Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | /Acetyltransf_4(toxin) |
Location | 3672071..3673482 | Replicon | chromosome |
Accession | NC_009439 | ||
Organism | Pseudomonas mendocina ymp |
Toxin (Protein)
Gene name | - | Uniprot ID | - |
Locus tag | PMEN_RS16765 | Protein ID | WP_012019410.1 |
Coordinates | 3672913..3673482 (-) | Length | 190 a.a. |
Antitoxin (Protein)
Gene name | - | Uniprot ID | - |
Locus tag | PMEN_RS16760 | Protein ID | WP_012019409.1 |
Coordinates | 3672071..3672910 (-) | Length | 280 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
PMEN_RS16745 (Pmen_3324) | 3668988..3669893 | - | 906 | WP_012019406.1 | hypothetical protein | - |
PMEN_RS16750 (Pmen_3325) | 3669895..3670467 | - | 573 | WP_012019407.1 | LemA family protein | - |
PMEN_RS16755 (Pmen_3326) | 3670658..3671995 | + | 1338 | WP_012019408.1 | peptidase | - |
PMEN_RS16760 (Pmen_3327) | 3672071..3672910 | - | 840 | WP_012019409.1 | AraC family transcriptional regulator | Antitoxin |
PMEN_RS16765 (Pmen_3328) | 3672913..3673482 | - | 570 | WP_012019410.1 | GNAT family N-acetyltransferase | Toxin |
PMEN_RS16770 (Pmen_3329) | 3673683..3677170 | + | 3488 | Protein_3346 | PAS-domain containing protein | - |
PMEN_RS16775 (Pmen_3330) | 3677212..3678066 | - | 855 | WP_085986191.1 | MerR family transcriptional regulator | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 190 a.a. Molecular weight: 21347.51 Da Isoelectric Point: 9.5184
>T22056 WP_012019410.1 NC_009439:c3673482-3672913 [Pseudomonas mendocina ymp]
MFKPQLVTLQRGALRLEPLADADIPALVALAEANRDELLYMSGTQRLDWYRSALAELREQRALPFAIRLGEQLVGTTRFG
DFMNSLPACEIGWTWLDRAQHGSGLNASIKYLMLKHAFDNWGMVRVQLKTAASNLRSQRAIEKLGAAREGLLRNHRRLAD
GRLDDTVLYSITDQEWPQVRAVLEARFGG
MFKPQLVTLQRGALRLEPLADADIPALVALAEANRDELLYMSGTQRLDWYRSALAELREQRALPFAIRLGEQLVGTTRFG
DFMNSLPACEIGWTWLDRAQHGSGLNASIKYLMLKHAFDNWGMVRVQLKTAASNLRSQRAIEKLGAAREGLLRNHRRLAD
GRLDDTVLYSITDQEWPQVRAVLEARFGG
Download Length: 570 bp
>T22056 NC_009439:c3673482-3672913 [Pseudomonas mendocina ymp]
ATGTTCAAACCGCAATTGGTCACGCTGCAGCGAGGAGCCTTGCGCCTGGAGCCACTGGCCGATGCCGATATCCCGGCCCT
GGTCGCGCTGGCCGAGGCCAATCGTGACGAGCTGCTGTACATGAGCGGTACCCAGCGTCTGGACTGGTATCGCAGCGCAC
TGGCCGAACTGCGCGAGCAACGCGCGCTGCCATTCGCCATCCGTCTCGGCGAGCAGCTGGTCGGCACCACTCGCTTCGGC
GATTTCATGAACAGCCTGCCGGCCTGCGAGATCGGCTGGACCTGGCTCGATCGCGCCCAGCATGGCAGCGGGCTGAACGC
CAGCATCAAGTACCTGATGCTCAAGCATGCCTTCGACAACTGGGGCATGGTCCGTGTGCAGCTGAAAACCGCCGCCAGCA
ACCTGCGCTCGCAACGCGCCATCGAGAAGCTGGGCGCCGCCCGCGAGGGCCTGCTGCGTAACCATCGCCGCCTGGCCGAC
GGCCGTCTCGACGACACGGTGCTGTACAGCATCACCGATCAGGAATGGCCGCAGGTGCGCGCCGTCCTGGAAGCGCGCTT
CGGCGGCTGA
ATGTTCAAACCGCAATTGGTCACGCTGCAGCGAGGAGCCTTGCGCCTGGAGCCACTGGCCGATGCCGATATCCCGGCCCT
GGTCGCGCTGGCCGAGGCCAATCGTGACGAGCTGCTGTACATGAGCGGTACCCAGCGTCTGGACTGGTATCGCAGCGCAC
TGGCCGAACTGCGCGAGCAACGCGCGCTGCCATTCGCCATCCGTCTCGGCGAGCAGCTGGTCGGCACCACTCGCTTCGGC
GATTTCATGAACAGCCTGCCGGCCTGCGAGATCGGCTGGACCTGGCTCGATCGCGCCCAGCATGGCAGCGGGCTGAACGC
