 + 888 YP_001197986.1 hypothetical protein -
SSU05_0621 600311..601285 + 975 YP_001197987.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Protein of unknown function DUF6290

(14-57)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 5366.49 Da        Isoelectric Point: 10.4691

>T22058 YP_001197982.1 NC_009442:596980-597114 [Streptococcus suis 05ZYH33]
MMSWRIKKMVYNLVLSDNAWNHLKKWDRLVGIMLARDWEMLAMA

Download         Length: 135 bp

>T22058 NC_009442:596980-597114 [Streptococcus suis 05ZYH33]
ATGATGTCCTGGCGGATTAAAAAAATGGTTTATAACCTTGTTCTCAGCGATAATGCTTGGAACCATTTGAAAAAATGGGA
CAGGCTTGTGGGGATAATGCTTGCTAGGGATTGGGAAATGCTTGCTATGGCTTAA

Antitoxin


Download         Length: 62 a.a.        Molecular weight: 7046.32 Da        Isoelectric Point: 11.0486

>AT22058 YP_001197981.1 NC_009442:596757-596942 [Streptococcus suis 05ZYH33]
MFNKKKVGGMRGLVSWQLTDAKKKFFKTFAFHTGKTLSDLSKTALAEQIKNHWDYKLGIRV

Download         Length: 186 bp

>AT22058 NC_009442:596757-596942 [Streptococcus suis 05ZYH33]
TTGTTTAACAAAAAAAAAGTGGGTGGAATGAGGGGATTGGTTTCCTGGCAATTAACCGATGCAAAAAAAAAATTTTTCAA
AACCTTTGCTTTTCATACGGGAAAAACCCTGTCTGACCTATCCAAAACTGCACTTGCTGAACAAATAAAAAACCATTGGG
ACTATAAATTGGGTATCAGGGTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References