Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2099080..2099351 Replicon chromosome
Accession NZ_CP085188
Organism Escherichia coli strain EC195

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2099210..2099313 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2099080..2099351 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LIN52_RS10135 2095635..2096297 - 663 WP_000944256.1 exodeoxyribonuclease X -
LIN52_RS10140 2096321..2096977 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
LIN52_RS10145 2097079..2097309 - 231 WP_000916763.1 DNA polymerase III subunit theta -
LIN52_RS10150 2097448..2097822 + 375 WP_000204699.1 CopC domain-containing protein YobA -
LIN52_RS10155 2097826..2098698 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
LIN52_RS10160 2098711..2099052 + 342 WP_000976492.1 YebY family protein -
- 2099080..2099351 - 272 - - Antitoxin
- 2099210..2099313 + 104 - - Toxin
LIN52_RS10165 2099448..2100104 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
LIN52_RS10170 2100105..2100296 - 192 WP_001296140.1 YebW family protein -
LIN52_RS10175 2100401..2100637 - 237 WP_001295499.1 YebV family protein -
LIN52_RS10180 2100755..2102194 - 1440 WP_000057023.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T220574 NZ_CP085188:2099210-2099313 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT220574 NZ_CP085188:c2099351-2099080 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References