CAGCATCAAGTACCTGATGCTCAAGCATGCCTTCGACAACTGGGGCATGGTCCGTGTGCAGCTGAAAACCGCCGCCAGCA
ACCTGCGCTCGCAACGCGCCATCGAGAAGCTGGGCGCCGCCCGCGAGGGCCTGCTGCGTAACCATCGCCGCCTGGCCGAC
GGCCGTCTCGACGACACGGTGCTGTACAGCATCACCGATCAGGAATGGCCGCAGGTGCGCGCCGTCCTGGAAGCGCGCTT
CGGCGGCTGA
Antitoxin
Download Length: 280 a.a. Molecular weight: 30970.13 Da Isoelectric Point: 7.7422
>AT22056 WP_012019409.1 NC_009439:c3672910-3672071 [Pseudomonas mendocina ymp]
MQPLTGSERARFSASDDLHGLELLSARFVEHRFAPHVHDGHVIAVLEAGAERYRYRGVDHLAGAGSIALLNPDEVHTGSK
GVEQGWQYRVFYPQPGTFEALLAELESPPAAPPMFHDSVHHDPLLASRLSALHRLLEDPHSEALQRQTLWREAMLELLQR
YARLPAPRGIGQEPRAVALAKELLASQLSEPPSLEELAAAVNLSPFHFARVFRRATGLPPHAWLRQRRLEQARTLLRSGC
SALSVAMQLGFADQSHLSRQFKQTYGVSPGEYRSAVARG
MQPLTGSERARFSASDDLHGLELLSARFVEHRFAPHVHDGHVIAVLEAGAERYRYRGVDHLAGAGSIALLNPDEVHTGSK
GVEQGWQYRVFYPQPGTFEALLAELESPPAAPPMFHDSVHHDPLLASRLSALHRLLEDPHSEALQRQTLWREAMLELLQR
YARLPAPRGIGQEPRAVALAKELLASQLSEPPSLEELAAAVNLSPFHFARVFRRATGLPPHAWLRQRRLEQARTLLRSGC
SALSVAMQLGFADQSHLSRQFKQTYGVSPGEYRSAVARG
Download Length: 840 bp
>AT22056 NC_009439:c3672910-3672071 [Pseudomonas mendocina ymp]
ATGCAGCCACTGACGGGAAGCGAACGCGCGCGGTTCAGCGCCAGCGACGATCTGCACGGGTTGGAGCTGTTGTCCGCACG
CTTTGTCGAACACCGTTTCGCCCCGCACGTGCACGACGGTCATGTGATCGCCGTGCTCGAAGCCGGTGCTGAGCGCTATC
GCTATCGCGGTGTCGATCACCTGGCGGGCGCCGGCAGCATCGCCTTGCTCAATCCGGACGAGGTGCATACCGGTTCCAAA
GGGGTCGAGCAAGGCTGGCAGTACCGGGTGTTCTACCCGCAGCCCGGTACATTCGAGGCGCTGCTGGCCGAACTCGAGTC
GCCACCGGCTGCACCGCCGATGTTCCACGACAGCGTGCACCATGATCCGCTCCTAGCGTCGCGGCTGAGTGCGCTGCACC
GTCTGCTGGAGGATCCGCACAGCGAGGCGCTGCAACGTCAGACCCTGTGGCGCGAGGCGATGCTCGAGCTGCTGCAGCGT
TACGCGCGCCTGCCGGCGCCGCGTGGCATCGGCCAGGAACCGCGGGCGGTGGCGTTGGCCAAGGAGCTGCTTGCCAGTCA
GCTGAGCGAGCCGCCATCGCTGGAAGAGCTGGCGGCAGCGGTCAATCTCTCACCCTTTCACTTCGCCCGGGTGTTCCGCC
GGGCCACCGGTCTGCCACCGCATGCCTGGCTCAGGCAGCGCCGTCTGGAGCAGGCGCGGACGCTGCTTAGAAGCGGCTGT
TCGGCGCTTAGCGTCGCCATGCAGCTGGGGTTCGCCGACCAGAGCCATTTGTCGCGGCAGTTCAAGCAAACCTATGGCGT
CAGTCCCGGCGAATACCGCAGCGCGGTGGCGCGAGGCTGA
ATGCAGCCACTGACGGGAAGCGAACGCGCGCGGTTCAGCGCCAGCGACGATCTGCACGGGTTGGAGCTGTTGTCCGCACG
CTTTGTCGAACACCGTTTCGCCCCGCACGTGCACGACGGTCATGTGATCGCCGTGCTCGAAGCCGGTGCTGAGCGCTATC
GCTATCGCGGTGTCGATCACCTGGCGGGCGCCGGCAGCATCGCCTTGCTCAATCCGGACGAGGTGCATACCGGTTCCAAA
GGGGTCGAGCAAGGCTGGCAGTACCGGGTGTTCTACCCGCAGCCCGGTACATTCGAGGCGCTGCTGGCCGAACTCGAGTC
GCCACCGGCTGCACCGCCGATGTTCCACGACAGCGTGCACCATGATCCGCTCCTAGCGTCGCGGCTGAGTGCGCTGCACC
GTCTGCTGGAGGATCCGCACAGCGAGGCGCTGCAACGTCAGACCCTGTGGCGCGAGGCGATGCTCGAGCTGCTGCAGCGT
TACGCGCGCCTGCCGGCGCCGCGTGGCATCGGCCAGGAACCGCGGGCGGTGGCGTTGGCCAAGGAGCTGCTTGCCAGTCA
GCTGAGCGAGCCGCCATCGCTGGAAGAGCTGGCGGCAGCGGTCAATCTCTCACCCTTTCACTTCGCCCGGGTGTTCCGCC
GGGCCACCGGTCTGCCACCGCATGCCTGGCTCAGGCAGCGCCGTCTGGAGCAGGCGCGGACGCTGCTTAGAAGCGGCTGT
TCGGCGCTTAGCGTCGCCATGCAGCTGGGGTTCGCCGACCAGAGCCATTTGTCGCGGCAGTTCAAGCAAACCTATGGCGT
CAGTCCCGGCGAATACCGCAGCGCGGTGGCGCGAGGCTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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